CAS 170713-75-4

nociceptin

Description:

Nociceptin, also known as nociceptin/orphanin FQ, is a neuropeptide that plays a significant role in pain modulation, stress response, and various physiological processes. It is derived from the precursor protein prepronociceptin and is characterized by its unique amino acid sequence. Nociceptin binds to the nociceptin receptor (NOP), which is part of the opioid receptor family, but it does not exhibit the typical analgesic effects associated with classical opioids. Instead, nociceptin is involved in the regulation of pain perception, emotional responses, and neuroendocrine functions. Its actions can be complex, as it may have both pro-nociceptive and anti-nociceptive effects depending on the context and the specific neural pathways involved. Additionally, nociceptin has been implicated in various conditions, including anxiety, depression, and addiction, making it a target of interest for therapeutic research. The CAS number 170713-75-4 specifically identifies this peptide, facilitating its recognition in scientific literature and databases.

Formula: C₇₉H₁₂₉N₂₇O₂₂

Synonyms:

• Orphanin Fq
• H-Phe-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-Arg-Lys-Leu-Ala-Asn-Gln-OH

Nociceptin

CAS: 170713-75-4

Nociceptin is an endogenous agonist of the opioid receptor-like ORL1 receptor.

Formula: C₇₉H₁₂₉N₂₇O₂₂

Color and Shape: White Powder

Molecular weight: 1809.06

Ref: 01-4031112

Nociceptin

CAS: 170713-75-4

Nociceptin (Orphanin FQ) is a 17-amino-acid polypeptide that is structurally related to the opioid peptide dynorphin A.

Formula: C₇₉H₁₂₉N₂₇O₂₂

Purity: 99.35%

Color and Shape: Solid

Molecular weight: 1809.04

Ref: TM-TP1071

Nociceptin (Human)

CAS: 170713-75-4

Nociceptin is a peptide that binds to the NOP receptor and activates it, which inhibits neuronal activity. It has been shown to inhibit protein interactions by acting as an inhibitor of the enzyme proteasome. Nociceptin activates the Ligand-gated ion channels, which are involved in pain perception. Nociceptin also has been used as a research tool for investigating protein interactions and antibody production.

Formula: C₇₉H₁₂₉N₂₇O₂₂

Purity: Min. 95%

Molecular weight: 1,809 g/mol

Ref: 3D-PNO-4318-V

Nociceptin trifluoroacetate salt

CAS: 170713-75-4

Nociceptin trifluoroacetate salt is an opioid with low potency that is used in the treatment of pain. It has been shown to bind to the protein and inhibit protease, which has been proposed as a possible mechanism for its analgesic effects. Nociceptin trifluoroacetate salt may also have indirect effects on brain functions by regulating levels of nociceptin, a neuropeptide that interacts with nociceptive neurons in the brain. This drug has been shown to have nootropic effects in mice, including increased locomotor activity and improved memory retention. Nociceptin trifluoroacetate salt inhibits kappa-opioid receptors and is therefore used as a pharmacological tool for research into opioid receptor function.

Formula: C₇₉H₁₂₉N₂₇O₂₂

Purity: Min. 95%

Molecular weight: 1,809.04 g/mol

Ref: 3D-FN108853