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CAS 149676-40-4

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Pefloxacin

Description:
Pefloxacin is a synthetic fluoroquinolone antibiotic characterized by its broad-spectrum antibacterial activity. It is primarily effective against a variety of Gram-negative and some Gram-positive bacteria, making it useful in treating various infections, including those of the respiratory tract, urinary tract, and skin. The chemical structure of pefloxacin includes a bicyclic core with a fluorine atom, which enhances its potency and bioavailability. It is typically administered orally and is known for its relatively good absorption and distribution in the body. Pefloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and transcription, thereby preventing bacterial growth and reproduction. Common side effects may include gastrointestinal disturbances, central nervous system effects, and potential tendon damage, particularly in older adults. As with other antibiotics, the emergence of resistance is a concern, necessitating careful use and adherence to prescribed regimens. Overall, pefloxacin represents an important option in the arsenal against bacterial infections, although its use may be limited by safety considerations and resistance patterns.
Formula:C17H20FN3O3
InChI:InChI=1/C17H20FN3O3/c1-3-20-10-12(17(23)24)16(22)11-8-13(18)15(9-14(11)20)21-6-4-19(2)5-7-21/h8-10H,3-7H2,1-2H3,(H,23,24)
SMILES:CCn1cc(c(=O)c2cc(c(cc12)N1CCN(C)CC1)F)C(=O)O
Synonyms:
  • Rb-1589
  • Pefloxacine Mesylate Dihydrate
  • Pefloxacine Methansulfonate Dihydrate
  • Pefloxacin Mesylate Dihydrate
  • Pefloxacin Methanesulfonate
  • Pefloxacin Methane Sulfonate Dihydrate
  • Perfloxacine
  • 1-Ethyl-6-Fluoro-7-(4-Methylpiperazin-1-Yl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid
  • Pefloxacin Base
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Found 13 products.