CAS 149676-40-4: Pefloxacin

Description: Pefloxacin is a synthetic fluoroquinolone antibiotic characterized by its broad-spectrum antibacterial activity. It is primarily effective against a variety of Gram-negative and some Gram-positive bacteria, making it useful in treating various infections, including those of the respiratory tract, urinary tract, and skin. The chemical structure of pefloxacin includes a bicyclic core with a fluorine atom, which enhances its potency and bioavailability. It is typically administered orally and is known for its relatively good absorption and distribution in the body. Pefloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and transcription, thereby preventing bacterial growth and reproduction. Common side effects may include gastrointestinal disturbances, central nervous system effects, and potential tendon damage, particularly in older adults. As with other antibiotics, the emergence of resistance is a concern, necessitating careful use and adherence to prescribed regimens. Overall, pefloxacin represents an important option in the arsenal against bacterial infections, although its use may be limited by safety considerations and resistance patterns.

Formula: C₁₇H₂₀FN₃O₃

InChI: InChI=1/C17H20FN3O3/c1-3-20-10-12(17(23)24)16(22)11-8-13(18)15(9-14(11)20)21-6-4-19(2)5-7-21/h8-10H,3-7H2,1-2H3,(H,23,24)

Synonyms:

• Rb-1589
• Pefloxacine Mesylate Dihydrate
• Pefloxacine Methansulfonate Dihydrate
• Pefloxacin Mesylate Dihydrate
• Pefloxacin Methanesulfonate
• Pefloxacin Methane Sulfonate Dihydrate
• Perfloxacine
• 1-Ethyl-6-Fluoro-7-(4-Methylpiperazin-1-Yl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid
• Pefloxacin Base

Pefloxacine methanesulfonate dihydrate, 95%

CAS: 149676-40-4

A broad spectrum antibiotic that targets Gram-negative and -positive bacteria, and also some mycoplasma species …

• Formula: C₁₇H₂₀FN₃O₃·CH₄O₃S•2H₂O
• Purity: 95%
• Molecular weight: 465.49

Pefloxacin mesilate dihydrate CRS

CAS: 149676-40-4

• Formula: C₁₈H₂₈FN₃O₈S
• Molecular weight: 465.4936

Pefloxacin Mesylate Dihydrate

CAS: 149676-40-4

Pefloxacin Mesylate Dihydrate (1589 RB) , an antibacterial agent, restrains bacterial DNA replication by inhibiting …

• Formula: C₁₇H₂₀FN₃O₃·CH₄O₃S·2H₂O
• Purity: 99.79%
• Color and Shape: Solid
• Molecular weight: 465.49

1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID

CAS: 149676-40-4

• Formula: C₁₈H₂₈FN₃O₈S
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 465.4936

1-Ethyl-6-Fluoro-7-(4-Methylpiperazin-1-YL)-4-Oxo-Quinoline-3-Carboxylic Acid

CAS: 149676-40-4

• Purity: 99.5%
• Molecular weight: 465.49g/mol

Pefloxacin mesylate dihydrate

CAS: 149676-40-4

• Formula: C₁₇H₂₀FN₃O₃·CH₄O₃S· 2H₂O
• Purity: ≥ 98.0% (anhydrous)
• Color and Shape: White or almost white powder
• Molecular weight: 465.50

PharmaVetResiMix 3 Quinolones-v18 10 µg/mL in Methanol

CAS: 115550-35-1 119478-55-6 14698-29-4 149676-40-419562-30-2 28657-80-9 389-08-2 42835-25-6 51940-44-4 70458-96-7 74011-58-8 79660-72-3 82419-36-1 85721-33-1 91296-86-5 91296-87-6 93106-60-6 98079-52-8

• Color and Shape: Mixture

Smart Solutions™ v59 PharmaVetResiMix Kit 1

CAS: 100-90-3 113507-06-5 115550-35-1 117704-25-3 119478-55-6 122-11-2 1220-83-3 123997-26-2 127-71-9 127-79-7 144-82-1 144-83-2 14698-29-4 148-79-8 149676-40-4155569-91-8 19562-30-2 20559-55-1 2447-57-6 28657-80-9 31430-15-6 31431-39-7 389-08-2 42835-25-6 43210-67-9 515-64-0 51940-44-4 53716-50-0 54029-12-8 54965-21-8 57-67-0 57-68-1 58306-30-2 59-40-5 63-74-1 651-06-9 68-35-9 68786-66-3 70288-86-7 70458-96-7 71751-41-2 72-14-0 723-46-6 729-99-7 74011-58-8 75184-71-3 79660-72-3 80-08-0 80-32-0 80-35-3 80983-34-2 82419-36-1 85721-33-1 88254-99-3 91296-86-5 91296-87-6 93106-60-6 948-71-0 98079-52-8

• Color and Shape: Mixture

Pefloxacin Mesilate Dihydrate

CAS: 149676-40-4

• Formula: C₁₇H₂₀FN₃O₃·CH₄O₃SH₂O
• Color and Shape: Neat
• Molecular weight: 465.49

Pefloxacine Mesylate Dihydrate

CAS: 149676-40-4

• Formula: C₁₇H₂₀FN₃O₃·CH₄O₃S·2H₂O
• Purity: >95.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 465.49

Pefloxacin Mesylate Dihydrate

CAS: 149676-40-4

Applications Pefloxacin Mesylate Dihydrate is an analog of norfloxacin that inhibits topoisomerase.

• Formula: C₁₇H₂₀FN₃O₃·CH₄O₃SH₂O
• Color and Shape: Light Yellow
• Molecular weight: 465.49

Pefloxacin mesylate dihydrate

CAS: 149676-40-4

Pefloxacin mesylate is a prodrug of pefloxacin that is hydrolyzed to the active form in …

• Formula: C₁₇H₂₀FN₃O₃·CH₄O₃S·2H₂O
• Purity: Min. 95%
• Molecular weight: 465.49 g/mol