CAS 28657-80-9: Cinoxacin

Description: Cinoxacin is a synthetic antibiotic belonging to the fluoroquinolone class, primarily used for the treatment of urinary tract infections. Its chemical structure features a bicyclic core that includes a quinolone moiety, which is essential for its antibacterial activity. Cinoxacin exhibits broad-spectrum activity against various Gram-negative and some Gram-positive bacteria by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and transcription. The substance is characterized by its relatively low solubility in water, which can affect its bioavailability. It is typically administered orally and is metabolized in the liver, with renal excretion of its metabolites. Common side effects may include gastrointestinal disturbances, central nervous system effects, and potential allergic reactions. Due to the emergence of antibiotic resistance, the use of cinoxacin has declined in favor of newer fluoroquinolones with improved efficacy and safety profiles. As with all antibiotics, it is crucial to use cinoxacin judiciously to minimize resistance development.

Formula: C₁₂H₁₀N₂O₅

InChI: InChI=1S/C12H10N2O5/c1-2-14-7-4-9-8(18-5-19-9)3-6(7)11(15)10(13-14)12(16)17/h3-4H,2,5H2,1H3,(H,16,17)

InChI key: InChIKey=VDUWPHTZYNWKRN-UHFFFAOYSA-N

SMILES: O=C(O)C1=NN(C2=CC=3OCOC3C=C2C1=O)CC

Synonyms:

• (1,3)Dioxolo(4,5-g)cinnoline-3-carboxylic acid, 1,4-dihydro-1-ethyl-4-oxo-
• (1,3)Dioxolo(4,5-g)cinnoline-3-carboxylic acid, 1-ethyl-1,4-dihydro-4-oxo-
• 1-Ethyl-1,4-dihydro-4-oxo(1,3)dioxolo(4,5-g)cinnoline-3-carboxylic acid
• 1-Ethyl-3-carboxy-6,7-methylenedioxy-4-cinnolone
• 1-Ethyl-4-Oxo-1,4-Dihydro[1,3]Dioxolo[4,5-G]Cinnoline-3-Carboxylic Acid
• 1-Ethyl-4-oxo-1H,4H,7H-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid
• 1-Ethyl-6,7-methylenedioxy-4(1H)-oxocinnoline-3-carboxylic acid
• Brn 1084304
• Ccris 8206
• Cinobac
• Cinobactin
• Cinoxacin [USAN:INN:BAN:JAN]
• Cinoxacine
• Cinoxacine [INN-French]
• Cinoxacino
• Cinoxacino [INN-Spanish]
• Cinoxacinum
• Cinoxacinum [INN-Latin]
• Compound 64716
• Lilly 64716
• Noxigram
• Nsc 304467
• Unii-Lmk22Vuh23
• Uronorm
• Cinoxacin
• Cinoxacin

Cinoxacin

CAS: 28657-80-9

Cinoxacin (Compound 64716), an older synthetic antimicrobial, was related to the quinolone class of antibiotics.

• Formula: C₁₂H₁₀N₂O₅
• Purity: 99.62% - 99.98%
• Color and Shape: Solid
• Molecular weight: 262.22

[1,3]Dioxolo[4,5-g]cinnoline-3-carboxylic acid, 1-ethyl-1,4-dihydro-4-oxo-

CAS: 28657-80-9

• Formula: C₁₂H₁₀N₂O₅
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 262.2182

Cinoxacin

CAS: 28657-80-9

• Purity: 98%
• Molecular weight: 262.22g/mol

Cinoxacin

CAS: 28657-80-9

• Formula: C₁₂H₁₀N₂O₅
• Color and Shape: Neat
• Molecular weight: 262.22

PharmaVetResiMix 3 Quinolones-v18 10 µg/mL in Methanol

CAS: 115550-35-1 119478-55-6 14698-29-4 149676-40-4 19562-30-2 28657-80-9389-08-2 42835-25-6 51940-44-4 70458-96-7 74011-58-8 79660-72-3 82419-36-1 85721-33-1 91296-86-5 91296-87-6 93106-60-6 98079-52-8

• Color and Shape: Mixture

Smart Solutions™ v59 PharmaVetResiMix Kit 1

CAS: 100-90-3 113507-06-5 115550-35-1 117704-25-3 119478-55-6 122-11-2 1220-83-3 123997-26-2 127-71-9 127-79-7 144-82-1 144-83-2 14698-29-4 148-79-8 149676-40-4 155569-91-8 19562-30-2 20559-55-1 2447-57-6 28657-80-931430-15-6 31431-39-7 389-08-2 42835-25-6 43210-67-9 515-64-0 51940-44-4 53716-50-0 54029-12-8 54965-21-8 57-67-0 57-68-1 58306-30-2 59-40-5 63-74-1 651-06-9 68-35-9 68786-66-3 70288-86-7 70458-96-7 71751-41-2 72-14-0 723-46-6 729-99-7 74011-58-8 75184-71-3 79660-72-3 80-08-0 80-32-0 80-35-3 80983-34-2 82419-36-1 85721-33-1 88254-99-3 91296-86-5 91296-87-6 93106-60-6 948-71-0 98079-52-8

• Color and Shape: Mixture

GB/T 21312-2007 14 Quinolones 20 µg/mL in Methanol

CAS: 112398-08-0 14698-29-4 28657-80-9389-08-2 42835-25-6 51940-44-4 70458-92-3 70458-96-7 74011-58-8 82419-36-1 85721-33-1 91296-87-6 93106-60-6 98079-52-8

• Color and Shape: Mixture

Cinoxacin

CAS: 28657-80-9

• Formula: C₁₂H₁₀N₂O₅
• Color and Shape: Neat
• Molecular weight: 262.22

Cinoxacin

CAS: 28657-80-9

• Formula: C₁₂H₁₀N₂O₅
• Purity: ≥ 98.0%
• Color and Shape: White to off-white or pale yellow powder
• Molecular weight: 262.2

Cinoxacin

CAS: 28657-80-9

Please enquire for more information about Cinoxacin including the price, delivery time and more detailed …

• Formula: C₁₂H₁₀N₂O₅
• Purity: Min. 98 Area-%
• Color and Shape: Powder
• Molecular weight: 262.22 g/mol

Cinoxacin

CAS: 28657-80-9

Applications Cinoxacin is an antibacterial quinolone previously known for its use in the treatment of …

• Formula: C₁₂H₁₀N₂O₅
• Color and Shape: White To Off-White
• Molecular weight: 262.22