CAS 26807-65-8

Indapamide

Description:

Indapamide is a thiazide-like diuretic primarily used in the treatment of hypertension and edema associated with heart failure. It is characterized by its ability to inhibit sodium reabsorption in the distal convoluted tubule of the nephron, leading to increased urine output and decreased blood pressure. Indapamide is known for its relatively long half-life, allowing for once-daily dosing, which enhances patient compliance. The compound is typically administered in oral form and is often favored for its additional vasodilatory effects, which can contribute to its antihypertensive properties. Indapamide is also distinguished by its low potential for electrolyte imbalance compared to traditional thiazide diuretics, making it a preferred choice in certain patient populations. Its chemical structure includes a sulfonamide group, which is integral to its mechanism of action. As with any medication, potential side effects may include dizziness, electrolyte disturbances, and gastrointestinal issues, necessitating monitoring during treatment.

Formula: C₁₆H₁₆ClN₃O₃S

InChI: InChI=1S/C16H16ClN3O3S/c1-10-8-11-4-2-3-5-14(11)20(10)19-16(21)12-6-7-13(17)15(9-12)24(18,22)23/h2-7,9-10H,8H2,1H3,(H,19,21)(H2,18,22,23)

InChI key: InChIKey=NDDAHWYSQHTHNT-UHFFFAOYSA-N

SMILES: N(C(=O)C1=CC(S(N)(=O)=O)=C(Cl)C=C1)N2C=3C(CC2C)=CC=CC3

Synonyms:

• 1-(4-Chloro-3-Sulfamoylbenzamido)-2-Methylindoline
• 3-(Aminosulfonyl)-4-Chloro-N-(2,3-Dihydro-2-Methyl-1H-Indol-1-Yl)-Benzamid
• 3-(Aminosulfonyl)-4-Chloro-N-(2,3-Dihydro-2-Methyl-1H-Indol-1-Yl)Benzamide
• 4-Chloro-N-(2-Methyl-1-Indolinyl)-3-Sulfamoyl-Benzamid
• 4-Chloro-N-(2-Methyl-1-Indolinyl)-3-Sulfamoylbenzamide
• 4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-sulfamoylbenzamide
• Arifon
• Bajaten
• Benzamide, 3-(aminosulfonyl)-4-chloro-N-(2,3-dihydro-2-methyl-1H-indol-1-yl)-
• Benzamide, 4-chloro-N-(2-methyl-1-indolinyl)-3-sulfamoyl-
• Damide
• Flubest
• Fludex
• Fludin
• Flupamid
• Indaflex
• Indamide
• Indamol
• Indapamid
• Indapamida
• Indapamidum
• Indaparnide
• Ipamix
• Kyd 041
• Lorvas
• Lozol
• N-(4-chloro-3-sulfamoylbenzamido)-2-methylindoline
• N-[4-chloro-3-sulfamoyl-benzamidol]-2-methylindoline
• Natrilix
• Natrix
• Noranat
• Racemic indapamide
• S 1520
• S1520
• Se-1520
• Tandix
• Tertensif
• Veroxil

Indapamide

CAS: 26807-65-8

Formula: C₁₆H₁₆ClN₃O₃S

Purity: >97.0%(T)(HPLC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 365.83

Ref: 3B-I0730

Indapamide

CAS: 26807-65-8

Used as an antihypertensive. Diuretic This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part

Formula: C₁₆H₁₆ClN₃O₃S

Molecular weight: 365.83

Ref: 02-J63846

Indapamide 1.0 mg/ml in Methanol

CAS: 26807-65-8

Color and Shape: Single Solution

Ref: 61-AMP0477.00-01

Indapamide

CAS: 26807-65-8

Color and Shape: Neat

Ref: 61-FOR0477.00

INDAPAMIDE CRS

CAS: 26807-65-8

INDAPAMIDE CRS

Formula: C₁₆H₁₆ClN₃O₃S

Color and Shape: White. Powder.

Molecular weight: 365.8345

Ref: 41-I0150000

Indapamide

CAS: 26807-65-8

Indapamide

Formula: C₁₆H₁₆ClN₃O₃S

Purity: 97.8%

Color and Shape: White To Off-White

Molecular weight: 365.06009

Ref: 47-999

Indapamide

CAS: 26807-65-8

Sulfonamides used as drugs

Formula: C₁₆H₁₆ClN₃O₃S

Color and Shape: White Off-White Powder

Molecular weight: 365.06009

Ref: 45-1338801

Indapamide

CAS: 26807-65-8

Formula: C₁₆H₁₆ClN₃O₃S

Purity: ≥ 98.0%

Color and Shape: White or off-white powder

Molecular weight: 365.83

Ref: 7W-GP2749

Indapamide-13C-d3

CAS: 26807-65-8

Formula: C₁₅₁₃CH₁₃D₃ClN₃O₃S

Color and Shape: White To Off-White Solid

Molecular weight: 369.84

Ref: 4Z-I-1329

Indapamide

CAS: 26807-65-8

Formula: C₁₆H₁₆ClN₃O₃S

Color and Shape: White To Off-White Solid

Molecular weight: 365.83

Ref: 4Z-I-1311

(RS)-Indapamide

CAS: 26807-65-8

Color and Shape: Neat

Ref: 04-C14288200

Indapamide

Controlled Product

CAS: 26807-65-8, 63968-75-2

Formula: C₁₆H₁₄ClN₃O₃S

Color and Shape: Neat

Molecular weight: 363.82

Ref: 86-MM0477.00

Indapamide RS

CAS: 26807-65-8

Color and Shape: White Solid Crystalline Powder

Ref: 2K-1017500021

rac Indapamide

CAS: 26807-65-8

Applications Used as an antihypertensive. Diuretic.
References Leary, et al.: Curr. Ther. Res., 15, 571 (1973), Kyncl, J., et al.: Arzneim.-Forsch., 25, 1491 (1975), DiFeo, T.J., et al.: Anal. Profiles Drug Subs. Excip., 23, 229 (1994),

Formula: C₁₆H₁₆ClN₃O₃S

Color and Shape: White To Off-White

Molecular weight: 365.83

Ref: TR-I500100

Indapamide - Bio-X ™

Controlled Product

CAS: 26807-65-8

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formula: C₁₆H₁₆ClN₃O₃S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 365.84 g/mol

Ref: 3D-BI300090

Indapamide

Controlled Product

CAS: 26807-65-8

Indapamide is an antihypertensive drug that inhibits the activity of the enzyme carbonic anhydrase, which is involved in the conversion of carbon dioxide to bicarbonate. It is used to treat high blood pressure and congestive heart failure. Indapamide has been shown to be effective in reducing oxidative injury to red blood cells and preventing cardiovascular events such as stroke and heart attack. Indapamide also has a long-term efficacy with no withdrawal symptoms or rebound hypertension when it is discontinued.

Formula: C₁₆H₁₆ClN₃O₃S

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 365.84 g/mol

Ref: 3D-FI01202

Indapamide

CAS: 26807-65-8

Indapamide (Noranat) is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.

Formula: C₁₆H₁₆ClN₃O₃S

Purity: 98.97% - 99.83%

Color and Shape: Solid

Molecular weight: 365.83

Ref: TM-T1498

Indapamide

CAS: 26807-65-8

Formula: C₁₆H₁₆ClN₃O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 365.8345

Ref: IN-DA003AXB