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CAS 20559-55-1

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Oxibendazole

Description:
Oxibendazole is a benzimidazole derivative primarily used as an anthelmintic agent, effective against a variety of parasitic worms in veterinary medicine. It is characterized by its broad-spectrum activity, particularly against nematodes and some cestodes. The compound is typically presented as a white to off-white crystalline powder, which is relatively insoluble in water but soluble in organic solvents. Oxibendazole functions by inhibiting the polymerization of tubulin, disrupting microtubule formation, and ultimately leading to the paralysis and death of the parasites. Its pharmacokinetics involve absorption in the gastrointestinal tract, with a relatively long half-life, allowing for effective dosing regimens. Additionally, it has a favorable safety profile when used in recommended doses, making it a popular choice in livestock and companion animal treatments. As with any pharmaceutical, proper handling and adherence to dosage guidelines are essential to minimize potential side effects and resistance development in target parasites.
Formula:C15H13N3O3S
InChI:InChI=1/C12H15N3O3/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)
InChI key:InChIKey=RAOCRURYZCVHMG-UHFFFAOYSA-N
SMILES:N(C(OC)=O)C=1NC=2C(N1)=CC(OCCC)=CC2
Synonyms:
  • 2-Benzimidazolecarbamic acid, 5-propoxy-, methyl ester
  • 5-Propoxy-2-(carbomethoxyamino)benzimidazole
  • Anthelcide EQ
  • Carbamic acid, (5-propoxy-1H-benzimidazol-2-yl)-, methyl ester
  • Carbamic acid, N-(6-propoxy-1H-benzimidazol-2-yl)-, methyl ester
  • Loditac
  • Methyl (5-Propoxy-1H-Benzimidazol-2-Yl)Carbamate
  • Methyl (5-n-propoxy-2-benzimidazolyl)carbamate
  • Methyl 5-propoxybenzimidazole-2-carbamate
  • Oxibendazole
  • See more synonyms
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