CAS 28957-04-2: Oridonin
Description:Oridonin is a natural compound classified as a diterpenoid, primarily derived from the plant Rabdosia rubescens, which is known for its traditional medicinal uses in Chinese herbal medicine. This compound exhibits a range of biological activities, including anti-inflammatory, anti-tumor, and antimicrobial properties, making it a subject of interest in pharmacological research. Oridonin's structure features a fused ring system typical of many diterpenoids, contributing to its biological activity. It is soluble in organic solvents but has limited solubility in water, which can influence its bioavailability and therapeutic applications. The compound has been studied for its potential effects on various cancer cell lines, showing promise in inducing apoptosis and inhibiting cell proliferation. Additionally, oridonin's mechanism of action may involve the modulation of signaling pathways related to cell survival and death. Overall, oridonin represents a significant area of interest for further research in drug development and natural product chemistry.
Formula:C20H28O6
InChI:InChI=1S/C20H28O6/c1-9-10-4-5-11-18-8-26-20(25,19(11,14(9)22)15(10)23)16(24)13(18)17(2,3)7-6-12(18)21/h10-13,15-16,21,23-25H,1,4-8H2,2-3H3/t10-,11-,12-,13?,15+,16?,18+,19-,20+/m0/s1
InChI key:InChIKey=SDHTXBWLVGWJFT-VSKLWXMZSA-N
SMILES:O=C1C(=C)C2CCC3C1(C2O)C4(O)OCC53C(O)CCC(C)(C)C5C4O
- Synonyms:
- (1alpha,5beta,6beta,7beta,8alpha,9beta,10alpha,13alpha,14R)-1,6,7,14-tetrahydroxy-7,20-epoxykaur-16-en-15-one
- (1alpha,5beta,6beta,7beta,9xi,10xi,14S)-1,6,7,14-tetrahydroxy-7,20-epoxykaur-16-en-15-one
- (1alpha,5beta,6beta,9beta,14S)-1,6,7,14-tetrahydroxy-7,20-epoxykaur-16-en-15-one
- (1α,6β,7α,14R)-7,20-Epoxy-1,6,7,14-tetrahydroxykaur-16-en-15-one
- (6Beta,7Beta)-1,6,7,14-Tetrahydroxy-7,20-Epoxykaur-16-En-15-One
- 6,11b-(Epoxymethano)-6a,9-methano-1H-cyclohepta[a]naphthalene, kaur-16-en-15-one deriv.
- Isodonal
- Isodonol
- Kaur-16-en-15-one, 7,20-epoxy-1,6,7,14-tetrahydroxy-, (1α,6β,7α,14R)-
- Kaur-16-en-15-one, 7α,20-epoxy-1α,6β,7,14-tetrahydroxy-, (14R)-
- See more synonyms
- NSC 250682
- Oridonine
- rubescensin A
- Oridonin