CAS 27164-46-1: Cefazolin sodium

Description: Cefazolin sodium is a first-generation cephalosporin antibiotic, primarily used for the treatment of bacterial infections. It is effective against a variety of gram-positive bacteria and some gram-negative organisms. The compound is characterized by its beta-lactam structure, which is essential for its antibacterial activity. Cefazolin is typically administered via injection, as it is not well absorbed when taken orally. It has a relatively long half-life, allowing for less frequent dosing compared to some other antibiotics. The sodium salt form enhances its solubility in water, making it suitable for intravenous or intramuscular administration. Common indications for cefazolin include surgical prophylaxis and the treatment of skin, bone, and joint infections. While generally well-tolerated, it can cause side effects such as allergic reactions, gastrointestinal disturbances, and, in rare cases, nephrotoxicity. As with all antibiotics, it is crucial to use cefazolin judiciously to prevent the development of antibiotic resistance.

Formula: C₁₄H₁₄N₈O₄S₃·Na

InChI: InChI=1S/C14H14N8O4S3.Na/c1-6-17-18-14(29-6)28-4-7-3-27-12-9(11(24)22(12)10(7)13(25)26)16-8(23)2-21-5-15-19-20-21;/h5,9,12H,2-4H2,1H3,(H,16,23)(H,25,26);/t9-,12-;/m1./s1

InChI key: InChIKey=BXZNAOVMWGRSJT-WYUVZMMLSA-N

SMILES: [Na].O=C(O)C1=C(CSC2=NN=C(S2)C)CSC3N1C(=O)C3NC(=O)CN4N=NN=C4

Synonyms:

• 3-[[(5-Methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-7-[2-(1H-tetrazol-1-yl)-acetamido]-3-cephem-4-carboxylic acid sodium salt
• 3-[[(5-Methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[2-(1H-tetrazol-1-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-, monosodium salt, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-, monosodium salt, (6R-trans)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[2-(1H-tetrazol-1-yl)acetamido]-, monosodium salt
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[[2-(1H-tetrazol-1-yl)acetyl]amino]-, sodium salt (1:1), (6R,7R)-
• Ancef
• Atirin
• Azolin
• Biazolina
• Bor-Cefazol
• Cefacidal
• Cefamedin
• Cefazil
• Cefazina
• Cefazoliin
• Cefazolin Sodium
• Cefazoline sodium
• Cefazorin DC
• Cephazolin sodium
• Cephazolin sodium salt
• Firmacef
• Gramaxin
• Iespor
• Kefzol
• Lampocef
• Liviclina
• Monosodium cafazolin
• NSC 291561
• Reflin
• Skf 41558
• Sodium CEZ
• Sodium cefazolin
• Sodium cephazolin
• Totacef
• Zolicef
• sodium (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• sodium 3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• Cefazolin, Sodium Salt
• sodiumcefazolin
• sodiumcephazolin
• CEFAZOLIN NA
• (6r-trans
• sodiumcez
• cezsodium
• monosodiumcefazolin

Cefazolin Sodium Salt

CAS: 25953-19-9 27164-46-1

• Formula: C₁₄H₁₃N₈NaO₄S₃
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Orange to Green powder to crystal
• Molecular weight: 476.48

Cefazolin sodium salt

CAS: 27164-46-1

Inhibits bacterial cell wall synthesis This Thermo Scientific Chemicals brand product was originally part of …

• Formula: C₁₄H₁₃N₈NaO₄S₃
• Color and Shape: White to off-white crystalline powder
• Molecular weight: 476.48

Cefazolin sodium

CAS: 27164-46-1

Cefazolin sodium, a beta-lactam antibiotic, targets PBPs to disrupt bacterial cell wall synthesis, causing cell …

• Formula: C₁₄H₁₃N₈NaO₄S₃
• Purity: 98.38%
• Color and Shape: Yellowish-White Odorless Crystalline Powder
• Molecular weight: 476.48

Cefazolin sodium

CAS: 27164-46-1

• Formula: C₁₄H₁₃N₈NaO₄S₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 476.48898999999994

