CAS 206978-14-5

Formula: C21H22O5

InChI: InChI=1S/C21H22O5/c1-13(4-6-18-21(2,3)26-18)8-10-24-20-14-5-7-19(22)25-17(14)12-16-15(20)9-11-23-16/h5,7-9,11-12,18H,4,6,10H2,1-3H3/b13-8+

InChI key: OOKSPQLCQUBEKU-MDWZMJQESA-N

SMILES: C/C(=C\COC1=C2C=CC(=O)OC2=CC3=C1C=CO3)/CCC4C(O4)(C)C

6',7'-Epoxybergamottin

CAS: 206978-14-5

6',7'-Epoxybergamottin

Formula: C₂₁H₂₂O₅

Purity: HP≥90%

Molecular weight: 354.4

Ref: 54-OR1108124

6',7'-Epoxybergamottin

CAS: 206978-14-5

6'7'-Epoxybergamottin: Found in grapefruit; inhibits CYP3A4 (IC50: 0.30 ppm); presents in juice (0.1-7.4 μM); blocks talinolol transport; is insecticidal.

Formula: C₂₁H₂₂O₅

Color and Shape: Solid

Molecular weight: 354.4

Ref: TM-T37810

Epoxybergamottin

CAS: 206978-14-5

Lactone

Formula: C₂₁H₂₂O₅

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 354.4

Ref: 5G-80438

Epoxybergamottin

CAS: 206978-14-5

Epoxybergamottin is a furanocoumarin derivative, which is a natural bioactive compound. It is primarily sourced from citrus fruits, particularly grapefruit. The primary mode of action of epoxybergamottin is the inhibition of cytochrome P450 enzymes, specifically CYP3A4. This enzyme is a major player in the metabolism of many pharmaceuticals, and its inhibition can lead to increased bioavailability and prolonged effects of drugs metabolized by this pathway.

Formula: C₂₁H₂₂O₅

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 354.40 g/mol

Ref: 3D-FE137821