CAS 146982-27-6

N(alpha)-fmoc-N(epsilon)-alloc-L-lysine

Description:

N(alpha)-Fmoc-N(epsilon)-alloc-L-lysine is a derivative of the amino acid lysine, modified to enhance its utility in peptide synthesis and other biochemical applications. The "Fmoc" (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino terminus, allowing for selective reactions without interfering with the lysine's reactivity. The "alloc" (allyloxycarbonyl) group protects the epsilon amino group, providing a means for subsequent deprotection and functionalization. This compound is typically used in solid-phase peptide synthesis, where the protection of functional groups is crucial for the stepwise assembly of peptides. Its structure allows for the introduction of various side chains and modifications, making it versatile in the design of peptides with specific properties. The presence of both Fmoc and alloc groups enables chemists to manipulate the molecule's reactivity and stability under different conditions. Overall, N(alpha)-Fmoc-N(epsilon)-alloc-L-lysine is a valuable building block in the field of peptide chemistry, facilitating the synthesis of complex peptides and proteins.

Formula: C₂₅H₂₈N₂O₆

InChI: InChI=1/C25H28N2O6/c1-2-15-32-24(30)26-14-8-7-13-22(23(28)29)27-25(31)33-16-21-19-11-5-3-9-17(19)18-10-4-6-12-20(18)21/h2-6,9-12,21-22H,1,7-8,13-16H2,(H,26,30)(H,27,31)(H,28,29)/t22-/m0/s1

SMILES: C=CCOC(=NCCCC[C@@H](C(=O)O)N=C(O)OCC1c2ccccc2c2ccccc12)O

Synonyms:

• Fmoc-Lys(Aloc)-OH
• Fmoc-Lys(Alloc)-OH
• N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-N~6~-[(prop-2-en-1-yloxy)carbonyl]-L-lysine

N6-[(Allyloxy)carbonyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine

CAS: 146982-27-6

Formula: C₂₅H₂₈N₂O₆

Purity: >96.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 452.51

Ref: 3B-A3245

Nε-Allyloxycarbonyl-Nα-Fmoc-L-lysine, 95%

CAS: 146982-27-6

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₂₅H₂₈N₂O₆

Purity: 95%

Molecular weight: 452.51

Ref: 02-H63768

N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6-[(2-propen-1-yloxy)carbonyl]-L-lysine

CAS: 146982-27-6

Formula: C₂₅H₂₈N₂O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 452.4996

Ref: IN-DA0034Y3

Fmoc-Lys(Alloc)-OH

CAS: 146982-27-6

Fmoc-Lys(Alloc)-OH

Formula: C₂₅H₂₈N₂O₆

Purity: ≥98%

Molecular weight: 452.5

Ref: 54-BUP20248

Fmoc-Lys(Alloc)-OH

CAS: 146982-27-6

Fmoc-Lys(Alloc)-OH is a lysine derivative containing Fmoc protecting group, which can be used for peptide synthesis and drug design.

Formula: C₂₅H₂₈N₂O₆

Purity: 98.49%

Color and Shape: Solid

Molecular weight: 452.5

Ref: TM-T67629

Fmoc-Lys(Alloc)-OH

CAS: 146982-27-6

Formula: C₂₅H₂₈N₂O₆

Purity: ≥ 98.0%

Color and Shape: White powder or crystals

Molecular weight: 452.50

Ref: 7W-GM9940

Fmoc-Lys(Alloc)-OH

CAS: 146982-27-6

M06250 - Fmoc-Lys(Alloc)-OH

Formula: C₂₅H₂₈N₂O₆

Purity: 97%

Color and Shape: Solid, Beige powder

Molecular weight: 452.507

Ref: 10-M06250

Fmoc-Lys(Alloc)-OH

CAS: 146982-27-6

Fmoc-Lys(Alloc)-OH

Formula: C₂₅H₂₈N₂O₆

Purity: 98%

Molecular weight: 452.49

Ref: IN-DG9243

Fmoc-L-Lys(Alloc)-OH

CAS: 146982-27-6

Fmoc-L-Lys(Alloc)-OH is a peptide that consists of an amino acid sequence that is a variant of the human insulin molecule. The peptide has been modified to incorporate a pegyl group, which increases the serum stability of this drug and prevents enzymatic degradation. This compound has been tested in vitro by binding to nuclear DNA and inhibiting receptor binding. Fmoc-L-Lys(Alloc)-OH has also shown anticancer effects in vivo with tumor xenografts and apoptosis protein expression in human serum, as well as an increase in serine protease activity.

Formula: C₂₅H₂₈N₂O₆

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 452.5 g/mol

Ref: 3D-FF16395

Fmoc-Lys(Aloc)-OH

CAS: 146982-27-6

The selectively cleavable Alloc group allows on-resin modification of lysine side-chains during Fmoc-SPPS.

Formula: C₂₅H₂₈N₂O₆

Purity: 98.7%

Color and Shape: White

Molecular weight: 452.51

Ref: 01-4016656