CAS 134523-03-8: Atorvastatin Calcium
Description:Atorvastatin Calcium is a pharmaceutical compound primarily used as a lipid-lowering agent to manage hyperlipidemia and reduce the risk of cardiovascular disease. It belongs to the class of drugs known as statins, which function by inhibiting the enzyme HMG-CoA reductase, a key player in cholesterol biosynthesis in the liver. This action leads to a decrease in low-density lipoprotein (LDL) cholesterol and triglycerides while increasing high-density lipoprotein (HDL) cholesterol levels. Atorvastatin is typically administered orally and is well-absorbed in the gastrointestinal tract. Its solubility is influenced by pH, with better solubility in acidic conditions. The compound is characterized by its molecular formula, which reflects its complex structure, and it exists as a calcium salt to enhance its stability and bioavailability. Common side effects may include muscle pain, liver enzyme alterations, and gastrointestinal disturbances. As with all medications, atorvastatin should be used under medical supervision, considering potential interactions with other drugs and individual patient health profiles.
Formula:C33H35FN2O5Ca
InChI:InChI=1S/C33H35FN2O5.Ca/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40;/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40);/t26-,27-;/m1./s1
InChI key:InChIKey=BWFCZHDTTAYGNN-CNZCJKERSA-N
SMILES:[Ca].O=C(O)CC(O)CC(O)CCN1C(C=2C=CC(F)=CC2)=C(C=3C=CC=CC3)C(C(=O)NC=4C=CC=CC4)=C1C(C)C
- Synonyms:
- (3R,5R)-7-[2-(4-Fluorophenyl)-5-Isopropyl-3-Phenyl-4-(Pheynylcarbamoyl)Pyrrol-1-yl]-3,5-Dihydroheptanoic Acid,calcium salt
- (3R,5R)-7-[2-(4-Fluorophenyl)-5-Isopropyl-3-Phenyl-4-(Pheynylcarbamoyl)Pyrrol-1-yl]-3,5�CDihydroheptanoic Acid,calcium salt
- (3R,5R)-7-[2-(4-Fluorophenyl)-5-Isopropyl-3-Phenyl-4-(Pheynylcarbamoyl)Pyrrol-1-yl]-3,5�CDihydroheptanoic Acid,calcium salt(L-4)
- (R-(R*,R*))-, Atorvastatin calcium
- 1H-Pyrrole-1-Heptanoicacid,Beta,Delta-Dihydroxy-2-(4-Fluorophenyl)-5-(1-Methy Calciumsalt(2:1),(R-(R*,R*))-Lethyl)-3-Phenyl-4-((Phenylamino)Carbonyl)
- 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-calcium salt (2: 1), (R-(R*,R*))-
- 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, calcium salt (2:1), (βR,δR)-
- 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, calcium salt (2:1), [R-(R*,R*)]-
- 1H-Pyrrole-1-heptanoic acid,beta,delta-dihydroxy-2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-calcium salt (2: 1)
- Atocor
- See more synonyms
- Atoraz
- Atorvastatin Ca
- Atorvastatin Calcium Anhydrous
- Atorvastatin Calsium
- Atorvastatin calcium (USAN)
- Atorvastatin calcium salt
- Atorvastatin hemicalcium
- Atorvastatin hemicalcium salt
- Atorvastatincalcuim
- Beta,Delta-Dihydroxy-2-(4-Fluorophenyl)-5-(1-Methylethyl)-3-Phenyl-4-((Phenylamino)Carbonyl)-Calcium Salt(2:1)
- C08078
- Calcium (betaR,deltaR)-2-(p-fluorophenyl)-beta,delta-dihydroxy-5-isopr opyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoate (1:2)
- Ci-981
- D00887
- Delta-Dihydroxy-2-(4-Fluorophenyl)-5-(1-Methylethyl)-3-Phenyl-4-((Phenylamino)Carbonyl)-Betcalci1H-Pyrrole-1-Heptanoicaci
- Drg-0321
- L-4
- Lipibec
- Lipitor
- Lipitor (TN)
- Lorvast
- Lowlip
- Ls-136974
- Pd 134298-38A
- Pd134298-38A
- Prevencor
- Rotacor
- Sortis
- Storvas
- Tahor
- Torvast
- Ym-548
- [R-(R*, R*)]-7-[2-(4-Fluorophenyl)-5-(1-Methylethyl)-3-Phenyl-4-(Phenylaminocarbonyl)-1H-Pyrrol-1-Yl]-3,5-Dihydroxy-Heptanoic Acid Calcium Salt
- calcium (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-p ropan-2-yl-pyrrol-1-yl]-3,5-dihydroxy-heptanoate
- Atorvastatin calcium
