CAS 137201-62-8: spinorphin
Description:Spinorphin is a peptide that functions as an endogenous opioid, primarily known for its role in modulating pain and stress responses in the body. It is derived from the proenkephalin precursor and exhibits a high affinity for opioid receptors, particularly the delta and mu receptors. This characteristic allows spinorphin to influence analgesic pathways, potentially providing pain relief and contributing to the body's natural pain management system. The peptide is notable for its ability to inhibit the activity of enkephalin-degrading enzymes, thereby prolonging the effects of enkephalins, which are naturally occurring peptides that also bind to opioid receptors. Spinorphin's structure includes a sequence of amino acids that contribute to its biological activity, and its interactions with the nervous system highlight its importance in neurobiology and pharmacology. Research into spinorphin may offer insights into new therapeutic approaches for pain management and the treatment of opioid-related disorders.
Formula:C45H64N8O10
InChI:InChI=1/C45H64N8O10/c1-23(2)19-31(46)39(56)50-37(25(5)6)43(60)51-36(24(3)4)42(59)49-34(20-27-14-16-29(55)17-15-27)44(61)53-18-10-13-35(53)41(58)48-33(40(57)52-38(26(7)54)45(62)63)21-28-22-47-32-12-9-8-11-30(28)32/h8-9,11-12,14-17,22-26,31,33-38,47,54-55H,10,13,18-21,46H2,1-7H3,(H,48,58)(H,49,59)(H,50,56)(H,51,60)(H,52,57)(H,62,63)/t26-,31+,33+,34+,35+,36+,37+,38+/m1/s1
- Synonyms:
- Leu-val-val-tyr-pro-trp-thr
- Leucyl-valyl-valyl-tyrosyl-prolyl-tryptophyl-threonine
- L-Threonine, N-(N-(1-(N-(N-(N-L-leucyl-L-valyl)-L-valyl)-L-tyrosyl)-L-prolyl)-L-tryptophyl)-
- L-leucyl-L-valyl-L-valyl-L-tyrosyl-L-prolyl-L-tryptophyl-L-threonine
