CAS 25389-94-0: Kanamycin sulfate

Description:Kanamycin sulfate is an aminoglycoside antibiotic derived from the bacterium Micromonospora kanamycetica. It is primarily used to treat infections caused by certain types of bacteria, particularly those resistant to other antibiotics. Kanamycin sulfate is characterized by its ability to inhibit bacterial protein synthesis by binding to the 30S ribosomal subunit, which disrupts the translation process. This antibiotic is effective against a range of Gram-negative and some Gram-positive bacteria. In its sulfate form, it is more soluble in water, enhancing its bioavailability for therapeutic use. Kanamycin sulfate is typically administered via injection or infusion, and its use is associated with potential side effects, including nephrotoxicity and ototoxicity, necessitating careful monitoring of kidney function and hearing during treatment. Additionally, resistance to kanamycin can develop, making susceptibility testing important in clinical settings. Overall, kanamycin sulfate remains a valuable option in the antibiotic arsenal, particularly for treating serious infections where other treatments may fail.

Formula:C₁₈H₃₆N₄O₁₁·H₂O₄S

InChI:InChI=1S/C18H36N4O11.H2O4S/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17;1-5(2,3)4/h4-18,23-29H,1-3,19-22H2;(H2,1,2,3,4)/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-;/m1./s1

InChI key:InChIKey=OOYGSFOGFJDDHP-KMCOLRRFSA-N

SMILES:O=S(=O)(O)O.OCC1OC(OC2C(O)C(OC3OC(CN)C(O)C(O)C3O)C(N)CC2N)C(O)C(N)C1O

Synonyms:
(1R,2S,3S,4R,6R)-4,6-Diamino-3-[(3-amino-3-deoxy-α-D-glucopyranosyl)oxy]-2-hydroxycyclohexyl 6-amino-6-deoxy-α-L-galactopyranoside sulfate (salt)
(1S,2R,3R,4S,6R)-4,6-diamino-3-[(6-amino-6-deoxy-alpha-D-glucopyranosyl)oxy]-2-hydroxycyclohexyl 3-amino-3-deoxy-alpha-D-glucopyranoside sulfate (1:1)
(1S,2R,4S,6R)-4,6-diamino-3-[(6-amino-6-deoxy-α-D-glucopyranosyl)oxy]-2-hydroxycyclohexyl 3-amino-3-deoxy-α-D-glucopyranoside sulfate (salt)
(2S,3S,4R,5S,6S)-2-(aminomethyl)-6-[(1R,2S,3S,4R,6R)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]tetrahydropyran-3,4,5-triol,sulfuric acid
4,6-Diamino-3-[(6-Amino-6-Deoxyhexopyranosyl)Oxy]-2-Hydroxycyclohexyl 3-Amino-2,3-Dideoxyhexopyranoside Sulfate (1:1)
4,6-Diamino-3-[(6-Amino-6-Deoxyhexopyranosyl)Oxy]-2-Hydroxycyclohexyl 3-Amino-3-Deoxyhexopyranoside Sulfate (1:1)
<span class="text-smallcaps">D</smallcap>-Streptamine, O-3-amino-3-deoxy-α-<smallcap>D</smallcap>-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-<smallcap>D</span>-glucopyranosyl-(1→4)]-2-deoxy-, sulfate (1:1)
<span class="text-smallcaps">D</smallcap>-Streptamine, O-3-amino-3-deoxy-α-<smallcap>D</smallcap>-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-<smallcap>D</span>-glucopyranosyl-(1→4)]-2-deoxy-, sulfate (1:1) (salt)
Cantrex
Cristalomicina
See more synonyms
Enterokanacin
Kamycin
Kanabristol
Kanacedin
Kanachron
Kanamycin A monosulfate
Kanamycin A sulfate
Kanamycin Mono Sulphate
Kanamycin Monosulfate
Kanamycin Monosulfate Salt
Kanamycin Solution Hybri-Max
Kanamycin Sulfate
Kanamycin Sulfate Salt
Kanamycin Sulfate Usp
Kanamycin Sulfate White
Kanamycin, sulfate (1:1) (salt)
Kanamytrex
Kanaqua
Kanasig
Kanatrol
Kanescin
Kanicin
Kannasyn
Kantrex
Kantrexil
Kantrim
Kantrox
Kasmynex
Kenendomycin
Klebcil
Ophtalmokalixan
Otokalixin
Resistomycin
α-L-galactopyranoside, (1R,2S,3S,4R,6R)-4,6-diamino-3-[(3-amino-3-deoxy-α-D-glucopyranosyl)oxy]-2-hydroxycyclohexyl 6-amino-6-deoxy-, sulfate (1:1) (salt)
D-Streptamine, O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-, sulfate (1:1) (salt)
D-Streptamine, O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-, sulfate (1:1)

