CAS 292135-78-5

Benzamide,3-(cyclopropylmethoxy)-N-(3,5-dichloro-1-oxido-4-pyridinyl)-4-(difluoromethoxy)-

Description:

Benzamide, 3-(cyclopropylmethoxy)-N-(3,5-dichloro-1-oxido-4-pyridinyl)-4-(difluoromethoxy)- is a chemical compound characterized by its complex structure, which includes a benzamide core substituted with various functional groups. The presence of a cyclopropylmethoxy group suggests potential steric effects and unique reactivity due to the cyclic structure. The dichloro and difluoromethoxy substituents indicate the compound may exhibit significant electronic properties, potentially influencing its biological activity and solubility. The pyridine ring contributes to the compound's aromatic character and may enhance its interaction with biological targets. This compound is likely to be of interest in medicinal chemistry, particularly for its potential pharmacological applications. Its specific properties, such as melting point, solubility, and reactivity, would depend on the overall molecular interactions and the presence of the various substituents. As with many compounds of this nature, further studies would be necessary to fully elucidate its characteristics and potential uses in various fields, including pharmaceuticals and agrochemicals.

Formula: C₁₇H₁₄Cl₂F₂N₂O₄

Synonyms:

• RofluMilast N-Oxide

Roflumilast N-Oxide

CAS: 292135-78-5

Formula: C₁₇H₁₄Cl₂F₂N₂O₄

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 419.21

Ref: 3B-R0217

Roflumilast N-Oxide

CAS: 292135-78-5

Color and Shape: Neat

Ref: 61-FOR3618.05

Benzamide, 3-(cyclopropylmethoxy)-N-(3,5-dichloro-1-oxido-4-pyridinyl)-4-(difluoromethoxy)-

CAS: 292135-78-5

Formula: C₁₇H₁₄Cl₂F₂N₂O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 419.2069

Ref: IN-DA002XQ1

Roflumilast N-Oxide

CAS: 292135-78-5

Formula: C₁₇H₁₄Cl₂F₂N₂O₄

Color and Shape: White To Off-White Solid

Molecular weight: 419.21

Ref: 4Z-R-373

3,5-Dichloro-4-(3-(Cyclopropylmethoxy)-4-(Difluoromethoxy)Benzamido)Pyridine 1-Oxide

CAS: 292135-78-5

3,5-Dichloro-4-(3-(Cyclopropylmethoxy)-4-(Difluoromethoxy)Benzamido)Pyridine 1-Oxide

Purity: 98%

Molecular weight: 419.21g/mol

Ref: 54-PC108437

Roflumilast N-oxide

CAS: 292135-78-5

Roflumilast N-oxide

Purity: ≥98%

Molecular weight: 419.21g/mol

Ref: 54-BUP09460

Roflumilast N-oxide

CAS: 292135-78-5

Molecular weight: 419.21

Ref: 10-F987692

Roflumilast N-Oxide

CAS: 292135-78-5

Formula: C₁₇H₁₄Cl₂F₂N₂O₄

Color and Shape: Neat

Molecular weight: 419.21

Ref: 86-MM3618.05

Roflumilast N-oxide

CAS: 292135-78-5

Roflumilast N-oxide is an inhibitor of PDE type 4.

Formula: C₁₇H₁₄Cl₂F₂N₂O₄

Purity: 98.19% - 99.69%

Color and Shape: Solid

Molecular weight: 419.21

Ref: TM-T4462

Roflumilast N-Oxide

Controlled Product

CAS: 292135-78-5

Applications Roflumilast-N-oxide is the active metabolite of Roflumilast (R639700).
References Chiba, M., et al.: Drug Metab. Dispos., 25, 1022 (1997), Jarvis, B., et al.: Drugs, 59, 891 (2000),

Formula: C₁₇H₁₄Cl₂F₂N₂O₄

Color and Shape: Neat

Molecular weight: 419.21

Ref: TR-R639710

Roflumilast N-oxide

CAS: 292135-78-5

Roflumilast N-oxide is a drug that is used to treat chronic obstructive pulmonary disease (COPD). It belongs to the group of drugs called phosphodiesterase-4 (PDE4) inhibitors. Roflumilast N-oxide inhibits the production of chemokines and reduces the recruitment of inflammatory cells, which improves lung function. Roflumilast N-oxide has been shown to reduce matrix metalloproteinases in vitro and in an experimental model in mice. In addition, roflumilast N-oxide has been shown to inhibit the transport of erythromycin into bronchial epithelial cells. The LC-MS/MS method is used for the determination of pharmacokinetic parameters for roflumilast N-oxide.

Formula: C₁₇H₁₄Cl₂F₂N₂O₄

Purity: Min. 95%

Molecular weight: 419.21 g/mol

Ref: 3D-FR27750

Roflumilast N-Oxide

CAS: 292135-78-5

Formula: C₁₇H₁₄Cl₂F₂N₂O₄

Molecular weight: 419.21

Ref: ST-EA-CP-R29001