CAS 131189-57-6

Cornuside

Description:

Cornuside, with the CAS number 131189-57-6, is a natural compound primarily derived from the Cornus species, particularly the dogwood tree. It is classified as a flavonoid glycoside, which means it consists of a flavonoid moiety linked to a sugar molecule. Cornuside is known for its potential pharmacological properties, including anti-inflammatory, antioxidant, and neuroprotective effects. Its structure typically features a flavonoid backbone, which contributes to its biological activity and interaction with various cellular pathways. Research has indicated that cornuside may play a role in modulating oxidative stress and inflammation, making it of interest in the context of various health conditions. Additionally, its presence in traditional medicine highlights its historical significance and potential therapeutic applications. However, further studies are necessary to fully elucidate its mechanisms of action and efficacy in clinical settings. As with many natural compounds, the specific characteristics, including solubility and stability, can vary based on environmental conditions and the method of extraction.

Formula: C₂₄H₃₀O₁₄

InChI: InChI=1S/C24H30O14/c1-3-11-12(4-5-35-21(32)10-6-14(26)17(28)15(27)7-10)13(22(33)34-2)9-36-23(11)38-24-20(31)19(30)18(29)16(8-25)37-24/h3,6-7,9,11-12,16,18-20,23-31H,1,4-5,8H2,2H3

InChI key: InChIKey=SMTKSCGLXONVGL-UHFFFAOYSA-N

SMILES: C(COC(=O)C1=CC(O)=C(O)C(O)=C1)C2C(C=C)C(OC3OC(CO)C(O)C(O)C3O)OC=C2C(OC)=O

Synonyms:

• 2H-Pyran-5-carboxylic acid, 3-ethenyl-2-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-3,4-dihydro-4-[2-[(3,4,5-trihydroxybenzoyl)oxy]ethyl]-, methyl ester, (2S,3R,4S)-
• 2H-Pyran-5-carboxylic acid, 3-ethenyl-2-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-3,4-dihydro-4-[2-[(3,4,5-trihydroxybenzoyl)oxy]ethyl]-, methyl ester, [2S-(2α,3β,4β)]-
• Cornuside I
• Methyl (2R,3S,4R)-3-ethenyl-4-[2-(3,4,5-trihydroxybenzoyl)oxyethyl]-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydro-2H-pyran-5-carboxylate
• methyl (2R,3S,4R)-3-ethenyl-2-(beta-D-glucopyranosyloxy)-4-{2-[(3,4,5-trihydroxybenzoyl)oxy]ethyl}-3,4-dihydro-2H-pyran-5-carboxylate
• 2H-Pyran-5-carboxylic acid, 3-ethenyl-2-(β-D-glucopyranosyloxy)-3,4-dihydro-4-[2-[(3,4,5-trihydroxybenzoyl)oxy]ethyl]-, methyl ester, [2S-(2α,3β,4β)]-
• Cornuside
• 2H-Pyran-5-carboxylic acid, 3-ethenyl-2-(β-D-glucopyranosyloxy)-3,4-dihydro-4-[2-[(3,4,5-trihydroxybenzoyl)oxy]ethyl]-, methyl ester, (2S,3R,4S)-

Comuside

CAS: 131189-57-6

Comuside

Formula: C₂₄H₃₀O₁₄

Purity: 99%

Molecular weight: 542.48659

Ref: 54-BISN0277

Cornuside

CAS: 131189-57-6

Formula: C₂₄H₃₀O₁₄

Molecular weight: 542.49

Ref: 7W-GK2384

Cornuside

CAS: 131189-57-6

Cornuside

Formula: C₂₄H₃₀O₁₄

Purity: ≥98%

Molecular weight: 542.49

Ref: 54-BUP08489

Comuside

CAS: 131189-57-6

Formula: C₂₄H₃₀O₁₄

Purity: 99%

Molecular weight: 542.4866

Ref: IN-DA000VNU

Cornuside (Standard)

CAS: 131189-57-6

Cornuside (Standard) is a reference standard for research and analysis in studies involving Cornuside. 1. Cornuside (Comuside) has immunomodulatory activity . 2. Cornuside suppresses expression levels of cytokine-induced proinflammatory and adhesion molecules in the human endothelial cells. 3. Cornuside can treat myocardial I/R and protect the liver from CCl4-induced acute hepatotoxicity, by reducing oxidative stress and suppressing inflammatory responses. 4. Cornuside has anti-inflammatory activity by downregulations of iNOS and COX-2 due to NF-κB inhibition as well as the negative regulation of ERK1/2, p38, and JNK1/2 phosphorylations in RAW 264.7 cells. 5. Cornuside has protective potential against cerebral ischemic injury, may be due to the suppression of intracellular Ca(2+) elevation and caspase-3 activity, and improvements in mitochondrial energy metabolism and antioxidant properties.

Formula: C₂₄H₃₀O₁₄

Molecular weight: 542.4866

Ref: TM-TMSM-2765

Cornuside

CAS: 131189-57-6

Formula: C₂₄H₃₀O₁₄

Purity: 95%~99%

Molecular weight: 542.49

Ref: BP-BP0394

Cornuside

CAS: 131189-57-6

Cornuside boosts immunity, reduces inflammation, protects heart and liver, and guards against brain injury by modulating stress responses.

Formula: C₂₄H₃₀O₁₄

Purity: 99.86% - >99.99%

Color and Shape: Solid

Molecular weight: 542.4866

Ref: TM-T4S2326

Cornuside

CAS: 131189-57-6

(2S,3R,4S)-3-Ethenyl-2-(β-D-glucopyranosyloxy)-3,4-dihydro-4-[2-[(3,4,5-trihydroxybenzoyl)oxy]ethyl]-2H-pyran-5-carboxylic acid methyl ester

Formula: C₂₄H₃₀O₁₄

Purity: 99%

Molecular weight: 542.49

Ref: IN-DG01301000

Cornuside

CAS: 131189-57-6

Natural glycoside

Formula: C₂₄H₃₀O₁₄

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 542.49

Ref: 5G-83331

Cornuside

CAS: 131189-57-6

Cornuside is a natural compound that is found in the fruits of Cornus. It is a dihydrochalcone, which has been shown to have hypoglycemic effects and inhibit the activity of 5-hmf. Cornuside also inhibits the enzyme activities involved in energy metabolism, such as glucose-6-phosphate dehydrogenase and hexokinase. It has also been shown to have genotoxic properties and induce DNA damage. Cornuside may be useful for treating diabetes or cancer, but further research needs to be done before this can be confirmed.

Formula: C₂₄H₃₀O₁₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 542.49 g/mol

Ref: 3D-MC33273

Cornuside

CAS: 131189-57-6

Formula: C₂₄H₃₀O₁₄

Molecular weight: 542.5

Ref: BE-RMT12842