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Product data	Purity	Price range	Estimated delivery
Kanamycin Monosulfate REF: 3B-K0047CAS: 25389-94-0 59-01-8 8063-07-8	>94.0%(N)	39.00 €~107.00 €	Wed 12 Mar 25
Kanamycin monosulfate REF: 02-J61272CAS: 25389-94-0	- - -	To inquire	Thu 13 Mar 25
Kanamycin Sulfate, Ultrapure REF: 02-J17924CAS: 25389-94-0	- - -	To inquire	Thu 13 Mar 25
Kanamycin monosulfate, Cell Culture Grade REF: 02-J60668CAS: 25389-94-0	- - -	59.00 €~158.00 €	Thu 13 Mar 25
Kanamycin, 50 mg/ml in distilled water, sterile-filtered REF: 02-J67354CAS: 25389-94-0	- - -	225.00 €~289.00 €	Thu 13 Mar 25
Kanamycin sulfate REF: AC-45081CAS: 25389-94-0	- - -	228.00 €~1,162.00 €	Mon 17 Mar 25
Kanamycin monosulfate CRS REF: 41-K0200000CAS: 25389-94-0	- - -	115.00 €	Mon 17 Mar 25
First International Standard for Kanamycin REF: 41-ISA_83_521CAS: 25389-94-0	- - -	115.00 €	Mon 17 Mar 25
Kanamycin monosulfate REF: 47-861CAS: 25389-94-0	- - -	211.00 €	Mon 17 Mar 25
Kanamycin sulfate REF: IN-DA00352LCAS: 25389-94-0	95%	21.00 €~126.00 €	Wed 19 Mar 25
Kanamycin sulphate (1:1) REF: 54-BIK0126CAS: 25389-94-0	98.2% (Typical Value in Batch COA)	84.00 €~344.00 €	Thu 20 Mar 25
Kanamycin monosulfate salt REF: 7W-GA0531CAS: 25389-94-0	≥ 750µg/g (dried basis)	27.00 €~156.00 €	Thu 20 Mar 25
Kanamycin sulfate 100 µg/mL in Water REF: 04-A14505520WA-100CAS: 25389-94-0	- - -	To inquire	Mon 24 Mar 25
Kanamycin Sulfate, Streptomyces kanamyceticus REF: 10-M02038CAS: 25389-94-0	>680 u/mg	20.00 €~158.00 €	Mon 24 Mar 25
Kanamycin sulfate REF: 04-C14505520CAS: 25389-94-0	- - -	64.00 €	Mon 24 Mar 25
Kanamycin A Sulfate REF: 4Z-K-012009CAS: 25389-94-0	- - -	To inquire	Wed 26 Mar 25
Kanamycin Solution (100mg/ml) REF: 54-BIG1036CAS: 25389-94-0	- - -	96.00 €~286.00 €	Wed 26 Mar 25
Kanamycin A-d2 Sulfate REF: 4Z-K-012007CAS: 25389-94-0	- - -	To inquire	Wed 26 Mar 25
Kanamycin sulfate REF: TM-T0793CAS: 25389-94-0	99.63% - 99.96%	48.00 €~55.00 €	Wed 26 Mar 25
Kanamycin (50mg/ml) REF: 54-BIG1030CAS: 25389-94-0	- - -	To inquire	Wed 26 Mar 25