CAS 24390-14-5: Doxycycline hyclate

Description: Doxycycline hyclate is a broad-spectrum antibiotic belonging to the tetracycline class, primarily used to treat various bacterial infections, including respiratory tract infections, urinary tract infections, and certain skin conditions. It is characterized by its ability to inhibit protein synthesis in bacteria by binding to the 30S ribosomal subunit, thereby preventing the growth and reproduction of the microorganisms. Doxycycline hyclate is a semi-synthetic derivative of tetracycline, which enhances its stability and absorption in the gastrointestinal tract. The substance is typically administered orally and is known for its relatively long half-life, allowing for once or twice daily dosing. It is also effective against certain protozoal infections and is used in the treatment of acne and as prophylaxis for malaria. Common side effects may include gastrointestinal disturbances, photosensitivity, and potential effects on bone and teeth development in children. Due to its broad activity, doxycycline hyclate is a valuable tool in both human and veterinary medicine.

Formula: C₂₂H₂₄N₂O₈C₂H₆O·ClHH₂O

InChI: InChI=1S/C22H24N2O8.C2H6O.ClH.H2O/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;1-2-3;;/h4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31);3H,2H2,1H3;1H;1H2/t7-,10+,14+,15-,17-,22-;;;/m0.../s1

InChI key: InChIKey=JRNIHERUNQWMMW-WBYAVNBMSA-N

SMILES: Cl.O=C(N)C=1C(=O)C2(O)C(O)=C3C(=O)C=4C(O)=CC=CC4C(C)C3C(O)C2C(C1O)N(C)C.O.OCC

Synonyms:

• (1S,3Z,4aS,11R,11aR,12S,12aR)-3-[amino(hydroxy)methylidene]-4a,6,7,12-tetrahydroxy-N,N,11-trimethyl-2,4,5-trioxo-1,2,3,4,4a,5,11,11a,12,12a-decahydrotetracen-1-aminium chloride
• (2E,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione - ethanol (2:1) dihydrochloride hydrate
• (2Z,4S,4aR,5S,5aR,6R)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
• (2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione - ethanol (2:1) dihydrochloride hydrate
• (4S,4Ar,5S,5Ar,6R,12As)-4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,5,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-2-Naphthacenecarboxamide Hydrochloride
• (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide-ethanol hydrochloride hydrate (2:1:2:1)
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride, (4S,4aR,5S,5aR,6R,12aS)-, compd. with ethanol, hydrate (2:2:1:1)
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aR,5S,5aR,6R,12aS)-, compd. with ethanol (2:1), monohydrate
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, [4S-(4α,4aα,5α,5aα,6α,12aα)]-, compd. with ethanol (2:1), monohydrate
• 2-Naphthacenecarboxamide, 4β-(dimethylamino)-1,4,4aβ,5,5aβ,6,11,12a-octahydro-3,5β,10,12,12aβ-pentahydroxy-6β-methyl-1,11-dioxo-, monohydrochloride, compd. with ethyl alc. (2:1), monohydrate
• 4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,5,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-2-Na
• 4-(Dimethylamino)-3,5,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-1,4,4A,5,5A,6,11,12A-Octahydrotetracene-2-Carboxamide
• 4-(Dimethylamino)-3,5,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-1,4,4A,5,5A,6,11,12A-Octahydrotetracene-2-Carboxamide-Ethanol (2:1) Dihydrochloride Hydrate
• 6-Desoxy-5-hydroxytetracycline hydrochloride hemihydrate hemiethanolate
• Atridox
• BioPure MTAD
• Doryx
• Dox-T 100
• Doxitrat
• Doxy 100
• Doxycycline Hyclate
• Doxycycline Hyclate Monohydrate
• Doxycycline Hydrate
• Doxycycline Hydrochlocide
• Doxycycline Hydrochloride
• Doxycycline Hydrochloride Anhydrous
• Doxycycline Hydrochloride Hemiethanolate Hemihydrate
• Doxycycline hyclate COS
• Doxyprex
• Ethanol, compd. with (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride (1:2), monohydrate
• Ethanol, compd. with [4S-(4α,4aα,5α,5aα,6α,12aα)]-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride (1:2), monohydrate
• Monodoks
• Periostat
• Tetraclean
• Wc 2031

Doxycycline Hyclate

CAS: 10592-13-9 24390-14-5564-25-0

• Formula: C₂₂H₂₄N₂O₈C₂H₆O·HClH₂O
• Purity: >97.0%(HPLC)
• Color and Shape: Light yellow to Amber to Dark green powder to crystal
• Molecular weight: 512.94

Doxycycline hyclate

CAS: 24390-14-5

Inhibits matrix metalloproteinases at subantimicrobial doses.Doxycycline hyclate is an antibacterial antibiotic, which is used in …

• Formula: C₄₆H₅₈Cl₂N₄O₁₈
• Color and Shape: Powder or crystals or crystalline powder, Yellow
• Molecular weight: 1025.88

