CAS 13392-28-4

Rimantadine

Description:

Rimantadine is an antiviral medication primarily used for the prevention and treatment of influenza A virus infections. It belongs to the class of adamantane derivatives and functions by inhibiting the viral replication process. The chemical structure of rimantadine features a bicyclic amine, which contributes to its mechanism of action by interfering with the uncoating of the virus within host cells. Rimantadine is known for its oral bioavailability and is metabolized in the liver, with a relatively long half-life, allowing for less frequent dosing. Common side effects may include gastrointestinal disturbances and central nervous system effects, such as dizziness or insomnia. It is important to note that rimantadine's effectiveness can be compromised due to the emergence of resistant viral strains, which has led to decreased usage in some regions. As with any antiviral treatment, it is essential to consider the specific strain of the virus and local resistance patterns when prescribing rimantadine.

Formula: C₁₂H₂₁N

InChI: InChI=1S/C12H21N/c1-8(13)12-5-9-2-10(6-12)4-11(3-9)7-12/h8-11H,2-7,13H2,1H3

InChI key: InChIKey=UBCHPRBFMUDMNC-UHFFFAOYSA-N

SMILES: C(C)(N)C12CC3CC(C1)CC(C2)C3

Synonyms:

• 1-(1-Adamantyl)-ethylamine
• 1-(1-Adamantyl)ethanamine
• 1-(1-Aminoethyl)adamantane
• 1-(Adamantan-1-yl)ethan-1-amine
• 1-(Adamantan-1-yl)ethanamine
• 1-(Tricyclo[3.3.1.1~3,7~]Dec-1-Yl)Ethanamine
• 1-Adamantanemethylamine, α-methyl-
• 1-Adamantanethylamine
• 1-Rimantadine
• 2-(Tricyclo[3.3.1.1~3,7~]Dec-1-Yl)Ethanamine
• Algirem
• Tricyclo[3.3.1.1^3,7]decane-1-methanamine, α-methyl-
• α-Methyl-1-adamantanemethylamine
• α-Methyltricyclo[3.3.1.1^3,7]decane-1-methanamine
• Rimantadine
• Tricyclo[3.3.1.13,7]decane-1-methanamine, α-methyl-

1-(1-Adamantyl)ethylamine Hydrochloride

CAS: 13392-28-4, 1501-84-4

Formula: C₁₂H₂₁N·HCl

Purity: >98.0%(N)(NMR)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 215.77

Ref: 3B-R0070

Rimantadine

CAS: 13392-28-4

Rimantadine (1-Rimantadine) (Flumadine) is an anti-influenza virus drug for T. brucei with IC50 of 7 μM.

Formula: C₁₂H₂₁N

Purity: 98%

Color and Shape: Solid

Molecular weight: 179.3

Ref: TM-T6642

Rimantadine

CAS: 13392-28-4

Formula: C₁₂H₂₁N

Molecular weight: 179.30

Ref: 7W-GP4071

1-Adamantaneethylamine

CAS: 13392-28-4

1-Adamantaneethylamine

Purity: ≥95%

Molecular weight: 179.30g/mol

Ref: 54-OR315791

1-(1-Adamantyl)ethylamine

CAS: 13392-28-4

1-(1-Adamantyl)ethylamine is an antipyretic drug that belongs to the class of nonsteroidal anti-inflammatory drugs. It has been shown to inhibit the inflammatory response by inhibiting prostaglandin synthesis and reducing leukocyte accumulation in inflamed tissues. 1-(1-Adamantyl)ethylamine has been used as a treatment for infectious diseases and influenza, including pandemic influenza. It is currently being studied as a potential antiviral against HIV, SARS, and influenza A viruses. This drug also inhibits viral replication by blocking the binding of the virus to host cells and interfering with viral protein synthesis. The drug may be active against certain strains of influenza that are resistant to other antivirals such as rimantadine or amantadine.

Formula: C₁₂H₂₁N

Purity: Min. 95%

Molecular weight: 179.3 g/mol

Ref: 3D-FA07666

1-(1-adamantyl)ethanamine hydrochloride

CAS: 13392-28-4

Formula: C₁₂H₂₂ClN

Purity: 97.0%

Color and Shape: Solid

Molecular weight: 215.77

Ref: 10-F358016

1-(1-Adamantyl)ethylamine

CAS: 13392-28-4

Formula: C₁₂H₂₁N

Molecular weight: 179.31

Ref: ST-EA-CP-A73015