CAS 17321-77-6: clomipramine hydrochloride
Description:Clomipramine hydrochloride is a tricyclic antidepressant primarily used in the treatment of obsessive-compulsive disorder (OCD) and other mood disorders. It functions by inhibiting the reuptake of neurotransmitters, particularly serotonin and norepinephrine, thereby enhancing their availability in the synaptic cleft. This compound appears as a white to off-white crystalline powder and is soluble in water, making it suitable for oral administration. Clomipramine hydrochloride has a relatively long half-life, which allows for once-daily dosing in many cases. Its pharmacological profile includes a range of side effects, such as sedation, dry mouth, and potential cardiovascular effects, necessitating careful monitoring in patients. The substance is classified as a prescription medication and is subject to regulatory controls due to its potential for side effects and interactions with other drugs. Overall, clomipramine hydrochloride is an important therapeutic agent in psychiatry, particularly for patients with treatment-resistant OCD.
Formula:C19H23ClN2·ClH
InChI:InChI=1S/C19H23ClN2.ClH/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22;/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3;1H
InChI key:InChIKey=WIMWMKZEIBHDTH-UHFFFAOYSA-N
SMILES:Cl.ClC1=CC=C2C(=C1)N(C=3C=CC=CC3CC2)CCCN(C)C
- Synonyms:
- 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride (1:1)
- 3-Chloro-5-(3-dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride
- 3-Chloroimipramine hydrochloride
- 5H-Dibenz[b,f]azepine, 3-chloro-5-[3-(dimethylamino)propyl]-10,11-dihydro-, monohydrochloride
- 5H-Dibenz[b,f]azepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-, hydrochloride (1:1)
- 5H-Dibenz[b,f]azepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-, monohydrochloride
- Anafranil
- Anaphranil
- Anatranil
- Chlorimipramine hydrochloride
- See more synonyms
- Chloroimipram-ine HCl
- Chloroimipramine monohydrochloride
- Clomipramine HCl