CAS 22260-51-1: Bromocriptine mesylate
Description:Bromocriptine mesylate is a synthetic compound primarily used as a dopamine agonist in the treatment of various medical conditions, including Parkinson's disease, hyperprolactinemia, and certain types of acromegaly. It is derived from ergot alkaloids and functions by stimulating dopamine receptors, particularly D2 receptors, which helps to regulate hormonal levels and improve motor control. The mesylate salt form enhances its solubility and stability, making it suitable for pharmaceutical formulations. Bromocriptine mesylate is typically administered orally and is known for its relatively rapid absorption and bioavailability. Common side effects may include nausea, dizziness, and fatigue, reflecting its central nervous system activity. The compound is classified as a prescription medication and should be used under medical supervision due to potential interactions with other drugs and contraindications in certain patient populations. Its chemical structure includes a bromine atom, contributing to its pharmacological properties, and it is often studied for its effects on neuroendocrine functions.
Formula:C32H40BrN5O5·CH4O3S
InChI:InChI=1S/C32H40BrN5O5.CH4O3S/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18;1-5(2,3)4/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39);1H3,(H,2,3,4)/t18-,23-,24+,25+,31-,32+;/m1./s1
InChI key:InChIKey=NOJMTMIRQRDZMT-GSPXQYRGSA-N
SMILES:O=C(NC1(OC2(O)N(C1=O)C(C(=O)N3CCCC32)CC(C)C)C(C)C)C4C=C5C=6C=CC=C7NC(Br)=C(C76)CC5N(C)C4.O=S(=O)(O)C
- Synonyms:
- (+)-Bromocriptine methanesulfonate
- (5'Alpha)-2-Bromo-12'-Hydroxy-5'-(2-Methylpropyl)-3',6',18-Trioxo-2'-(Propan-2-Yl)Ergotaman Methanesulfonate (1:1)
- (5Xi,5'Alpha)-2-Bromo-12'-Hydroxy-2'-(1-Methylethyl)-5'-(2-Methylpropyl)-3',6',18-Trioxoergotaman Methanesulfonate (Salt)
- (8Xi,12'Xi)-2-Bromo-12'-Hydroxy-2'-(1-Methylethyl)-5'-(2-Methylpropyl)-3',6',18-Trioxoergotaman Methanesulfonate (Salt)
- 2-bromo-A-ergocryptine methanesulfonate salt
- 8H-Oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine, ergotaman-3′,6′,18-trione deriv.
- Bagren
- Bromocriptine Mesylate
- Bromocryptine mesylate
- Bromocryptine methanesulfonate
- See more synonyms
- Cb 154
- Cycloset
- Ergocryptine, 2-bromo-, monomethanesulfonate (salt)
- Ergotaman-3′,6′,18-trione, 2-bromo-12′-hydroxy-2′-(1-methylethyl)-5′-(2-methylpropyl)-, (5α)-, methanesulfonate (1:1)
- Ergotaman-3′,6′,18-trione, 2-bromo-12′-hydroxy-2′-(1-methylethyl)-5′-(2-methylpropyl)-, (5′α)-, monomethanesulfonate (salt)
- Indolo[4,3-fg]quinoline, ergotaman-3′,6′,18-trione deriv.
- Parlodel
- Pravidel
