CAS 25953-19-9: Cefazolin

Description: Cefazolin is a first-generation cephalosporin antibiotic, primarily used for the treatment of bacterial infections. It is effective against a variety of gram-positive bacteria and some gram-negative organisms. Cefazolin works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. The compound is typically administered via injection, as it is not well absorbed from the gastrointestinal tract. Its chemical structure includes a beta-lactam ring, which is essential for its antibacterial activity. Cefazolin is often used in surgical prophylaxis and for treating infections such as skin and soft tissue infections, urinary tract infections, and respiratory tract infections. It is generally well-tolerated, but potential side effects may include allergic reactions, gastrointestinal disturbances, and alterations in blood clotting. As with all antibiotics, it is crucial to use cefazolin judiciously to prevent the development of antibiotic resistance. Its CAS number, 25953-19-9, uniquely identifies this compound in chemical databases.

Formula: C₁₄H₁₄N₈O₄S₃

InChI: InChI=1S/C14H14N8O4S3/c1-6-17-18-14(29-6)28-4-7-3-27-12-9(11(24)22(12)10(7)13(25)26)16-8(23)2-21-5-15-19-20-21/h5,9,12H,2-4H2,1H3,(H,16,23)(H,25,26)/t9-,12-/m1/s1

InChI key: InChIKey=MLYYVTUWGNIJIB-BXKDBHETSA-N

SMILES: O=C(O)C1=C(CSC2=NN=C(S2)C)CSC3N1C(=O)C3NC(=O)CN4N=NN=C4

Synonyms:

• (6R,7R)-3-[[(5-Methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[[2-(1H-tetrazol-1-yl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R-trans)-3-[[(5-Methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[[(1H-tetrazol-1-yl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[(1H-tetrazol- 1-ylacetyl)amino]-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-, (6R-trans)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[2-(1H-tetrazol-1-yl)acetamido]-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[[2-(1H-tetrazol-1-yl)acetyl]amino]-, (6R,7R)-
• 7-(1-(1H)-Tetrazolylacetamido)-3-[2-(5-methyl-1,3,4-thiadiazolyl)thiomethyl]-Δ3-cephem-4-carboxylic acid
• 7-(1-(1H)-Tetrazolylacetamido)-3-[2-(5-methyl-1,3,4-thiadiazolyl)thiomethyl]-Δ³-cephem-4-carboxylic acid
• 7-(1H-Tetrazol-1-ylacetamido)-3-(5-methyl-1,3,4-thiadiazol-2-yl)thiomethyl-3-cephem-4-carboxylic acid
• 7-[1-(1H)-tetrazolylacetoamido]-3-[2-(5-methyl-1,3,4-thiadiazolyl)-thiomethyl]-Δ-3-cephem-4-carboxylic acid
• CEZ
• Cefamedin
• Cefamezin
• Cefaprim
• Cefazolin,sodium salt
• Cefazolina
• Cefazoline
• Cephamezine
• Cephazolin
• Cephazolin,sodium salt
• Cephazoline
• Elzogram
• Sefazol
• Zinol

Cefazolin Sodium Salt

CAS: 25953-19-927164-46-1

• Formula: C₁₄H₁₃N₈NaO₄S₃
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Orange to Green powder to crystal
• Molecular weight: 476.48

Cefazolin CRS

CAS: 25953-19-9

• Formula: C₁₄H₁₄N₈O₄S₃
• Molecular weight: 454.5072

Cefazolin

CAS: 25953-19-9

Antibiotics nesoi

• Formula: C₁₄H₁₄N₈O₄S₃
• Color and Shape: White Powder
• Molecular weight: 454.51

Cefazolin

CAS: 25953-19-9

• Formula: C₁₄H₁₄N₈O₄S₃
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 454.5072

Cefazolin Impurity 45

CAS: 2101505-58-0 25953-19-9

• Formula: C₁₃H₁₄N₆O₆S
• Color and Shape: White To Off-White Solid
• Molecular weight: 382.35

Cefazolin

CAS: 25953-19-9

• Formula: C₁₄H₁₄N₈O₄S₃
• Purity: ≥ 98.0% (dry basis)
• Color and Shape: White to off-white powder
• Molecular weight: 454.51

Cefazolin

CAS: 25953-19-9

• Purity: 99%
• Molecular weight: 454.51g/mol

Cefazolin 1000 µg/mL in Acetonitrile

CAS: 25953-19-9

• Formula: C₁₄H₁₄N₈O₄S₃
• Color and Shape: Single Solution
• Molecular weight: 454.51

Cefazolin

CAS: 25953-19-9

Cefazolin is a semi-synthetic cephalosporin that has a broad spectrum of antibacterial activity and inhibits …

• Formula: C₁₄H₁₄N₈O₄S₃
• Purity: 99.51%
• Color and Shape: Needles From Aqueous Acetone Solid
• Molecular weight: 454.51

Cefazolin RS

CAS: 25953-19-9

• Color and Shape: White To Pale Yellowish White Solid Crystalline Powder

Cefazolin

CAS: 25953-19-9

Applications Cefazolin is an antibacterial compound derived from 7-amino-cephalosporanic acid. References Kozatani, et al.: Chem. …

• Formula: C₁₄H₁₄N₈O₄S₃
• Color and Shape: White To Off-White
• Molecular weight: 454.51

L-Cefazolin

CAS: 25953-19-9

• Formula: C₁₄H₁₄N₈O₄S₃
• Color and Shape: Neat
• Molecular weight: 454.507

Cefazolin, Antibiotic for Culture Media Use Only

CAS: 25953-19-9

Cefazolin is a semi-synthetic, non-beta lactam antibiotic used for the treatment of a variety of …

• Formula: C₁₄H₁₄N₈O₄S₃
• Molecular weight: 454.51 g/mol

Cefazolin

CAS: 25953-19-9

Cefazolin is a broad-spectrum antibiotic that inhibits the growth of Gram-positive and Gram-negative bacteria. It …

• Formula: C₁₄H₁₄N₈O₄S₃
• Purity: Min. 95%
• Molecular weight: 454.51 g/mol