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CAS 13392-28-4

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Rimantadine

Description:
Rimantadine is an antiviral medication primarily used for the prevention and treatment of influenza A virus infections. It belongs to the class of adamantane derivatives and functions by inhibiting the viral replication process. The chemical structure of rimantadine features a bicyclic amine, which contributes to its mechanism of action by interfering with the uncoating of the virus within host cells. Rimantadine is known for its oral bioavailability and is metabolized in the liver, with a relatively long half-life, allowing for less frequent dosing. Common side effects may include gastrointestinal disturbances and central nervous system effects, such as dizziness or insomnia. It is important to note that rimantadine's effectiveness can be compromised due to the emergence of resistant viral strains, which has led to decreased usage in some regions. As with any antiviral treatment, it is essential to consider the specific strain of the virus and local resistance patterns when prescribing rimantadine.
Formula:C12H21N
InChI:InChI=1S/C12H21N/c1-8(13)12-5-9-2-10(6-12)4-11(3-9)7-12/h8-11H,2-7,13H2,1H3
InChI key:InChIKey=UBCHPRBFMUDMNC-UHFFFAOYSA-N
SMILES:C(C)(N)C12CC3CC(C1)CC(C2)C3
Synonyms:
  • 1-(1-Adamantyl)-ethylamine
  • 1-(1-Adamantyl)ethanamine
  • 1-(1-Aminoethyl)adamantane
  • 1-(Adamantan-1-yl)ethan-1-amine
  • 1-(Adamantan-1-yl)ethanamine
  • 1-(Tricyclo[3.3.1.1~3,7~]Dec-1-Yl)Ethanamine
  • 1-Adamantanemethylamine, α-methyl-
  • 1-Adamantanethylamine
  • 1-Rimantadine
  • 2-(Tricyclo[3.3.1.1~3,7~]Dec-1-Yl)Ethanamine
  • See more synonyms
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