CAS 30516-87-1: Azidothymidine

Description: Azidothymidine, commonly known as AZT or zidovudine, is an antiretroviral medication primarily used in the treatment of HIV/AIDS. It is a nucleoside reverse transcriptase inhibitor (NRTI) that works by inhibiting the reverse transcriptase enzyme, thereby preventing the replication of the virus. AZT is characterized by its azido group, which distinguishes it from thymidine, a naturally occurring nucleoside. The compound is typically administered in its phosphate form, which is activated within the body to exert its antiviral effects. AZT is known for its ability to reduce the viral load in patients and improve immune function, although it may also cause side effects such as bone marrow suppression and gastrointestinal issues. Its chemical structure includes a pyrimidine base, and it is soluble in water, making it suitable for various formulations. AZT has played a significant role in HIV treatment regimens and remains a critical component in the management of the disease, particularly in combination therapies.

Formula: C₁₀H₁₃N₅O₄

InChI: InChI=1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1

InChI key: InChIKey=HBOMLICNUCNMMY-XLPZGREQSA-N

SMILES: [N-]=[N+]=NC1CC(OC1CO)N2C=C(C(=O)NC2=O)C

Synonyms:

• 1-(3-Azido-2,3-Dideoxy-Beta-D-Ribofuranosyl)Thymine
• 1-(3-azido-2,3-dideoxy-beta-D-threo-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
• 1-(3-azido-2,3-dideoxypentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
• 1-(4-Azido-5-Hydroxymethyl-Tetrahydro-Furan-2-Yl)-5-Methyl-1H-Pyrimidine-2,4-Dione
• 1-[(3xi)-3-azido-2,3-dideoxy-beta-D-glycero-pentofuranosyl]-5-methylpyrimidine-2,4(1H,3H)-dione
• 3'-Azido-3'-Deoxythymidine
• 3'-Azido-3'-desoxythymidine
• 3'-Azido-3'-thymidine
• 3'-Azidothymidine
• 3'-Deoxy-3'-azidothymidine
• 3-Azido-3-deoxy-thymidine
• 3′-Azt
• AZT
• AZT (pharmaceutical)
• Azidothymidine
• Azitidin
• Bw-A 509U
• Compound S
• Nsc 602670
• Retrovir
• Retrovir IV
• Retrovis
• Thymidine, 3'-azido-3'-deoxy-
• Timazid
• Viro-Z
• ZDV
• ZVD
• Zido-H
• Zidovudine(AZT)

3'-Azido-3'-deoxythymidine

CAS: 30516-87-1

• Formula: C₁₀H₁₃N₅O₄
• Purity: >98.0%(T)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 267.25

3'-Azido-3'-deoxythymidine, 98%

CAS: 30516-87-1

3'-Azido-3'-deoxythymidine is a Anti-viral agent, and also used as a reverse transcriptase inhibitor active against …

• Formula: C₁₀H₁₃N₅O₄
• Purity: 98%
• Color and Shape: White to yellow, Powder
• Molecular weight: 267.25

Zidovudine impurity standard

CAS: 25526-94-7 30516-87-150-89-5 65-71-4

• Color and Shape: Off White Solid

Zidovudine RS

CAS: 30516-87-1

• Formula: C₁₀H₁₃N₅O₄
• Molecular weight: 267.2413

Zidovudine for system suitability A CRS

CAS: 30516-87-1

Zidovudine CRS

CAS: 30516-87-1

• Formula: C₁₀H₁₃N₅O₄
• Color and Shape: White. Light Brown. Powder.
• Molecular weight: 267.2413

Zidovudine

CAS: 30516-87-1

• Formula: C₁₀H₁₃N₅O₄
• Purity: 99.3%
• Color and Shape: Off-White
• Molecular weight: 267.09675

Zidovudine

CAS: 30516-87-1

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

• Formula: C₁₀H₁₃N₅O₄
• Color and Shape: White Light Yellow Crystalline Solid
• Molecular weight: 267.24 g/mol

Thymidine, 3'-azido-3'-deoxy-

CAS: 30516-87-1

• Formula: C₁₀H₁₃N₅O₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 267.24132000000003

Zidovudine

CAS: 30516-87-1

Zidovudine, a synthetic dideoxynucleoside, blocks DNA replication by inhibiting DNA polymerase after activation.

• Formula: C₁₀H₁₃N₅O₄
• Purity: 99.84% - 99.91%
• Color and Shape: White To Off-White Crystals
• Molecular weight: 267.24

Zidovudine

CAS: 30516-87-1

• Purity: 99.9%
• Molecular weight: 267.24g/mol

Zidovudine-13C-d3

CAS: 30516-87-1

• Formula: C₉₁₃CH₁₀D₃N₅O₄
• Color and Shape: Off-White Solid
• Molecular weight: 271.26

Zidovudine

CAS: 30516-87-1

• Formula: C₁₀H₁₃N₅O₄
• Color and Shape: White To Off-White Solid
• Molecular weight: 267.25

Zidovudine

CAS: 30516-87-1

• Formula: C₁₀H₁₃N₅O₄
• Color and Shape: Neat
• Molecular weight: 267.24

3'-Azido-3'-deoxythymidine, 98%

CAS: 30516-87-1

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₀H₁₃N₅O₄
• Purity: 98%
• Color and Shape: Powder, White to light yellow
• Molecular weight: 267.25

Zidovudine

CAS: 30516-87-1

• Formula: C₁₀H₁₃N₅O₄
• Color and Shape: Neat
• Molecular weight: 267.24

3'-Azido-3'-deoxythymidine

CAS: 30516-87-1

• Molecular weight: 267.24g/mol

3'-Azido-3'-deoxythymidine

CAS: 30516-87-1

• Formula: C₁₀H₁₃N₅O₄
• Purity: 97%
• Color and Shape: off-white solid
• Molecular weight: 267.24g/mol

3''-Azido-3''-deoxythymidine

CAS: 30516-87-1

• Formula: C₁₀H₁₃N₅O₄
• Purity: ≥ 98.0%
• Color and Shape: White to off-white crystalline powder
• Molecular weight: 267.24

Zidovudine RS

CAS: 30516-87-1

• Color and Shape: White To Pale Yellow-White Solid Powder