CAS 158063-66-2
:4-(trifluoromethyl)nicotinic acid
Description:
4-(Trifluoromethyl)nicotinic acid, with the CAS number 158063-66-2, is a derivative of nicotinic acid featuring a trifluoromethyl group at the para position of the pyridine ring. This compound is characterized by its polar nature due to the presence of both the carboxylic acid functional group and the electronegative trifluoromethyl group, which can influence its solubility and reactivity. It typically appears as a white to off-white solid and is soluble in polar solvents. The trifluoromethyl group enhances the compound's lipophilicity and can affect its biological activity, making it of interest in medicinal chemistry and agrochemical applications. Additionally, the presence of the pyridine ring contributes to its aromatic properties and potential interactions in various chemical environments. Overall, 4-(trifluoromethyl)nicotinic acid is a valuable compound in research, particularly in the development of pharmaceuticals and other functional materials.
Formula:C7H3Cl2F3N2O
InChI:InChI=1/C7H3Cl2F3N2O/c8-3-1-2(7(10,11)12)4(6(13)15)5(9)14-3/h1H,(H2,13,15)
SMILES:c1c(c(c(Cl)nc1Cl)C(=N)O)C(F)(F)F
Synonyms:- 4-(Trifluoromethyl)pyridine-3-carboxylic acid
- 2,6-Dichloro-4-(Trifluoromethyl)Pyridine-3-Carboxamide
- 4-(Trifluoromethyl)-3-pyridinecarboxylic acid
- 4-Trifluoromethylnicotinic acid
- 4-(Trifluoro Methyl)Nicotinic Acid
- 4-(Trifluoro Methyl)Pyridine-3-Carboxylic Acid
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Found 11 products.
4-(Trifluoromethyl)nicotinic acid, 98%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci
Formula:C7H4F3NO2Purity:98%Color and Shape:White to orange, Crystals or powder or crystalline powder or fused solidMolecular weight:191.113-Pyridinecarboxylic acid, 4-(trifluoromethyl)-
CAS:Formula:C7H4F3NO2Purity:97%Color and Shape:SolidMolecular weight:191.1074Ref: IN-DA001PXU
1g20.00€5g24.00€10g31.00€1kg240.00€25g40.00€50g52.00€5kgTo inquire100g73.00€250g113.00€25kgTo inquire500g182.00€100kgTo inquire4-(Trifluoromethyl)nicotinic acid
CAS:4-(Trifluoromethyl)nicotinic acid
Formula:C7H4F3NO2Purity:97%Color and Shape: light brown powderMolecular weight:191.11g/mol4-(Trifluoromethyl)nicotinic acid
CAS:Compound FL0181, with CAS No. 158063-66-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound FL0181 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C7H4F3NO2Purity:98%Molecular weight:191.114-(Trifluoromethyl)nicotinic Acid
CAS:Formula:C7H4F3NO2Purity:>98.0%(GC)(T)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:191.11Flonicamid (free acid) 100 µg/mL in Acetonitrile
CAS:Formula:C7H4F3NO2Color and Shape:Single SolutionMolecular weight:191.11Flonicamid (free acid)
CAS:Controlled ProductFormula:C7H4F3NO2Color and Shape:NeatMolecular weight:191.114-(Trifluoromethyl)-3-Pyridinecarboxylic Acid
CAS:Controlled ProductApplications 4-(Trifluoromethyl)-3-Pyridinecarboxylic Acid is a useful synthetic intermediate. It can be used to prepare pyridine carboxamides as palm site inhibitors of HCV NS5B polymerase. It can also be used to synthesize pyrazolylcarboxanilides as Ca2+ release-activated Ca2+ (CRAC) channel inhibitors.
References Cheng, C., et al.: ACS Med. Chem. Lett., 1, 466 (2010); Yonetoku, Y., et al.: Bioorg. Med. Chem., 16, 9457 (2008)Formula:C7H4F3NO2Color and Shape:YellowMolecular weight:191.114-(Trifluoromethyl)nicotinic acid
CAS:Formula:C7H4F3NO2Purity:97%Color and Shape:SolidMolecular weight:191.109
