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CAS 91296-87-6

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Sarafloxacin hydrochloride

Description:
Sarafloxacin hydrochloride is a synthetic fluoroquinolone antibiotic primarily used in veterinary medicine, particularly for treating bacterial infections in livestock and poultry. It exhibits broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes for DNA replication and transcription. The compound is typically presented as a white to off-white crystalline powder, soluble in water and methanol, which facilitates its administration in aqueous formulations. Sarafloxacin hydrochloride has a relatively low toxicity profile, but like other fluoroquinolones, it may cause side effects such as gastrointestinal disturbances or potential effects on cartilage development in young animals. Its use is regulated in many countries due to concerns about antibiotic resistance and the potential for residues in food products. As with any antibiotic, it is crucial to use Sarafloxacin hydrochloride judiciously to minimize the risk of resistance development and ensure the efficacy of this important therapeutic agent.
Formula:C20H17F2N3O3·ClH
InChI:InChI=1S/C20H17F2N3O3.ClH/c21-12-1-3-13(4-2-12)25-11-15(20(27)28)19(26)14-9-16(22)18(10-17(14)25)24-7-5-23-6-8-24;/h1-4,9-11,23H,5-8H2,(H,27,28);1H
InChI key:InChIKey=KNWODGJQLCISLC-UHFFFAOYSA-N
SMILES:O=C1C=2C(N(C=C1C(O)=O)C3=CC=C(F)C=C3)=CC(=C(F)C2)N4CCNCC4.Cl
Synonyms:
  • 3-Quinolinecarboxylic acid, 6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, hydrochloride (1:1)
  • 3-Quinolinecarboxylic acid, 6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, monohydrochloride
  • 6-Fluoro-1-(4-Fluorophenyl)-4-Oxo-7-(Piperazin-1-Yl)-1,4-Dihydroquinoline-3-Carboxylic Acid Hydrochloride (1:1)
  • 6-Fluoro-1-(4-fluorophenyl)-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid hydrochloride
  • Sarafin
  • Sarafloxacin hcl
  • Sarafloxacin hydrochloride
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