CAS 133-67-5: Trichlormethiazide

Description: Trichlormethiazide is a thiazide diuretic commonly used in the treatment of hypertension and edema associated with various medical conditions. It is characterized by its chemical formula, which includes chlorine and sulfur atoms, contributing to its pharmacological properties. The compound works by inhibiting sodium reabsorption in the distal convoluted tubules of the kidneys, leading to increased urine output and decreased blood volume. Trichlormethiazide is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing in many cases. Its solubility in water is limited, which can affect its absorption and bioavailability. The substance may also exhibit side effects, including electrolyte imbalances, particularly hypokalemia, and should be used with caution in patients with renal impairment. Overall, trichlormethiazide is an important medication in the management of cardiovascular conditions, and its efficacy is enhanced when used in conjunction with other antihypertensive agents.

Formula: C₈H₈Cl₃N₃O₄S₂

InChI: InChI=1S/C8H8Cl3N3O4S2/c9-3-1-4-6(2-5(3)19(12,15)16)20(17,18)14-8(13-4)7(10)11/h1-2,7-8,13-14H,(H2,12,15,16)

InChI key: InChIKey=LMJSLTNSBFUCMU-UHFFFAOYSA-N

SMILES: O=S(=O)(N)C=1C=C2C(=CC1Cl)NC(NS2(=O)=O)C(Cl)Cl

Synonyms:

• 3-Dichloromethyl-6-chloro-7-sulfamoyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide
• 3-Dichloromethyl-6-chloro-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide
• 3-Dichloromethylhydrochlorothiazide
• 6-Chloro-3-(dichloromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• 6-Chloro-3-(dichloromethyl)-3,4-dihydro-7-sulfamyl-1,2,4-benzothiadiazine-1,1-dioxide
• 6-Chloro-3-dichloromethyl-3, 4-dihydro-2H-1, 2, 4-benzothiadiazine-7-sulfonamide-1, 1-dioxide
• 6-Chloro-3-dichloromethyl-3,4-dihydro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
• Achletin
• Anatran
• Anistadin
• Aponorin
• Carvacron
• Ciba 7057-Su
• Diurazida
• Diurese
• Diuroral
• Esmarin
• Fluitran
• Flurese
• Flutra
• Gangesol
• Hydrotrichlorothiazide
• Intromene
• Kubacron
• Metahydrin
• Metatensin
• Nakva
• Naqua
• Naquasone
• Naquival
• Nsc 61560
• Salirom
• Tachionin
• Tolcasone
• Trichlormetazid
• Trichlormethiazid
• Trichlormethiazide
• Trichloromethiazide
• Triclormetiazida
• Triflumen
• 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(dichloromethyl)-3,4-dihydro-, 1,1-dioxide

Trichloromethiazide

CAS: 133-67-5

• Formula: C₈H₈Cl₃N₃O₄S₂
• Purity: >99.0%(T)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 380.64

Trichlormethiazide

CAS: 133-67-5

Sulfonamides used as drugs

• Formula: C₈H₈Cl₃N₃O₄S₂
• Color and Shape: White Powder
• Molecular weight: 380.67 g/mol

TRICHLORMETHIAZIDE

CAS: 133-67-5

• Formula: C₈H₈Cl₃N₃O₄S₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 380.6558

Trichlormethiazide

CAS: 133-67-5

Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide …

• Formula: C₈H₈Cl₃N₃O₄S₂
• Purity: 98.80% - 99.54%
• Color and Shape: Solid
• Molecular weight: 380.66

Trichlormethiazide

CAS: 133-67-5

• Purity: 98%
• Molecular weight: 380.66g/mol

Trichlormethiazide

CAS: 133-67-5

• Formula: C₈H₈Cl₃N₃O₄S₂
• Molecular weight: 380.64

Trichlormethiazide

CAS: 133-67-5

• Formula: C₈H₈Cl₃N₃O₄S₂
• Color and Shape: Neat
• Molecular weight: 380.66

Trichlormethiazide

CAS: 133-67-5

• Formula: C₈H₈Cl₃N₃O₄S₂
• Color and Shape: Neat
• Molecular weight: 380.66

Trichlormethiazide RS

CAS: 133-67-5

• Color and Shape: White Solid Powder

Trichlormethiazide

CAS: 133-67-5

Applications Trichlormethiazide, is a diuretic, having similar properties as Hydrochlorothiazide (H714560). It is used for …

• Formula: C₈H₈Cl₃N₃O₄S₂
• Color and Shape: Neat
• Molecular weight: 380.66

Trichloromethiazide

CAS: 133-67-5

Trichloromethiazide is a hypoglycemic drug that lowers the blood glucose level by inhibiting the activity …

• Formula: C₈H₈Cl₃N₃O₄S₂
• Purity: Min. 95%
• Molecular weight: 380.64 g/mol