CAS 2068-78-2: Vincristine sulfate

Description: Vincristine sulfate is a potent alkaloid derived from the periwinkle plant, Vinca rosea, and is primarily used in chemotherapy for treating various types of cancer, including leukemia and lymphoma. It functions as a vinca alkaloid, inhibiting microtubule formation during cell division, which effectively disrupts mitosis and halts cancer cell proliferation. The compound appears as a white to off-white powder and is soluble in water, making it suitable for intravenous administration. Vincristine sulfate has a molecular formula that reflects its complex structure, characterized by multiple ring systems and functional groups. Its pharmacokinetics involve hepatic metabolism, and it is known for its neurotoxic side effects, which can lead to peripheral neuropathy. Additionally, it has a narrow therapeutic index, necessitating careful dosing and monitoring. Due to its mechanism of action and side effect profile, vincristine sulfate is often part of combination chemotherapy regimens, enhancing the overall efficacy of cancer treatment while minimizing resistance development.

Formula: C₄₆H₅₆N₄O₁₀·H₂O₄S

InChI: InChI=1S/C46H56N4O10.H2O4S/c1-7-42(55)22-28-23-45(40(53)58-5,36-30(14-18-48(24-28)25-42)29-12-9-10-13-33(29)47-36)32-20-31-34(21-35(32)57-4)50(26-51)38-44(31)16-19-49-17-11-15-43(8-2,37(44)49)39(60-27(3)52)46(38,56)41(54)59-6;1-5(2,3)4/h9-13,15,20-21,26,28,37-39,47,55-56H,7-8,14,16-19,22-25H2,1-6H3;(H2,1,2,3,4)/t28-,37-,38+,39+,42-,43+,44+,45-,46-;/m0./s1

InChI key: InChIKey=AQTQHPDCURKLKT-PNYVAJAMSA-N

SMILES: O=CN1C2=CC(OC)=C(C=C2C34CCN5CC=CC(CC)(C(OC(=O)C)C(O)(C(=O)OC)C13)C54)C6(C(=O)OC)C=7NC=8C=CC=CC8C7CCN9CC(CC(O)(C9)CC)C6.O=S(=O)(O)O

Synonyms:

• (2Alpha,2'Beta,3Alpha,4Alpha,5Beta,19Beta)-22-Oxovincaleukoblastine
• (2Alpha,2'Beta,3Alpha,4Alpha,5Beta,19Beta)-22-Oxovincaleukoblastine Sulfate
• (2Alpha,2'Beta,3Alpha,4Alpha,5Beta,19Beta)-22-Oxovincaleukoblastine Sulfate (1:1)
• (2Alpha,3Alpha,4Alpha,5Beta,19Beta)-22-Oxovincaleukoblastine Sulfate
• 22-Oxovincaleukoblastine sulfate salt
• Kyocristine
• Leurocristine sulfate
• Leurocristine sulfate salt
• Leurocristine, sulfate (1:1) (salt)
• Lilly 37231
• Marqibo
• NSC 67574
• Novopharm
• Oncovin
• Onkovin
• VCR sulfate
• Vincaleukoblastine, 22-oxo-, sulfate (1:1)
• Vincaleukoblastine, 22-oxo-, sulfate (1:1) (salt)
• Vincasar PFS
• Vincristine Sulfate, Apocynaceae sp.
• Vincristine Sulphate
• Vincristine hydrogen sulfate
• Vincristine sulfate liposome injection
• Vincristine sulfate salt
• Vincrisul

Vincristine sulfate, 97+%

CAS: 2068-78-2

Vincristine sulfate, is used as an anticancer agent, microtubule disrupter, Induces apoptosis in human lymphoma …

• Formula: C₄₆H₅₈N₄O₁₄S
• Purity: 97+%
• Molecular weight: 923.04

Vincristine sulfate CRS

CAS: 2068-78-2

• Formula: C₄₆H₅₈N₄O₁₄S
• Color and Shape: Powder
• Molecular weight: 923.0361

Vincristine Sulfate

CAS: 2068-78-2

Vegetable alkaloids, natural or reproduced by synthesis, their salts and other derivatives, nesoi

