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Tipifarnib
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Tipifarnib

CAS: 192185-72-1

Ref. TM-T6271

1mg
40.00 €
2mg
52.00 €
5mg
83.00 €
10mg
128.00 €
25mg
235.00 €
50mg
426.00 €
1ml*10 (DMSO)
91.00 €
Estimated delivery in United States, on Thursday 16 May 2024

Product Information

Name:
Tipifarnib
Synonyms:
  • R115777, Zarnestra, IND 58359
  • (R)-(+)-R 115777
  • (R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone
  • 2(1H)-Quinolinone, 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-
  • 6-[(R)-Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone
  • 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one
  • Tipifarnib Zarnestra
  • Zarnestra
Description:

Tipifarnib (IND 58359) is a nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib binds to and inhibits the enzyme farnesyl protein transferase, an enzyme involved in protein processing (farnesylation) for signal transduction. By inhibiting the farnesylation of proteins, this agent prevents the activation of Ras oncogenes, inhibits cell growth, induces apoptosis, and inhibits angiogenesis.

Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
489.4
Formula:
C27H22Cl2N4O
Purity:
99.22%
Color/Form:
Off-White To Pale Beige Solid
MDL:
Melting point:
Boiling point:
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Density:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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