Description:Nociceptin, also known as nociceptin/orphanin FQ, is a neuropeptide that plays a significant role in pain modulation, stress response, and various physiological processes. It is derived from the precursor protein prepronociceptin and is characterized by its unique amino acid sequence. Nociceptin binds to the nociceptin receptor (NOP), which is part of the opioid receptor family, but it does not exhibit the typical analgesic effects associated with classical opioids. Instead, nociceptin is involved in the regulation of pain perception, emotional responses, and neuroendocrine functions. Its actions can be complex, as it may have both pro-nociceptive and anti-nociceptive effects depending on the context and the specific neural pathways involved. Additionally, nociceptin has been implicated in various conditions, including anxiety, depression, and addiction, making it a target of interest for therapeutic research. The CAS number 170713-75-4 specifically identifies this peptide, facilitating its recognition in scientific literature and databases.
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