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GNE 371
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GNE 371

CAS: 1926986-36-8

Ref. 3D-BG167527

1mg
189.00 €
5mg
452.00 €
10mg
817.00 €
25mg
1,417.00 €
50mg
2,226.00 €
Estimated delivery in United States, on Monday 13 May 2024

Product Information

Name:
GNE 371
Description:

A chemical probe for the dual bromodomains of human transcription-initiation-factor TFIID subunit 1 (TAF1). GNE 371 binds TAF1 with an IC50 of 10 nM and is selective over other bromodomain family members. Exerts anti-proliferative effects in synergy with BET inhibitor JQ1.

Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
431.49 g/mol
Formula:
C24H25N5O3
Purity:
(Hplc-Ms) Min. 98 Area-%
InChI:
InChI=1S/C24H25N5O3/c1-3-4-7-29-14-19(17-5-6-25-22(17)24(29)31)18-12-16(13-20-21(18)26-15-27(20)2)23(30)28-8-10-32-11-9-28/h3,5-6,12-15,25H,1,4,7-11H2,2H3
InChI key:
InChIKey=XJRUWGFZGQNPPD-UHFFFAOYSA-N
SMILES:
C=CCCn1cc(-c2cc(C(=O)N3CCOCC3)cc3c2ncn3C)c2cc[nH]c2c1=O
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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