CAS: 192185-72-1 - Tipifarnib

Formula: C₂₇H₂₂Cl₂N₄O

InChI: InChI=1S/C27H22Cl2N4O/c1-32-16-31-15-25(32)27(30,18-6-9-20(28)10-7-18)19-8-11-24-23(13-19)22(14-26(34)33(24)2)17-4-3-5-21(29)12-17/h3-16H,30H2,1-2H3/t27-/m1/s1

InChI key: InChIKey=PLHJCIYEEKOWNM-HHHXNRCGSA-N

SMILES: O=C1C=C(C=2C=CC=C(Cl)C2)C=3C=C(C=CC3N1C)C(N)(C4=CC=C(Cl)C=C4)C5=CN=CN5C

Synonyms:

• (R)-(+)-R 115777
• (R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone
• 2(1H)-Quinolinone, 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-
• 6-[(R)-Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone
• 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one
• Tipifarnib Zarnestra
• Zarnestra

2(1H)-Quinolinone, 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-

CAS: 192185-72-1

• Formula: C₂₇H₂₂Cl₂N₄O
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 489.3958

Tipifarnib

CAS: 192185-72-1

Tipifarnib

CAS: 192185-72-1

Tipifarnib (IND 58359) is a nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib binds to and …

• Formula: C₂₇H₂₂Cl₂N₄O
• Purity: 99.22%
• Color and Shape: Off-White To Pale Beige Solid
• Molecular weight: 489.4

Tipifarnib

CAS: 192185-72-1

• Formula: H₂
• Purity: >98%
• Color and Shape: white solid
• Molecular weight: 489.40g/mol

Tipifarnib

CAS: 192185-72-1

Applications A farnesyltransferase inhibitor. Sensitizes human multiple myeloma cell to proteasome inhibition by blocking degradation …

• Formula: C₂₇H₂₂Cl₂N₄O
• Color and Shape: Off-White to Pale Beige Solid
• Molecular weight: 489.40

Tipifarnib

CAS: 192185-72-1

Tipifarnib is a peptide substrate that inhibits the enzyme DNA methyltransferase, which is responsible for …

• Formula: C₂₇H₂₂Cl₂N₄O
• Purity: Min. 95%
• Molecular weight: 489.4 g/mol