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CAS 163217-43-4

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Fmoc-p-azido-Phe-OH

Description:
Fmoc-p-azido-Phe-OH, with the CAS number 163217-43-4, is a chemical compound commonly used in peptide synthesis and bioconjugation applications. It features a phenylalanine (Phe) residue modified with an azido group, which is a functional group containing three nitrogen atoms (N3) that is highly reactive and useful for click chemistry. The Fmoc (9-fluorenylmethoxycarbonyl) group serves as a protecting group for the amino functionality, allowing for selective reactions during peptide synthesis. This compound is typically solid at room temperature and is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane. Its azido group enables the formation of stable linkages with various biomolecules, making it valuable in the development of targeted therapeutics and in the study of protein interactions. Safety precautions should be observed when handling this compound, as azides can be hazardous under certain conditions. Overall, Fmoc-p-azido-Phe-OH is a versatile building block in the field of organic and medicinal chemistry.
Formula:C24H20N4O4
Synonyms:
  • Fmoc-Phe(4-N)-OH
  • Fmoc-p-azido-L-phenylalanine
  • Fmoc-L-4-azidophenylalanine
  • Fmoc-Phe(4-N3)-OH
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