CAS 213476-12-1

Lansoprazole N-Oxide

Description:

Lansoprazole N-Oxide is a chemical compound derived from lansoprazole, a proton pump inhibitor commonly used to treat conditions like gastroesophageal reflux disease (GERD) and peptic ulcers. The N-oxide form indicates that it has undergone oxidation, which can affect its pharmacological properties. This compound typically exhibits characteristics such as being a white to off-white solid, with a specific molecular structure that includes a pyridine ring and a benzimidazole moiety. Its solubility is generally in organic solvents, and it may have limited solubility in water. The N-oxide modification can influence the compound's stability, bioavailability, and metabolic pathways. In terms of safety, like many pharmaceuticals, it should be handled with care, and its effects on human health and the environment should be considered. As with any chemical substance, proper characterization through techniques such as NMR, mass spectrometry, and chromatography is essential for understanding its properties and potential applications in medicinal chemistry.

Lansoprazole impurity standard

CAS: 103577-45-3, 131926-99-3, 213476-12-1

Lansoprazole impurity standard

Color and Shape: White To Beige

Ref: 47-873

Lansoprazole N-Oxide ([[(1H-Benzimidazole-2-yl)sulfinyl]methyl]-3-methyl-4-(2,2,2-trifluoroethoxy)-pyridine 1-oxide)

CAS: 213476-12-1

Compounds containing an unfused pyridine ring in the structure, nesoi

Formula: C₁₆H₁₄F₃N₃O₃S

Color and Shape: White Powder

Molecular weight: 385.0708

Ref: 45-1A08470

Lansoprazole N-Oxide

CAS: 213476-12-1

Formula: C₁₆H₁₄F₃N₃O₃S

Purity: 95%

Color and Shape: Solid

Molecular weight: 385.3609

Ref: IN-DA00BDR6

Lansoprazole EP Impurity A (Lansoprazole N-Oxide)

CAS: 213476-12-1

Formula: C₁₆H₁₄F₃N₃O₃S

Color and Shape: White To Off-White Solid

Molecular weight: 385.37

Ref: 4Z-L-039

2-(((1H-Benzo[d]imidazol-2-yl)sulfinyl)methyl)-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine 1-oxide

CAS: 213476-12-1

2-(((1H-Benzo[d]imidazol-2-yl)sulfinyl)methyl)-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine 1-oxide

Purity: 95%

Molecular weight: 385.37g/mol

Ref: 54-PC1007602

2-[(RS)-[[3-Methyl-1-oxido-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methyl]sulphinyl]-1H-benzimidazole (Lansoprazole N-Oxide)

CAS: 213476-12-1

Formula: C₁₆H₁₄F₃N₃O₃S

Color and Shape: Neat

Molecular weight: 385.36

Ref: 86-MM0474.07

Lansoprazole EP Impurity A

CAS: 213476-12-1

Formula: C₁₆H₁₄F₃N₃O₃S

Molecular weight: 385.36

Ref: ST-EA-CP-L11001

Lansoprazole N-Oxide

Controlled Product

CAS: 213476-12-1

Impurity Lansoprazole EP Impurity A
Applications Lansoprazole N-Oxide (Lansoprazole EP Impurity A) is an impurity of Lansoprazole (L175000) formed during the bulk synthesis of the drug.
References Kubo, K., et al.: Chem. Pharm. Bull., 38, 2853 (1990), Barradell, L., et al.: Drugs, 44, 225 (1992), Aydogmus, Z., et al.: Acta Pharm. Sci., 48, 45 (2006),

Formula: C₁₆H₁₄F₃N₃O₃S

Color and Shape: Neat

Molecular weight: 385.36

Ref: TR-L175035

Lansoprazole N-oxide

CAS: 213476-12-1

Lansoprazole N-oxide is a prodrug that is converted to lansoprazole sulfone in vivo. Lansoprazole N-oxide is used as a diluent in chromatographic experiments. It has been shown to be more sensitive than the parent compound, lansoprazole, for the diagnosis of reflux oesophagitis. Lansoprazole N-oxide also has a validation wavelength of 240 nm and can be detected by liquid chromatography. The active form of lansoprazole, lansoprazole sulfone, can be detected by gas chromatography mass spectrometry (GCMS).

Formula: C₁₆H₁₄F₃N₃O₃S

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 385.36 g/mol

Ref: 3D-IL24840

Lansoprazole N-oxide

CAS: 213476-12-1

Lansoprazole N-oxide is a potential impurity in lansoprazole bulk preparations, identified as a degradation product under acidic or basic conditions. This compound is related to lansoprazole, a proton pump inhibitor.

Formula: C₁₆H₁₄F₃N₃O₃S

Color and Shape: Solid

Molecular weight: 385.36

Ref: TM-T84927