CAS 147-24-0
:Diphenhydramine hydrochloride
Description:
Diphenhydramine hydrochloride is an antihistamine commonly used to relieve symptoms of allergy, hay fever, and the common cold. It is classified as a first-generation antihistamine, which means it can cross the blood-brain barrier, often leading to sedative effects. The chemical structure of diphenhydramine includes a diphenylmethanol moiety, contributing to its pharmacological properties. It acts primarily as an antagonist to the H1 histamine receptor, thereby reducing the effects of histamine in the body. In addition to its antihistaminic properties, diphenhydramine is also utilized as a short-term treatment for insomnia and as an adjunct in the management of motion sickness. The hydrochloride salt form enhances its solubility in water, making it suitable for various formulations, including tablets, capsules, and liquid preparations. Common side effects may include drowsiness, dizziness, dry mouth, and blurred vision. Due to its sedative properties, caution is advised when operating machinery or driving after consumption.
Formula:C17H21NO·ClH
InChI:InChI=1S/C17H21NO.ClH/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;/h3-12,17H,13-14H2,1-2H3;1H
InChI key:InChIKey=PCHPORCSPXIHLZ-UHFFFAOYSA-N
SMILES:C(OCCN(C)C)(C1=CC=CC=C1)C2=CC=CC=C2.Cl
Synonyms:- 2-(Benzhydryloxy)-N,N-dimethylethylamine hydrochloride
- 2-(diphenylmethoxy)-N,N-dimethylethanamine
- 2-(diphenylmethoxy)-N,N-dimethylethanamine hydrochloride (1:1)
- 2-Diphenylmethoxy-N,N-dimethylethylamine hydrochloride
- Alledryl
- Allergan
- Allergina
- Allergival
- Amidryl
- Asdrin
- Bagodryl
- Bax
- Bena
- Bena-Fedrin
- Benadril hydrochloride
- Benadryl
- Benison
- Benocten
- Benodine
- Benylin
- Benzantin
- Benzhydramine
- Benzhydramine hydrochloride
- Benzhydrol β-dimethylaminoethyl ether hydrochloride
- Denydryl
- Dibondrin
- Difenhidramina, Clorhidrato
- Difenhydramine hydrochloride
- Dimedrol
- Dimedrol hydrochloride
- Dimedrolum
- Diphantine
- Diphenhydramine HCl
- Diphenhydramine hydrochlorids
- Diphenhydramine, Chlorhydrate
- Diphenhydraminhydrochlorid
- Ethanamine, 2-(diphenylmethoxy)-N,N-dimethyl-, hydrochloride
- Ethanamine, 2-(diphenylmethoxy)-N,N-dimethyl-, hydrochloride (1:1)
- Ethylamine, 2-(diphenylmethoxy)-N,N-dimethyl-, hydrochloride
- Fenylhist
- Halbmond
- Histacyl
- N-(2-Diphenylmethoxyethyl)-N,N-dimethylamine hydrochloride
- Noctomin
- Psilo-Balsam
- Resmin
- Restamin
- S 8
- Sedopretten
- Sekundal D
- Syntedril
- Theraflu
- Vena
- Wehydryl
- [2-(Diphenylmethoxy)ethyl]dimethylamine hydrochloride
- See more synonyms
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Diphenhydramine
CAS:Formula:C17H21NOPurity:>98.0%(GC)(T)Color and Shape:Colorless to Yellow clear liquidMolecular weight:255.36Diphenhydramine Hydrochloride
CAS:Formula:C17H21NO·HClPurity:>98.0%(T)(HPLC)Color and Shape:White powder to crystalMolecular weight:291.82Diphenhydramine Hydrochloride 1.0 mg/ml in Methanol (as free base)
CAS:Color and Shape:Single SolutionDIPHENHYDRAMINE HYDROCHLORIDE CRS
CAS:<p>DIPHENHYDRAMINE HYDROCHLORIDE CRS</p>Formula:C17H22ClNOColor and Shape:Crystalline Powder. White. Whitish. Powder.Molecular weight:291.8157Diphenhydramine hydrochloride
CAS:Diphenhydramine hydrochlorideFormula:C17H21NOHClPurity:99.6%Color and Shape:White To Off-WhiteMolecular weight:291.13899Diphenhydramine Hydrochloride
CAS:Aromatic drugs of amino-alcohols, other than those contg more than one kind of oxygen function, their ethers and esters; salts thereof, nesoiFormula:C17H21NO·HClColor and Shape:White PowderMolecular weight:291.82N-(2-Diphenylmethoxyethyl)-N,N-Dimethylamine Hydrochloride
CAS:Formula:C17H22ClNOPurity:98%Color and Shape:SolidMolecular weight:291.8157N-(2-Diphenylmethoxyethyl)-N,N-Dimethylamine Hydrochloride
CAS:<p>N-(2-Diphenylmethoxyethyl)-N,N-Dimethylamine Hydrochloride</p>Purity:99%+Molecular weight:291.82g/molDiphenhydramine hydrochloride
CAS:Diphenhydramine hydrochloridePurity:≥98%Molecular weight:291.82g/molDiphenhydramine HCl
CAS:Formula:C17H21NO·HClColor and Shape:White To Off-White SolidMolecular weight:255.36 36.46Diphenhydramine hydrochloride
CAS:<p>DPH: antihistamine for cough, nausea, itching, allergy, Parkinson's, sleep aid, cold remedy.</p>Formula:C17H22ClNOPurity:99.84%Color and Shape:Taste Ph (5% Aqueous Solution) 4-6 (Ntp 1992)Molecular weight:291.82Diphenhydramine hydrochloride 100 µg/mL in Acetonitrile
CAS:Controlled ProductFormula:C17H21NO·ClHColor and Shape:Single SolutionMolecular weight:291.82Diphenhydramine hydrochloride
CAS:Formula:C17H21NO·HClPurity:≥ 98.0%Color and Shape:White powderMolecular weight:291.82Diphenhydramine Hydrochloride
CAS:<p>Stability Hygroscopic<br>Applications Diphenhydramine is an H1-histamine receptor antagonist. Diphenhydramine is categorized as an antihistaminic; sedative, hypnotic.<br>References Gruhzit, O.M., et al.: J. Pharmacol. Exp. Ther., 89, 227 (1947), Holcomb, I.J., et al.: Anal. Profiles Drug Subs., 3, 173 (1974), Scavone, J.M., et al.: J. Clin. Pharmacol., 38, 603 (1998),<br></p>Formula:C17H21NO·ClHColor and Shape:White SolidMolecular weight:291.82Diphenhydramine hydrochloride
CAS:Controlled Product<p>Diphenhydramine is a first-generation antihistamine that crosses the blood-brain barrier and blocks the histamine H1 receptor. It has been used in the treatment of allergic reactions and bowel disease. The drug has shown no significant adverse effects in humans at doses up to 100 mg/day. Diphenhydramine is also used as an antiemetic, for motion sickness, and for other indications. It is available over the counter and by prescription. Side effects include dry mouth, blurred vision, constipation, difficulty urinating, and sleepiness. Diphenhydramine may interact with other drugs such as fructus (fruit) of Elaeagnus angustifolia (Russian olive), which can cause a decrease in blood pressure when taken together with diphenhydramine.</p>Formula:C17H21NO•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:291.82 g/mol
