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CAS 298-46-4

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Carbamazepine

Description:
Carbamazepine is an anticonvulsant and mood-stabilizing drug primarily used in the treatment of epilepsy, bipolar disorder, and neuropathic pain. It is classified as a tricyclic compound and is known for its ability to inhibit voltage-gated sodium channels, thereby stabilizing neuronal membranes and reducing the frequency of seizures. The chemical formula of carbamazepine is C15H12N2O, and it has a molecular weight of approximately 236.26 g/mol. This substance typically appears as a white to off-white crystalline powder and is poorly soluble in water but soluble in organic solvents like ethanol and acetone. Carbamazepine is metabolized in the liver, primarily through cytochrome P450 enzymes, and exhibits a relatively long half-life, necessitating careful monitoring of blood levels in patients. Side effects may include dizziness, drowsiness, and gastrointestinal disturbances, and it can interact with various medications, making it essential for healthcare providers to consider potential drug interactions when prescribing it.
Formula:C15H12N2O
InChI:InChI=1S/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H,(H2,16,18)
InChI key:InChIKey=FFGPTBGBLSHEPO-UHFFFAOYSA-N
SMILES:C(N)(=O)N1C=2C(=CC=CC2)C=CC=3C1=CC=CC3
Synonyms:
  • 5-Carbamoyl-5H-Dibenz[B,F]Azepine
  • 5H-Dibenz[B,F]Azepine-5-Carboxamide
  • 5H-dibenzo[b,f]azepine-5-carboxamide
  • Amizepin
  • Biston
  • CBZ
  • Calepsin
  • Carbamazepen
  • Carbamazepin
  • Carbamazepina
  • See more synonyms
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