Doxycycline hyclate

CAS: 24390-14-5

• Formula: C₂₂H₂₄N₂O₈/ C₂₂H₂₅ClN₂O₈
• Purity: 83.1% / 89.9%
• Color and Shape: Yellow
• Molecular weight: 444.15327 / 480.12994

Doxycycline hyclate CRS

CAS: 24390-14-5

• Formula: C₄₆H₅₈Cl₂N₄O₁₈
• Color and Shape: Crystalline Powder. Yellow. Powder.
• Molecular weight: 1025.875

Doxycycline for system suitability CRS

CAS: 24390-14-5

• Formula: C₄₆H₅₈Cl₂N₄O₁₈
• Color and Shape: Crystalline Powder. Yellow. Powder.
• Molecular weight: 1025.875

Doxycycline Hyclate

CAS: 24390-14-5

Tetracyclines and their derivatives; salts thereof

• Formula: C₁₂H₂₄N₂O₈C₂H₆O·ClHH₂O
• Color and Shape: Light Yellow Powder
• Molecular weight: 1025.89

2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride, (4S,4aR,5S,5aR,6R,12aS)-, compd. with ethanol, hydrate (2:2:1:1)

CAS: 24390-14-5

• Formula: C₄₆H₅₈Cl₂N₄O₁₈
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 1025.8747

Doxycycline hyclate

CAS: 24390-14-5

• Formula: C₂₂H₂₄N₂O₈·HCl·5H₂O·5C₂H₆O
• Purity: 95.0 - 102.0 % (C22H25ClN2O8, anhydrous and ethanol free basis)
• Color and Shape: Yellow, crystalline powder, hygroscopic
• Molecular weight: 512.94

Doxycycline (hyclate)

CAS: 24390-14-5

• Purity: 99.17%
• Molecular weight: 512.9g/mol

Doxycycline hyclate

CAS: 24390-14-5

• Purity: 99%
• Molecular weight: 544.982g/mol

Doxycycline hyclate

CAS: 24390-14-5

• Formula: C₂₂H₂₄N₂O₈·C₂H₆OClH·H₂O
• Color and Shape: Neat
• Molecular weight: 1025.87

Doxycycline hyclate 100 µg/mL in Acetonitrile

CAS: 24390-14-5

• Formula: C₂₂H₂₄N₂O₈·C₂H₆OClH·H₂O
• Color and Shape: Single Solution
• Molecular weight: 1025.87

Doxycycline hyclate, 98%

CAS: 24390-14-5

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₄₆H₅₈Cl₂N₄O₁₈
• Purity: 98%
• Color and Shape: Powder, White to yellow
• Molecular weight: 1025.88

PharmaVetResiMix 5 Tetracyclines-v10 10 µg/mL in Methanol

CAS: 101342-45-4 14206-58-7 179471-95-5 2058-46-0 23313-80-6 24390-14-541411-66-9 64-72-2 64-73-3 64-75-5

• Color and Shape: Mixture

Doxycycline Hyclate

CAS: 24390-14-5

• Formula: C₂₂H₂₄N₂O₈·C₂H₆OClH·H₂O
• Color and Shape: Neat
• Molecular weight: 1025.87

Doxycycline (hyclate)

CAS: 24390-14-5

Doxycycline hyclate (WC2031) is a synthetic tetracycline derivative with similar antimicrobial activity. Doxycycline hyclate is …

• Formula: C₂₂H₂₄N₂O₈·HClC₂H₆OH₂O
• Purity: 100% - 99.94%
• Color and Shape: Yellow Crystallien Powder
• Molecular weight: 512.9

Doxycycline-d3 Hyclate (Major)

CAS: 24390-14-5

Applications Doxycycline-d3 Hyclate, is the labeled analogue of Doxycycline Hyclate (D561500), acting as an Antibacterial. …

• Formula: (C₂₂H₂₁D₃N₂O₈)• 2HCl•xH₂O•C₂H₆O
• Color and Shape: Yellow
• Molecular weight: 2447.452364618

Doxycycline Hyclate

CAS: 24390-14-5

Applications Antibacterial. References Fabre, et al.: Chemotherapia, 11, 73 (1966), Goldenthal, et al.: Toxicol. Appl. …

• Formula: C₂₂H₂₄N₂O₈·C₂H₆OClH·H₂O
• Color and Shape: Yellow
• Molecular weight: 1025.87

Doxycycline hyclate - Bio-X ™

CAS: 24390-14-5

Doxycycline is a tetracycline antibiotic that is used to treat a range of bacterial infections. …

• Formula: C₂₂H₂₄N₂O₈•HCl•(C₂H₆O)₀•(H₂O)₀
• Purity: Min. 95 Area-%
• Color and Shape: Powder
• Molecular weight: 512.94 g/mol

Doxycycline hyclate

CAS: 24390-14-5

Antibiotic; anti-protozoal; anti-helmintic; protein synthesis inhibitor

• Formula: C₂₂H₂₄N₂O₈•HCl•(C₂H₆O)₀•(H₂O)₀
• Purity: Min. 95 Area-%
• Color and Shape: Yellow Powder
• Molecular weight: 512.94 g/mol