CAS 1229-29-4: Doxepin hydrochloride

Description: Doxepin hydrochloride is a tricyclic antidepressant primarily used to treat depression and anxiety disorders, as well as insomnia. It functions by inhibiting the reuptake of neurotransmitters such as norepinephrine and serotonin, thereby enhancing mood and promoting sleep. This compound appears as a white to off-white crystalline powder and is soluble in water, making it suitable for various pharmaceutical formulations. Doxepin hydrochloride exhibits a relatively long half-life, allowing for once-daily dosing in many cases. Its pharmacological effects can include sedation, which is beneficial for patients with sleep disturbances. However, it may also lead to side effects such as dry mouth, dizziness, and weight gain. Due to its anticholinergic properties, caution is advised in patients with certain pre-existing conditions, such as glaucoma or urinary retention. Overall, doxepin hydrochloride is a versatile medication with a well-established profile in the management of mood and sleep disorders.

Formula: C₁₉H₂₁NO·ClH

InChI: InChI=1S/C19H21NO.ClH/c1-20(2)13-7-11-17-16-9-4-3-8-15(16)14-21-19-12-6-5-10-18(17)19;/h3-6,8-12H,7,13-14H2,1-2H3;1H

InChI key: InChIKey=MHNSPTUQQIYJOT-UHFFFAOYSA-N

SMILES: Cl.O1C=2C=CC=CC2C(=CCCN(C)C)C=3C=CC=CC3C1

Synonyms:

• (3E)-3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine hydrochloride
• (3Z)-3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine hydrochloride
• 1-Propanamine, 3-(dibenz[b,e]oxepin-11(6H)-ylidene)-N,N-dimethyl-, hydrochloride (1:1)
• 1-Propanamine, 3-dibenz[b,e]oxepin-11(6H)-ylidene-N,N-dimethyl-, hydrochloride
• 11-(3-Dimethylaminopropylidene)-6,11-Dihydro-Benz[B,E]Oxepin Hcl
• 3-(6,11-Dihydrodibenz(B,E)Oxepin-11-Ylidene)Propyldimethylamine Hcl
• 3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine hydrochloride (1:1)
• Adapin
• Aponal
• Curatin
• Dibenz[b,e]oxepin, 1-propanamine deriv.
• Dibenz[b,e]oxepin-Δ¹¹⁽⁶^H^),γ-propylamine, N,N-dimethyl-, hydrochloride
• Doxepin Hydrochloride
• Doxepine hydrochloride
• N,N-Dimethyldibenz[b,e]oxepin-Δ¹¹⁽⁶^H^),γ-propylamine hydrochloride
• P 3693A
• Quitaxon
• Silenor
• Sinequan
• Sinequin
• DOXEPINONE HCl
• Dibenz[b,e]oxepin-Δ11(6H),γ-propylamine, N,N-dimethyl-, hydrochloride

Doxepin hydrochloride

CAS: 1229-29-4

It is a highly potent H1 histamine receptor antagonist (Kd = 310 pM) and tricyclic …

• Formula: C₁₉H₂₂ClNO
• Molecular weight: 315.84

Doxepin hydrochloride

CAS: 1229-29-4

• Formula: C₁₉H₂₁NOHCl
• Purity: 99.5% / 21.7%
• Color and Shape: White

Doxepin hydrochloride CRS

CAS: 1229-29-4

• Formula: C₁₉H₂₂ClNO
• Color and Shape: Crystalline Powder. White. Whitish. Powder.
• Molecular weight: 315.8371

Doxepin for system suitability CRS

CAS: 1229-29-4

• Formula: C₁₉H₂₂ClNO
• Color and Shape: Crystalline Powder. White. Whitish. Powder.
• Molecular weight: 315.8371

Doxepin impurity standard

CAS: 1225-56-5 1229-29-44504-87-4 4504-88-5

• Color and Shape: White

Doxepin Hydrochloride

CAS: 1229-29-4

Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoi

• Formula: C₁₉H₂₁NO·ClH
• Color and Shape: White Powder
• Molecular weight: 315.13899

Doxepin hydrochloride

CAS: 1229-29-4

Doxepin hydrochloride, a dibenzoxepin tricyclic, blocks monoamine reuptake and has anticholinergic and antihistaminic effects. Mechanism …

• Formula: C₁₉H₂₂ClNO
• Purity: 99.57% - 99.91%
• Color and Shape: White To Off-White Powder
• Molecular weight: 315.837

1-Propanamine, 3-(dibenz[b,e]oxepin-11(6H)-ylidene)-N,N-dimethyl-, hydrochloride (1:1)

CAS: 1229-29-4

• Formula: C₁₉H₂₂ClNO
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 315.8371

Doxepin HCl (Mixture of Z and E Isomer)

CAS: 1229-29-4

• Formula: C₁₉H₂₁NO·HCl
• Color and Shape: White To Off-White Solid
• Molecular weight: 279.39 36.46

Doxepin hydrochloride

CAS: 1229-29-4

• Purity: 99.9%
• Molecular weight: 315.837g/mol

Doxepin Hydrochloride

CAS: 1229-29-4

• Molecular weight: 315.84g/mol

Doxepin hydrochloride

CAS: 1229-29-4

• Formula: C₁₉H₂₁NOHCl
• Molecular weight: 315.84

Doxepin Hydrochloride (mixture of isomers)

CAS: 1229-29-41668-19-5

• Formula: C₁₉H₂₁NO·HCl
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 315.84

Doxepin hydrochloride

CAS: 1229-29-4

• Formula: C₁₉H₂₁NO·ClH
• Color and Shape: Neat
• Molecular weight: 315.84

Doxepin Hydrochloride

CAS: 1229-29-4

• Formula: C₁₉H₂₁NO·ClH
• Color and Shape: Neat
• Molecular weight: 315.84

Doxepin Hydrochloride

CAS: 1229-29-4

Stability Hygroscopic Applications Doxepin is used clinically to treat anxiety and depression. Doxepin is an …

• Formula: C₁₉H₂₁NO·ClH
• Color and Shape: Neat
• Molecular weight: 315.84

Doxepin-13C, d3 .xHydrochloride

CAS: 1229-29-4

• Formula: C₁₈CH₁₈D₃NO•x(HCl)
• Color and Shape: Neat
• Molecular weight: 318.15782

Doxepin hydrochloride

CAS: 1229-29-4

Histamine receptor H1 antagonist; tricyclic antidepressant

• Formula: C₁₉H₂₂ClNO
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 315.84 g/mol

Doxepin HCl - Bio-X ™

CAS: 1229-29-4

Doxepin is a psychotropic agent that is used in the treatment of depression, anxiety and …

• Formula: C₁₉H₂₁NO•HCl
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 315.84 g/mol