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CAS 13739-02-1

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diacerein

Description:
Diacerein is a chemical compound primarily recognized for its use as a pharmaceutical agent, particularly in the treatment of osteoarthritis. It is classified as an anthraquinone derivative and exhibits anti-inflammatory and analgesic properties. Diacerein functions as a selective inhibitor of interleukin-1, which plays a significant role in the inflammatory process associated with joint diseases. The compound is typically administered in its diacetylated form and is known for its relatively slow onset of action, often taking several weeks to achieve therapeutic effects. In terms of solubility, diacerein is moderately soluble in organic solvents but has limited solubility in water, which can affect its bioavailability. Its chemical structure includes a hydroxyl group and two acetyl groups, contributing to its pharmacological activity. While generally well-tolerated, diacerein may cause gastrointestinal side effects in some patients. Overall, its unique mechanism of action and therapeutic benefits make it a valuable option in managing chronic inflammatory conditions.
Formula:C19H12O8
InChI:InChI=1/C19H12O8/c1-8(20)26-13-5-3-4-11-15(13)18(23)16-12(17(11)22)6-10(19(24)25)7-14(16)27-9(2)21/h3-7H,1-2H3,(H,24,25)
InChI key:InChIKey=TYNLGDBUJLVSMA-UHFFFAOYSA-N
SMILES:O(C(C)=O)C1=C2C(C(=O)C=3C(C2=O)=C(OC(C)=O)C=CC3)=CC(C(O)=O)=C1
Synonyms:
  • 1,8-Diacetoxy-3-carboxyanthraquinone
  • 2-Anthracenecarboxylic acid, 4,5-bis(acetyloxy)-9,10-dihydro-9,10-dioxo-
  • 2-Anthroic acid, 9,10-dihydro-4,5-dihydroxy-9,10-dioxo-, diacetate
  • 4,5-Bis(Acetyloxy)-9,10-Dioxo-9,10-Dihydroanthracene-2-Carboxylic Acid
  • 4,5-Bis(acetyloxy)-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic acid
  • 4,5-Bis(acetyloxy)-9,10-dioxo-2-anthracenecarboxylic acid
  • 4,5-Diacetoxy-9,10-dioxoanthracene-2-carboxylic acid
  • 4,5-Diacetoxyanthraquinone-2-carboxylic acid
  • 4,5-Diacetylrhein
  • Ac 201
  • See more synonyms
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