CAS 2022-85-7
:Flucytosine
Description:
Flucytosine, with the CAS number 2022-85-7, is an antifungal medication primarily used to treat serious fungal infections, particularly those caused by Candida and Cryptococcus species. It is a pyrimidine analog that interferes with nucleic acid synthesis by inhibiting thymidylate synthase, ultimately disrupting fungal DNA and RNA synthesis. Flucytosine is typically administered in conjunction with other antifungal agents, such as amphotericin B, to enhance its efficacy and reduce the risk of resistance. The substance is well-absorbed when taken orally and is distributed widely throughout the body, including the central nervous system, making it effective for treating cryptococcal meningitis. Flucytosine is generally well-tolerated, but it can cause side effects such as bone marrow suppression and gastrointestinal disturbances. Its use requires careful monitoring of renal function and blood counts due to potential toxicity. Overall, flucytosine is a valuable tool in the antifungal arsenal, particularly for immunocompromised patients.
Formula:C4H4FN3O
InChI:InChI=1/C4H4FN3O/c5-8-2-1-3(6)7-4(8)9/h1-2H,(H2,6,7,9)
InChI key:InChIKey=XRECTZIEBJDKEO-UHFFFAOYSA-N
SMILES:NC1=C(F)C=NC(=O)N1
Synonyms:- 2(1H)-Pyrimidinone, 4-amino-5-fluoro-
- 2(1H)-Pyrimidinone, 6-amino-5-fluoro-
- 2-Hydroxy-4-Amino-5-Fluoropyrimidine
- 4-Amino-5-Fluoro-2(1H)-Pyrimidinone
- 4-Amino-5-fluoro-2(1H)-pyrmidinone
- 4-Amino-5-fluoropyrimidin-2(1H)-one
- 4-Amino-5-fluoropyrimidin-2-ol
- 4-amino-1-fluoropyrimidin-2(1H)-one
- 5-Flucytosine
- 5-Fluoro Cytosine
- 5-Fluorocystosine
- 5-Fluorocytosin
- 5-Fluorocytosine
- 6-Amino-2-oxo-5-fluoropyrimidine
- 6-Amino-5-fluoro-2(1H)-pyrimidinone
- 6-amino-5-fluoropyrimidin-2(1H)-one
- Alcobon
- Ancobon
- Ancotil
- Ancotyl
- Cytosine, 5-fluoro-
- Flucitosina
- Flucylosine
- Flucytosin
- Flucytosine
- Fluocytosine
- Nsc 103805
- Ro 2-9915
- Toca FC
- 5-FC
- TIMTEC-BB SBB000061
- 4-AMINO-5-FLUORO-3H-PYRIMIDIN-2-ONE
- FLUCYSTINE
- fluorocytosine
- 4-amino-5-fluoro-2(1h)-pyrimidinon
- 4-AMINO-5-FLUORO-2(1H)-PYRIMIDINE
- See more synonyms
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5-Fluorocytosine
CAS:Formula:C4H4FN3OPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:129.095-Fluorocytosine, 98+%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo SciFormula:C4H4FN3OPurity:98+%Color and Shape:White, crystalline powderMolecular weight:129.09FLUCYTOSINE FOR SYSTEM SUITABILITY CRS
CAS:FLUCYTOSINE FOR SYSTEM SUITABILITY CRSFormula:C4H4FN3OMolecular weight:129.0925FLUCYTOSINE CRS
CAS:FLUCYTOSINE CRSFormula:C4H4FN3OColor and Shape:Crystalline Powder. White. Powder.Molecular weight:129.0925Flucytosine
CAS:Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structureFormula:C4H4FN3OColor and Shape:White Off-White Crystalline PowderMolecular weight:129.03384Flucytosine
CAS:Flucytosine (NSC 103805) is a pyrimidine compound and a fluorinated cytosine analog exhibiting antifungal activity.Formula:C4H4FN3OPurity:98.76% - 99.28%Color and Shape:White Crystalline Solid SolidMolecular weight:129.092(1H)-Pyrimidinone, 6-amino-5-fluoro-
CAS:Formula:C4H4FN3OPurity:95%Color and Shape:SolidMolecular weight:129.09255-Fluorocytosine
CAS:5-FluorocytosineFormula:C4H4FN3OPurity:97%Color and Shape: off white powderMolecular weight:129.09g/mol5-Fluorocytosine
CAS:Formula:C4H4FN3OPurity:≥ 98.0%Color and Shape:White to off-white crystalline powderMolecular weight:129.095-Fluoro Cytosine
CAS:Controlled ProductApplications 5-FC is a toxic antifungal/antimicrobial agent.
References Gopinath, P., et al.: Biotechnol. Lett., 30, 1913 (2008), Kalkanci, A., et al.: Microbiol Immunol., 52, 435 (2008), Dubeau, M., et al.: App. Env. Microbiol., 75, 1211 (2009),Formula:C4H4FN3OColor and Shape:White To Off-WhiteMolecular weight:129.09Cytosine-13C,15N2
CAS:Formula:CC3H515N2NOColor and Shape:Off-White To Light YellowMolecular weight:114.08
