CAS 145672-81-7

N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-, acetate (salt)

Description:

N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-, acetate (salt), with CAS number 145672-81-7, is a complex synthetic peptide that exhibits a range of characteristics typical of peptide compounds. It is likely to be a white to off-white solid, soluble in polar solvents such as water and methanol, and may have limited solubility in non-polar solvents. The presence of various amino acid residues suggests potential biological activity, possibly as a pharmaceutical agent or research compound. Its structure includes multiple chiral centers, indicating that it may exhibit stereospecific properties. The acetate salt form implies enhanced stability and solubility, which is beneficial for formulation in biological studies. As with many peptides, it may be sensitive to hydrolysis and degradation under certain conditions, necessitating careful handling and storage. Overall, this compound's unique structure and functional groups suggest potential applications in medicinal chemistry and biochemistry.

Formula: C₇₀H₉₂ClN₁₇O₁₄xC₂H₄O₂

InChI: InChI=1/C70H92ClN17O14.C2H4O2/c1-39(2)31-52(61(94)82-51(15-9-28-77-69(73)74)68(101)88-30-10-16-58(88)67(100)79-40(3)59(72)92)83-60(93)50(14-8-29-78-70(75)102)81-63(96)54(34-43-20-25-49(91)26-21-43)86-66(99)57(38-89)87-65(98)56(36-45-11-7-27-76-37-45)85-64(97)55(33-42-18-23-48(71)24-19-42)84-62(95)53(80-41(4)90)35-44-17-22-46-12-5-6-13-47(46)32-44;1-2(3)4/h5-7,11-13,17-27,32,37,39-40,50-58,89,91H,8-10,14-16,28-31,33-36,38H2,1-4H3,(H2,72,92)(H,79,100)(H,80,90)(H,81,96)(H,82,94)(H,83,93)(H,84,95)(H,85,97)(H,86,99)(H,87,98)(H4,73,74,77)(H3,75,78,102);1H3,(H,3,4)/t40-,50-,51+,52+,53-,54-,55+,56-,57-,58?;/m1./s1

Cetrorelix (acetate)

CAS: 145672-81-7

Formula: C₇₂H₉₆ClN₁₇O₁₆

Purity: 99%

Color and Shape: Solid

Molecular weight: 1491.0899

Ref: IN-DA001D9O

Cetrorelix acetate

CAS: 145672-81-7

Formula: C₇₀H₉₂ClN₁₇O₁₄·xC₂H₄O₂

Molecular weight: 1431.04 (free base

Ref: 7W-GK0758

Cetrorelix Acetate

Controlled Product

CAS: 145672-81-7

Applications Cetrorelix acetate is an gonadotropin-releasing hormone antagonist and is used to treat hormone-sensitive cancers of the prostate and breast.
References Hosseini, M.A., et al.: Gynecol. Endocrinol., 28, 853 (2012); Rashidi, B., et al.: Iran. J. Reprod. Med., 9, 315 (2011); Wiser, A., et al.: Open. J. Obstetics. Gynecol., 1, 31 (2011);

Formula: C₇₀H₉₂ClN₁₇O₁₄·C₂H₄O₂

Color and Shape: White To Off-White

Molecular weight: 1491.09

Ref: TR-C281500

Cetrorelix Acetate

CAS: 145672-81-7

Cetrorelix Acetate is gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM.

Formula: C₇₀H₉₂ClN₁₇O₁₄·xC₂H₄O₂

Purity: 97.96%

Color and Shape: Solid

Molecular weight: 1491.11

Ref: TM-T5520

Cetrorelix Acetate

Controlled Product

CAS: 145672-81-7

Cetrorelix acetate is a peptide that belongs to the group of group p2. It has been used in an experimental model as a treatment for metabolic disorders. Cetrorelix acetate has been shown to be an antagonist for the luteinizing hormone receptor (LHR), which leads to decreased levels of testosterone and increases in luteinizing hormone. Cetrorelix acetate also blocks the release of follicle-stimulating hormone from the anterior pituitary gland, leading to reduced levels of progesterone and estradiol. This drug has been shown to have pro-apoptotic effects on testicular cells in rats, as well as chemiluminescent properties. The injection solution contains cetrorelix acetate, trifluoroacetic acid, and histological analysis reagents.

Formula: C₇₀H₉₂ClN₁₇O₁₄·C₂H₄O₂

Purity: Min. 95%

Molecular weight: 1,491.11 g/mol

Ref: 3D-VFA67281