CAS 1190378-57-4

N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide

Description:

N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide, identified by its CAS number 1190378-57-4, is a synthetic organic compound characterized by its complex molecular structure, which includes multiple functional groups such as amines and carboxamides. This compound features a cyclobutane ring and a cyclopropyl group, contributing to its unique three-dimensional conformation. The presence of a pyrimidine ring and a morpholine moiety suggests potential biological activity, possibly as a pharmaceutical agent. Its molecular interactions may involve hydrogen bonding and hydrophobic interactions due to the diverse functional groups. The compound's solubility, stability, and reactivity can vary based on environmental conditions such as pH and temperature. As a result, it may exhibit specific pharmacokinetic properties, influencing its absorption, distribution, metabolism, and excretion in biological systems. Further studies would be necessary to elucidate its precise biological mechanisms and potential therapeutic applications.

Formula: C₂₆H₃₆N₆O₂

Synonyms:

• MRT68921
• CS-2840
• Cyclobutanecarboxamide, N-[3-[[5-cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]-
• IKKε/TBK1 Inhibitor II, MRT67307 - CAS 1190378-57-4 - Calbiochem
• MRT67307 HCl
• MRT67307 (free base)
• N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]-cyclobutanecarboxamide hydrochloride
• N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide
• MRT67307
• MRT67307 hydrochloride

N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide

CAS: 1190378-57-4

Formula: C₂₆H₃₆N₆O₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 464.6030

Ref: IN-DA008TID

MRT67307

CAS: 1190378-57-4

MRT67307

Purity: ≥98%

Molecular weight: 464.6g/mol

Ref: 54-BUP03337

MRT67307 hydrochloride

CAS: 1190378-57-4

MRT67307 hydrochloride

Purity: 99%

Molecular weight: 464.6g/mol

Ref: 54-OR1024035

MRT67307

CAS: 1190378-57-4

Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy.

Formula: C₂₆H₃₆N₆O₂

Purity: 99.25% - 99.84%

Color and Shape: Solid

Molecular weight: 464.6

Ref: TM-T0097

MRT67307

CAS: 1190378-57-4

Purity: 99%

Molecular weight: 464.29

Ref: 10-F863236

IKKµ/TBK1 Inhibitor II, MRT67307

CAS: 1190378-57-4

MRT67307 is an IKKµ/TBK1 inhibitor that has been shown to be clinically relevant in animal models of inflammatory bowel disease. MRT67307 inhibits the activation of IKKµ and TBK1, which are upstream kinases in the inflammatory pathway. MRT67307 blocks the production of pro-inflammatory cytokines and chemokines, leading to suppression of inflammation. In addition, MRT67307 has been shown to increase autophagy and inhibit Toll-like receptor 4 signaling in vitro, suggesting a potential therapeutic role for this drug in other diseases such as infectious diseases.

Formula: C₂₆H₃₆N₆O₂

Purity: Min. 95%

Molecular weight: 464.6 g/mol

Ref: 3D-QXB37857