Cefazolin sodium

CAS: 27164-46-1

• Purity: ≥98%
• Molecular weight: 476.48g/mol

Cefazolin Sodium Salt

CAS: 27164-46-1

• Formula: C₁₄H₁₃N₈O₄S₃·Na
• Color and Shape: White To Off-White Solid
• Molecular weight: 453.50 22.99

Cefazolin sodium salt

CAS: 27164-46-1

• Formula: C₁₄H₁₃N₈NaO₄S₃
• Purity: ≥ 90.0%
• Color and Shape: White to off-white crystalline powder
• Molecular weight: 476.49

Cefazolin sodium salt, Ph. Eur. grade

CAS: 27164-46-1

• Formula: C₁₄H₁₃N₈NaO₄S₃
• Purity: ≤ 1.0%
• Color and Shape: White or almost white powder
• Molecular weight: 476.49

Cefazolin sodium salt

CAS: 27164-46-1

• Formula: C₁₄H₁₃N₈O₄S₃·Na
• Color and Shape: white to off-white powder
• Molecular weight: 476.49g/mol

Cefazolin sodium

CAS: 27164-46-1

• Formula: C₁₄H₁₃N₈O₄S₃·Na
• Color and Shape: Neat
• Molecular weight: 476.49

Cefazolin Sodium

CAS: 27164-46-1

• Formula: C₁₄H₁₃N₈O₄S₃·Na
• Color and Shape: Neat
• Molecular weight: 476.49

PharmaVetResiMix 6 Betalactams-v23 0.2-2.5 µg/mL in Water:Acetonitrile

CAS: 10206-21-0 104557-24-6 113-98-4 118443-89-3 132-98-9 13412-64-1 1385046-35-4 23325-78-2 24356-60-3 27164-46-150370-12-2 56238-63-2 61336-70-7 61477-96-1 62893-20-3 63358-49-6 68373-14-8 7081-44-9 7177-48-2 7240-38-2 80370-57-6 89786-04-9 985-16-0

• Color and Shape: Mixture

Cefazolin sodium

CAS: 27164-46-1

• Formula: C₁₄H₁₄N₈O₄S₃
• Purity: 91.5%
• Color and Shape: White
• Molecular weight: 454.03001

Cefazolin Sodium Salt

CAS: 27164-46-1

Applications Semi-synthetic antibiotic derived from 7-amino-cephalosporanic acid. An antibacterial. References Kozatani, et al.: Chem. Pharm. …

• Formula: C₁₄H₁₃N₈O₄S₃·Na
• Color and Shape: White
• Molecular weight: 476.49

Cefazolin Sodium

CAS: 27164-46-1

• Purity: 97.0%
• Color and Shape: Solid
• Molecular weight: 476.48

Cefazolin-13C2,15N Sodium Salt

CAS: 27164-46-1

Applications Labelled Cefazolin (C242500). Semi-synthetic antibiotic derived from 7-amino-cephalosporanic acid. An antibacterial. References Kozatani, et …

• Formula: C₁₂₁₃C₂H₁₃N₇₁₅NNaO₄S₃
• Color and Shape: Light Yellow
• Molecular weight: 479.47

Cefazolin sodium

CAS: 27164-46-1

Cefazolin sodium is a first-generation cephalosporin antibiotic with action on bacterial cell wall synthesis and …

• Formula: C₁₄H₁₃N₈NaO₄S₃
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 476.49 g/mol

Cefazolin Sodium Salt (CFZL), 89-110%

CAS: 27164-46-1

• Formula: C₁₄H₁₃N₈NaO₄S₃
• Purity: 89 - 110%
• Color and Shape: White to off-white, Powder, Clear
• Molecular weight: 476.49

7-epi-Cefazolin Sodium Salt

CAS: 27164-46-1

• Formula: C₁₄H₁₃N₈O₄S₃·Na
• Color and Shape: Neat
• Molecular weight: 476.49

Cefazolin sodium salt, 98%

CAS: 27164-46-1

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₄H₁₃N₈NaO₄S₃
• Purity: 98%
• Color and Shape: White to yellow, Powder
• Molecular weight: 476.48