CAS 1926986-36-8

Formula: C24H25N5O3

InChI: InChI=1S/C24H25N5O3/c1-3-4-7-29-14-19(17-5-6-25-22(17)24(29)31)18-12-16(13-20-21(18)26-15-27(20)2)23(30)28-8-10-32-11-9-28/h3,5-6,12-15,25H,1,4,7-11H2,2H3

InChI key: XJRUWGFZGQNPPD-UHFFFAOYSA-N

SMILES: CN1C=NC2=C(C=C(C=C21)C(=O)N3CCOCC3)C4=CN(C(=O)C5=C4C=CN5)CCC=C

GNE-371

CAS: 1926986-36-8

GNE-371

Formula: C₂₄H₂₅N₅O₃

Purity: ≥98%

Molecular weight: 431.49

Ref: 54-BUP21993

GNE-371

CAS: 1926986-36-8

Purity: 98.21%

Ref: IN-DA01K2IE

GNE 371

CAS: 1926986-36-8

A chemical probe for the dual bromodomains of human transcription-initiation-factor TFIID subunit 1 (TAF1). GNE 371 binds TAF1 with an IC50 of 10 nM and is selective over other bromodomain family members. Exerts anti-proliferative effects in synergy with BET inhibitor JQ1.

Formula: C₂₄H₂₅N₅O₃

Purity: (Hplc-Ms) Min. 98 Area-%

Molecular weight: 431.49 g/mol

Ref: 3D-BG167527

GNE-371

CAS: 1926986-36-8

GNE-371 is a probe for human transcription initiation factor TFIID subunit 1 and transcription initiation factor TFIID subunit 1-like second bromodomain.

Formula: C₂₄H₂₅N₅O₃

Purity: 98.21%

Color and Shape: Solid

Molecular weight: 431.487

Ref: TM-T15401