CAS 17321-77-6
:clomipramine hydrochloride
Description:
Clomipramine hydrochloride is a tricyclic antidepressant primarily used in the treatment of obsessive-compulsive disorder (OCD) and other mood disorders. It functions by inhibiting the reuptake of neurotransmitters, particularly serotonin and norepinephrine, thereby enhancing their availability in the synaptic cleft. This compound appears as a white to off-white crystalline powder and is soluble in water, making it suitable for oral administration. Clomipramine hydrochloride has a relatively long half-life, which allows for once-daily dosing in many cases. Its pharmacological profile includes a range of side effects, such as sedation, dry mouth, and potential cardiovascular effects, necessitating careful monitoring in patients. The substance is classified as a prescription medication and is subject to regulatory controls due to its potential for side effects and interactions with other drugs. Overall, clomipramine hydrochloride is an important therapeutic agent in psychiatry, particularly for patients with treatment-resistant OCD.
Formula:C19H24Cl2N2
InChI:InChI=1/C19H23ClN2.ClH/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22;/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3;1H
InChI key:InChIKey=WIMWMKZEIBHDTH-UHFFFAOYSA-N
SMILES:C(CCN(C)C)N1C=2C(CCC=3C1=CC=CC3)=CC=C(Cl)C2.Cl
Synonyms:- 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride (1:1)
- 3-Chloro-5-(3-dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride
- 3-Chloroimipramine hydrochloride
- 5H-Dibenz[b,f]azepine, 3-chloro-5-[3-(dimethylamino)propyl]-10,11-dihydro-, monohydrochloride
- 5H-Dibenz[b,f]azepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-, hydrochloride (1:1)
- 5H-Dibenz[b,f]azepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-, monohydrochloride
- Anafranil
- Anaphranil
- Anatranil
- Chlorimipramine hydrochloride
- Chloroimipram-ine HCl
- Chloroimipramine monohydrochloride
- Clomipramine HCl
- ANAFRANIL HYDROCHLORIDE
- 5H-Dibenzb,fazepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-, monohydrochloride
- CLOMIPRAMINE HYDROCHLORIDE
- Clomipraminhydrochlorid
- 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride
- Chlomipramine
- 3-chloro-5-[3-(dimethylamino)propyl]-10,11-dihydro-5h-dibenz[b,f]azepine monohydrochloride
- 3-chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-5h-dibenz(b,f)azepinemono
- 3-CHLORO-10,11-DIHYDRO-N,N-DIMETHYL-5H-DIBENZ[B,F]AZEPINE-5-PROPANAMINE HYDROCHLORIDE
- f)azepine,10,11-dihydro-3-chloro-5-(3-(dimethylamino)propyl)-5h-dibenz(mon
- f)azepine-5-propanamine,3-chloro-10,11-dihydro-n,n-dimethyl-5h-dibenz(mo
- CLOMIPRAMINE HYDROCHLORIDE \ SEROTONIN U PTAKE INHIBITOR, ANTIDEPRESSANT
- 3-chloroimipraminehydrochloride
- CHLOROIMIPRAMINE HYDROCHLORIDE
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Clomipramine hydrochloride
CAS:<p>Potent, selective 5-HT uptake blocker</p>Formula:C19H24Cl2N2Color and Shape:White to pale yellow, Crystals or crystalline powderMolecular weight:351.32Clomipramine hydrochloride
CAS:Clomipramine hydrochlorideFormula:C19H23ClN2HClPurity:99.6%Color and Shape:White To Off-WhiteMolecular weight:350.13165Clomipramine Hydrochloride
CAS:Antidepressants, tranquilizers and other psychotherapeuFormula:C19H23ClN2·ClHColor and Shape:White Yellow PowderMolecular weight:350.13165(3-{5-chloro-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl}propyl)dimethylamine hydrochloride
CAS:Formula:C19H24Cl2N2Purity:99%Color and Shape:SolidMolecular weight:351.3133Clomipramine hydrochloride
CAS:Clomipramine HCl (Anafranil) is a serotonin-inhibiting tricyclic antidepressant, well-absorbed and metabolized to desmethylclomipramine in the liver.Formula:C19H23ClN2·HClPurity:99.04% - 99.47%Color and Shape:White To Slightly Yellow Crystalline PowderMolecular weight:351.31Clomipramine-13C-d3 HCl
CAS:Formula:C1813CH20D3ClN2·HClColor and Shape:White To Off-White SolidMolecular weight:318.87 36.46Clomipramine HCl
CAS:Formula:C19H23ClN2·HClColor and Shape:Off-White SolidMolecular weight:314.86 36.46Clomipramine Hydrochloride
CAS:Controlled ProductFormula:C19H23ClN2·ClHColor and Shape:NeatMolecular weight:351.31Clomipramine Hydrochloride (Standard)
CAS:Clomipramine Hydrochloride (Standard) is the standard substance of Clomipramine Hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Clomipramine hydrochloride (Anafranil) is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.Formula:C19H23ClN2·HClMolecular weight:351.31Clomipramine Hydrochloride
CAS:Formula:C19H23ClN2·HClPurity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:351.32Clomipramine hydrochloride
CAS:Formula:C19H23ClN2·HClPurity:98.0 - 102.0 % (dried basis)Color and Shape:White or almost white crystalline powderMolecular weight:351.32Clomipramine Hydrochloride
CAS:Controlled Product<p>Applications Serotonin reuptake inhibitor. Antidepressant; antiobsessional agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Peters, M.D., et al.: Clin. Pharm., 9, 165 (1990), Adamczyk, M., et al.: Ther. Drug Monit., 17, 371 (1995), Poolsup, N., et al.: J. Clin. Pharm. Ther., 25, 197 (2000), Bose, D., et al.: J. Pharmacol. Toxicol. Methods, 52, 323 (2005),<br></p>Formula:C19H23ClN2·ClHColor and Shape:White To Off-WhiteMolecular weight:351.31














