CAS 1399177-37-7

Formula: C27H29N5O

InChI: InChI=1S/C27H29N5O/c1-17-14-24(22-4-3-5-22)25(26-29-18(2)30-31-26)15-23(17)27(33)32-12-10-21(11-13-32)20-8-6-19(16-28)7-9-20/h6-9,14-15,21-22H,3-5,10-13H2,1-2H3,(H,29,30,31)

InChI key: BBGOSBDSLYHMRA-UHFFFAOYSA-N

SMILES: CC1=CC(=C(C=C1C(=O)N2CCC(CC2)C3=CC=C(C=C3)C#N)C4=NNC(=N4)C)C5CCC5

Denifanstat

CAS: 1399177-37-7

Denifanstat (FASN-IN-2) is a FASN inhibitor with selective and oral activity. Denifanstat has been used in studies of steatohepatitis. Cost effective and quality assured.

Formula: C₂₇H₂₉N₅O

Purity: 98.33% - 99.35%

Color and Shape: Solid

Molecular weight: 439.55

Ref: TM-T15271

4-(1-(4-Cyclobutyl-2-methyl-5-(3-methyl-1H-1,2,4-triazol-5-yl)benzoyl)piperidin-4-yl)benzonitrile

CAS: 1399177-37-7

Formula: C₂₇H₂₉N₅O

Purity: 98%

Color and Shape: Solid

Molecular weight: 439.5521

Ref: IN-DA01FY71

Denifanstat

CAS: 1399177-37-7

Denifanstat

Formula: C₂₇H₂₉N₅O

Purity: ≥98%

Molecular weight: 439.55

Ref: 54-BUP12571

Denifanstat

CAS: 1399177-37-7

4-(1-(4-Cyclobutyl-2-methyl-5-(3-methyl-1H-1,2,4-triazol-5-yl)benzoyl)piperidin-4-yl)benzonitrile

Formula: C₂₇H₂₉N₅O

Purity: 98%

Molecular weight: 439.55

Ref: IN-DG01141181

FASN-IN-2

CAS: 1399177-37-7

FASN-IN-2 is a chemical inhibitor, specifically targeting fatty acid synthase (FASN), a key enzyme involved in lipogenesis. It is derived from synthetic chemical methods and engineered to interfere with the enzymatic function of FASN by binding to its active site, thereby preventing the conversion of acetyl-CoA and malonyl-CoA to fatty acids. This inhibition is crucial as FASN is overexpressed in various cancer cells, contributing to their rapid proliferation and survival by providing necessary lipids for membrane synthesis.

Formula: C₂₇H₂₉N₅O

Purity: Min. 95%

Molecular weight: 439.6 g/mol

Ref: 3D-ZFC17737