CAS 2086-83-1

Berberine

Description:

Berberine is a naturally occurring isoquinoline alkaloid found in several plants, including goldenseal, barberry, and tree turmeric. It is characterized by its bright yellow color and has a molecular formula of C20H18NO4. Berberine exhibits a range of biological activities, including antimicrobial, anti-inflammatory, and antidiabetic properties, making it of interest in both traditional medicine and modern pharmacology. It functions primarily by modulating various cellular pathways, including those involved in glucose metabolism and lipid regulation. Berberine is known to interact with multiple molecular targets, including enzymes and receptors, which contributes to its diverse therapeutic effects. Additionally, it has been studied for its potential role in cardiovascular health and cancer treatment. Due to its low solubility in water, berberine's bioavailability can be limited, prompting research into various formulations to enhance its absorption. Overall, berberine is a compound of significant interest in both natural product chemistry and medicinal research.

Formula: C₂₀H₁₈NO₄

InChI: InChI=1S/C20H18NO4/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2/h3-4,7-10H,5-6,11H2,1-2H3/q+1

InChI key: InChIKey=YBHILYKTIRIUTE-UHFFFAOYSA-N

SMILES: O(C)C1=C2C=[N+]3C(C=4C(=CC5=C(C4)OCO5)CC3)=CC2=CC=C1OC

Synonyms:

• 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium
• 9,10-Dimethoxy-5,6-Dihydro[1,3]Dioxolo[4,5-G]Isoquino[3,2-A]Isoquinolin-7-Ium
• Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-
• Berbericine
• Berberin
• Berberina
• Berberone
• Berbinium, 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-
• Majarine
• Thalsine
• Umbellatin
• Umbellatine

Berberine Chloride Hydrate

CAS: 141433-60-5, 2086-83-1, 633-65-8

Formula: C₂₀H₁₈ClNO₄·xH₂O

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Yellow to Orange powder to crystaline

Molecular weight: 371.82 (as Anhydrous)

Ref: 3B-B0450

Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-

CAS: 2086-83-1

Formula: C₂₀H₁₈NO₄

Purity: 99%

Color and Shape: Solid

Molecular weight: 336.3612

Ref: IN-DA002JSP

Berberine

CAS: 2086-83-1

Berberine

Purity: 99%

Molecular weight: 336.36g/mol

Ref: 54-OR1029863

Berberine

CAS: 2086-83-1

Berberine

Purity: ≥95%

Molecular weight: 336.36g/mol

Ref: 54-BUP00092

Berberine

CAS: 2086-83-1

Berberine, a naturally occurring isoquinoline alkaloid, has been shown to possess anti-inflammatory and antitumor properties in some in vitro systems; berberine-induced apoptosis of human prostate cancer cells is mediated primarily through the caspase-dependent pathway, the effectiveness of berberine in checking the growth of androgen-insensitive, as well as androgen-sensitive, prostate cancer cells without affecting the growth of normal prostate epithelial cells indicates that it may be a promising candidate for prostate cancer therapy.

Formula: C₂₀H₁₈NO₄

Purity: 95%~99%

Color and Shape: Yellow powder

Molecular weight: 336.366

Ref: BP-BP0251

Berberine

CAS: 2086-83-1

1.

Formula: C₂₀H₁₈NO₄

Purity: 95.71% - 99.67%

Color and Shape: Solid

Molecular weight: 336.36

Ref: TM-T4S0797