CAS 28610-31-3

Desmethylicaritin

Description:

Desmethylicaritin, with the CAS number 28610-31-3, is a flavonoid compound that is primarily derived from various plant sources, particularly those in the legume family. It is known for its potential antioxidant properties, which can help in neutralizing free radicals and reducing oxidative stress in biological systems. This compound exhibits a range of biological activities, including anti-inflammatory and antimicrobial effects, making it of interest in pharmacological research. Desmethylicaritin is typically characterized by its polyphenolic structure, which contributes to its reactivity and interaction with various biological targets. Additionally, it may influence various metabolic pathways, although further studies are needed to fully elucidate its mechanisms of action and therapeutic potential. Its solubility and stability can vary depending on the solvent and environmental conditions, which is important for its application in both research and potential therapeutic contexts. Overall, Desmethylicaritin represents a promising area of study within natural product chemistry and its applications in health and medicine.

Formula: C₂₀H₁₈O₆

InChI: InChI=1S/C20H18O6/c1-10(2)3-8-13-14(22)9-15(23)16-17(24)18(25)19(26-20(13)16)11-4-6-12(21)7-5-11/h3-7,9,21-23,25H,8H2,1-2H3

InChI key: InChIKey=NADCVNHITZNGJU-UHFFFAOYSA-N

SMILES: C(C=C(C)C)C1=C2C(C(=O)C(O)=C(O2)C3=CC=C(O)C=C3)=C(O)C=C1O

Synonyms:

• 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
• 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-enyl)chromen-4-one
• 4'-Desmethylicaritin
• 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-butenyl)-
• 4H-1-Benzopyran-4-one,3,5,7-trihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-butenyl)- (9CI)
• 8-C-Prenylkaempferol
• 8-Prenylkaempferol
• De-O-methylanhydroicaritin
• Desmethylanhydroicaritin
• Desmethylicaritin
• Flavone, 3,4′,5,7-tetrahydroxy-8-(3-methyl-2-butenyl)-
• Flavone,3,4',5,7-tetrahydroxy-8-(3-methyl-2-butenyl)- (8CI)
• Noranhydroicaritin
• 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-
• Icariin Impurity 4
• IcariinImpurity5

4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-

CAS: 28610-31-3

Formula: C₂₀H₁₈O₆

Color and Shape: Solid

Molecular weight: 354.3533

Ref: IN-DA002VUX

8-Prenylkaempferol

CAS: 28610-31-3

8-Prenylkaempferol reduces inflammation by hindering NO production, PI3K/NF-κB/IRF-3 pathways, and inhibiting IκB degradation, lessening NF-κB movement.

Formula: C₂₀H₁₈O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 354.35

Ref: TM-TN1347

Desmethyl Icaritin

CAS: 28610-31-3

Formula: C₂₀H₁₈O₆

Purity: 95%~99%

Color and Shape: Yellow powder

Molecular weight: 354.358

Ref: BP-SBP02929

Icariin Impurity 5 (Desmethyl Icaritin)

CAS: 28610-31-3

Formula: C₂₀H₁₈O₆

Molecular weight: 354.35

Ref: 4Z-I-080007

Desmethyl icaritin

CAS: 28610-31-3

Desmethyl icaritin is a naturally occurring compound, which is a bioactive metabolite derived from the plant species of the Epimedium genus, commonly known as Horny Goat Weed. These plants are widely studied for their phytoestrogenic compounds, particularly in traditional herbal medicine.

Formula: C₂₀H₁₈O₆

Purity: Min. 97 Area-%

Color and Shape: Powder

Molecular weight: 354.35 g/mol

Ref: 3D-FD15444

Desmethyl Icaritin

Controlled Product

CAS: 28610-31-3

Applications A metabolite of Icariin. Icaritin and Desmethylicaritin, two metabolites of Icariin, dramatically inhibit the growth of most malignant cells. They also have significant antiangiogenesis properties, inhibiting or eliminating entirely the development of new malignant cells.
References Carmichael, J; Cancer Res 1987, 47, 943,,,Franke, T; Science 1997, 275, 665,,,Kowalski, J; Pharmacol Rep 2005, 57, 390,,,Lee, G; Eur J Pharmacol 2006, 551, 143,,,

Formula: C₂₀H₁₈O₆

Color and Shape: Neat

Molecular weight: 354.35

Ref: TR-D291760