• Formula: C₄₆H₅₆N₄O₁₀·H₂SO₄
• Color and Shape: White Off-White Light Yellow Crystalline Powder
• Molecular weight: 824.39964

Vincaleukoblastine, 22-oxo-, sulfate (1:1)

CAS: 2068-78-2

• Formula: C₄₆H₅₈N₄O₁₄S
• Purity: %
• Color and Shape: Solid
• Molecular weight: 923.0361

Vincristine sulfate

CAS: 2068-78-2

Vincristine sulfate is a natural alkaloid. Vincristine sulfate is used as a microtubule destabilizer for …

• Formula: C₄₆H₅₈N₄O₁₄S
• Purity: 98% - 99.87%
• Color and Shape: White Crystalline Powder
• Molecular weight: 923.04

Vincristine sulfate

CAS: 2068-78-2

• Purity: 99.87%
• Molecular weight: 923.04g/mol

Vincristine sulfate

CAS: 2068-78-2

• Formula: C₄₆H₅₈N₄O₁₄S
• Purity: ≥ 98.0%
• Color and Shape: White to light yellow powder
• Molecular weight: 923.04

Vincristine, sulphate salt

CAS: 2068-78-2

• Formula: C₄₆H₅₆N₄O₁₀·H₂SO₄
• Purity: 99.66% (lc-ms) (Typical Value in Batch COA)
• Color and Shape: white to off-white solid
• Molecular weight: 923.04g/mol

Vincristine Sulfate

CAS: 2068-78-2

• Formula: C₄₆H₅₈N₄O₁₄S
• Purity: 95%~99%
• Molecular weight: 923.044

Vincristine sulfate, 95%

CAS: 2068-78-2

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₄₆H₅₈N₄O₁₄S
• Purity: 95%
• Color and Shape: Crystalline powder, White to light yellow
• Molecular weight: 923.04

Vincristine Sulfate RS

CAS: 2068-78-2

• Color and Shape: White To Light Yellow-White Solid Powder

Vincristine Sulfate

CAS: 2068-78-2

• Formula: C₄₆H₅₆N₄O₁₀·H₂O₄S
• Color and Shape: Off White
• Molecular weight: 923.04

Vincristine Sulfate (1mg/mL in DMSO)

CAS: 2068-78-2

• Formula: C₄₆H₅₆N₄O₁₀·H₂O₄S
• Color and Shape: Colourless

Vincristine sulfate

CAS: 2068-78-2

Inhibits assembly of mitotic spindle; depolymerizes microtubules; anti-cancer

• Formula: C₄₆H₅₈N₄O₁₄S
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 923.04 g/mol

Vincristine-d6 xSulfate

CAS: 2068-78-2

• Formula: C₄₆H₅₀D₆N₄O₁₀H₂O₄S
• Color and Shape: Neat
• Molecular weight: 830.99

Vincristine Sulfate

CAS: 2068-78-2

• Formula: C₄₆H₅₆N₄O₁₀·H₂SO₄
• Purity: >95.0%(HPLC)
• Color and Shape: White to Light yellow powder to crystaline
• Molecular weight: 923.04

Vincristine-d9 Sulfate

CAS: 2068-78-2

Applications Vincristine-d9 Sulfate, is an Labeled analogue of Vincristine Sulfate (V314250), which is an antitumor …

• Formula: C₄₆D₉H₄₇N₄O₁₀·H₂SO₄
• Color and Shape: Neat
• Molecular weight: 932.092

Vincristine Sulfate (Assay) (DISCONTINUED)

CAS: 2068-78-2

Other alkaloids,natural or reproduced by synthesis, and their salts, ethers,esters&other derivatives, nesoi

• Formula: C₄₆H₅₆N₄O₁₀·H₂SO₄
• Color and Shape: Powder
• Molecular weight: 922.36702