CAS 2105-43-3

Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-buten-1-yl]-, hydrochloride (1:1)

Description:

Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-buten-1-yl]-, hydrochloride (1:1), with CAS number 2105-43-3, is a complex organic compound characterized by its unique structural features, which include a pyrimidine ring and a dithioether moiety. This compound is typically encountered as a hydrochloride salt, enhancing its solubility in water and making it suitable for various biological applications. It exhibits properties such as moderate to high polarity due to the presence of functional groups like amines and hydroxyls, which can engage in hydrogen bonding. The presence of the tetrahydro-2-furanyl group suggests potential reactivity and stability under certain conditions. This compound may be of interest in pharmaceutical research, particularly in the development of therapeutic agents, due to its structural complexity and potential biological activity. However, specific safety and handling guidelines should be followed, as with all chemical substances, to mitigate any risks associated with its use.

Formula: C₁₇H₂₆N₄O₃S₂·ClH

InChI: InChI=1S/C17H26N4O3S2.ClH/c1-12(16(5-6-22)26-25-10-15-4-3-7-24-15)21(11-23)9-14-8-19-13(2)20-17(14)18;/h8,11,15,22H,3-7,9-10H2,1-2H3,(H2,18,19,20);1H

InChI key: InChIKey=OPGOLNDOMSBSCW-UHFFFAOYSA-N

SMILES: C(N(C(=C(SSCC1CCCO1)CCO)C)C=O)C=2C(N)=NC(C)=NC2.Cl

Synonyms:

• Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]-1-butenyl]-, monohydrochloride
• Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-buten-1-yl]-, hydrochloride (1:1)
• Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-butenyl]-, monohydrochloride
• Fursultiamine HCL
• Fursultiamine Hydrochloride
• N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-{(1E)-4-hydroxy-1-methyl-2-[(tetrahydrofuran-2-ylmethyl)disulfanyl]but-1-en-1-yl}formamide hydrochloride
• N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-{(1E)-4-hydroxy-2-[(tetrahydrofuran-2-ylmethyl)disulfanyl]but-1-en-1-yl}formamide hydrochloride
• TTFD hydrochloride
• Thiamin tetrahydrofurfuryl disulfide hydrochloride
• Thiamine tetrahydrofurfuryl disulfide hydrochloride
• N-((4-Amino-2-methylpyrimidin-5-yl)methyl)-N-(4-hydroxy-1-methyl-2-((tetrahydrofurfuryl)dithio)but-1-en-1-yl)formamide monohydrochloride

Fursultiamine Hydrochloride RS

CAS: 2105-43-3

Color and Shape: White

Ref: 2K-113500002

Fursultiamine Hydrochloride

Controlled Product

CAS: 2105-43-3

Applications Fursultiamine was synthesized for the purpose of developing forms of thiamine with improved lipophilicity for treating vitamin B1 deficiency. In addition to its clinical indication of avitaminosis, fursultiamine has been studied in clinical trials for Alzheimer's disease and autistic spectrum disorders with positive but modest benefits. It has also been investigated in improving energy metabolism during exercise and reducing exercise-induced fatigue with conflicting results.
References Miura, S.: Nippon Ganka Gakkai Zasshi, 69, 792 (1965); Mimori, Y., et al.: Met. Brain Disease, 11, 89 (1996); Webster, M., et al.: Eur. J. Appl. Physiol. Occup. Physio., 75, 520 (1997)

Formula: C₁₇H₂₇ClN₄O₃S₂

Color and Shape: Neat

Molecular weight: 435.00

Ref: TR-F865230

Fursultiamine Hydrochloride RS

CAS: 2105-43-3

Color and Shape: White

Ref: 2K-1135000021