CAS 21829-25-4
:Nifedipine
Description:
Nifedipine is a calcium channel blocker primarily used in the treatment of hypertension and angina pectoris. It belongs to the dihydropyridine class of medications and works by inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle, leading to vasodilation and reduced myocardial oxygen demand. Nifedipine is typically administered in its extended-release form to provide sustained therapeutic effects. The substance is characterized by its yellow crystalline appearance and is relatively lipophilic, which influences its absorption and distribution in the body. It has a moderate solubility in water and is often formulated with various excipients to enhance its bioavailability. Nifedipine can cause side effects such as flushing, headache, and peripheral edema, and its use may be contraindicated in certain populations, such as those with severe hypotension or certain types of heart conditions. As with any medication, it is essential to use nifedipine under medical supervision to monitor for efficacy and potential adverse effects.
Formula:C17H18N2O6
InChI:InChI=1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,15,18H,1-4H3
InChI key:InChIKey=HYIMSNHJOBLJNT-UHFFFAOYSA-N
SMILES:C(OC)(=O)C=1C(C(C(OC)=O)=C(C)NC1C)C2=C(N(=O)=O)C=CC=C2
Synonyms:- 2,6-Dimethyl-3,5-dicarbomethoxy-4-(2-nitrophenyl)-1,4-dihydropyridine
- 4-(2-Nitrophenyl)-2,6-dimethyl-3,5-dicarbomethoxy-1,4-dihydropyridine
- Adalat
- Adalate
- Adapine
- Adapress
- Alat
- Aldipin
- Alfadat
- Alonix
- Angipec
- Anifed
- Anpine
- Apo-Nifed
- Aprical
- Bonacid
- Calcibloc
- Calcigard
- Calciguard
- Calcilat
- Camont
- Cardifen
- Cardilat
- Cardilate
- Cardionorm
- Chronadalate
- Citilat
- Coracten
- Coral
- Cordafen
- Cordaflex
- Cordalat
- Cordicant
- Cordilan
- Cordipin
- Cordipin-retard
- Corinfar
- Corotrend
- Corynphar
- Depin
- Dignokonstant
- Dilafed
- Dilcor
- Dipinkor
- Duranifin
- Ecodipi
- Ecodipin
- Fedcor
- Fedipin
- Fenamon
- Fenihidine
- Glopir
- Hadipine
- Hexadilat
- Introcar
- Kordafen
- Macorel
- Megalat
- Myogard
- NIfedilat
- Nedipin
- Nicardia
- Nifangin
- Nifar
- Nifdemin
- Nifebene
- Nifecard
- Nifecor
- Nifedate
- Nifedepat
- Nifedicor
- Nifedin
- Nifedine
- Nifedipin
- Nifedipino
- Nifedipres
- Nifelan
- Nifelantern
- Nifelat
- Nifelate
- Nificard
- Nifidine
- Nifipen
- Niphedipine
- Normadil
- Nyefax
- Orix
- Osmo-Adalat
- Oxcord
- Pidilat
- Procardia
- Sepamit
- Tensopin
- Tibricol
- Vasdalat
- Vasofed
- Xinran
- Zenusin
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(o-nitrophenyl)-, dimethyl ester
- Nifedipine
- BAY-a 1040
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, 3,5-dimethyl ester
- See more synonyms
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Nifedipine
CAS:Formula:C17H18N2O6Purity:>98.0%(HPLC)(E)Color and Shape:Light yellow to Yellow to Orange powder to crystalMolecular weight:346.34Nifedipine, 98%
CAS:L-type calcium channel blocker; induces apoptosis in human glioblastoma cellsFormula:C17H18N2O6Purity:98%Color and Shape:Powder or crystals or crystalline powder, YellowMolecular weight:346.34NIFEDIPINE CRS
CAS:NIFEDIPINE CRSFormula:C17H18N2O6Color and Shape:Added ModifiedMolecular weight:346.3346Nifedipine
CAS:NifedipineFormula:C17H18N2O6Purity:99.9%Color and Shape:Yellow SolidMolecular weight:346.11649Nifedipine
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFormula:C17H18N2O6Color and Shape:Yellow PowderMolecular weight:346.11649Nifedipine
CAS:Nifedipine (Procardia) is a dihydropyridine calcium channel blocking agent.Formula:C17H18N2O6Purity:99.39% - 99.88%Color and Shape:SolidMolecular weight:346.3346Nifedipine
CAS:NifedipineFormula:C17H18N2O6Purity:98%Color and Shape:Solid-PowderMolecular weight:346.337Nifedipine
CAS:Formula:C17H18N2O6Purity:≥ 98.0% (anhydrous)Color and Shape:Yellow powderMolecular weight:346.33Nifedipine-d4 (2-nitrophenyl-d4) 99% atomes enrichis96% pureté chimique
CAS:Purity:99 atom % DColor and Shape:White To Yellow SolidMolecular weight:350.36Nifedipine
CAS:Controlled ProductApplications Used as an antihypertensive and antianginal. A dihydorpyridine calcium channel blocker.
References Ali, S.L., et al.: Anal. Profiles Drug Subs., 18, 221 (1989), Soons, P.A., et al.: J. Pharm. Biomed. Anal., 9, 475 (1991), Brown, M.J., et al.: Lancet, 356, 366 (2000),Formula:C17H18N2O6Color and Shape:NeatMolecular weight:346.33Nifedipine
CAS:Â L-type calcium channel blockerFormula:C17H18N2O6Purity:Min. 98%Color and Shape:Yellow PowderMolecular weight:346.33 g/mol
