CAS 2095849-04-8

Formula: C25H20F3N5O2

InChI: InChI=1S/C25H20F3N5O2/c1-15-6-7-21(31-23(34)16-4-3-5-20(9-16)25(26,27)28)10-22(15)32-24(35)18-8-17(11-29-12-18)19-13-30-33(2)14-19/h3-14H,1-2H3,(H,31,34)(H,32,35)

InChI key: BMEXIUCHJUGPRB-UHFFFAOYSA-N

SMILES: CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)NC(=O)C3=CN=CC(=C3)C4=CN(N=C4)C

CSF1R-IN-1

CAS: 2095849-04-8

CSF1R-IN-1 is a CSF1R inhibitor with IC50 of 0.5 nM.

Formula: C₂₅H₂₀F₃N₅O₂

Purity: 97.02% - 98.17%

Color and Shape: Solid

Molecular weight: 479.4538

Ref: TM-T10894

CSF1R-IN-1

CAS: 2095849-04-8

CSF1R-IN-1

Formula: C₂₅H₂₀F₃N₅O₂

Purity: ≥95%

Molecular weight: 479.45

Ref: 54-BUP07026

5-(1-Methyl-1H-pyrazol-4-yl)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)nicotinamide

CAS: 2095849-04-8

5-(1-Methyl-1H-pyrazol-4-yl)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)nicotinamide

Formula: C₂₅H₂₀F₃N₅O₂

Purity: 99%

Molecular weight: 479.45

Ref: 54-PC108760

5-(1-Methyl-1H-pyrazol-4-yl)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)nicotinamide

CAS: 2095849-04-8

Formula: C₂₅H₂₀F₃N₅O₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 479.4538

Ref: IN-DA01N148

CSF1R-IN-1

CAS: 2095849-04-8

5-(1-Methyl-1H-pyrazol-4-yl)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)nicotinamide

Formula: C₂₅H₂₀F₃N₅O₂

Purity: 99%

Molecular weight: 479.45

Ref: IN-DG01130506

CSF1R-IN-1

CAS: 2095849-04-8

CSF1R-IN-1 is a small molecule inhibitor, which is derived from synthetic chemical processes designed to selectively target the colony-stimulating factor 1 receptor (CSF1R) tyrosine kinase. The primary mode of action of CSF1R-IN-1 involves the inhibition of the CSF1R signaling pathway. This pathway is crucial for the regulation of the development and function of macrophages, which are vital for immune response and homeostasis. By selectively binding to the ATP-binding site of CSF1R, CSF1R-IN-1 effectively blocks the receptor's activity, thus reducing unwanted macrophage-mediated inflammation and proliferation.

Formula: C₂₅H₂₀F₃N₅O₂

Purity: Min. 95%

Molecular weight: 479.5 g/mol

Ref: 3D-VID84904