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CAS 309915-13-7

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1H-Indole-3-acetamide,6-chloro-5-[[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]carbonyl]-N,N,1-trimethyl-a-oxo-, rel-

Description:
1H-Indole-3-acetamide, 6-chloro-5-[[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]carbonyl]-N,N,1-trimethyl-a-oxo-, rel- (CAS 309915-13-7) is a complex organic compound characterized by its indole core structure, which is a bicyclic compound consisting of a benzene ring fused to a pyrrole ring. This substance features a chloro substituent at the 6-position and a piperazine moiety that contributes to its pharmacological properties. The presence of a fluorophenyl group enhances its lipophilicity, potentially influencing its biological activity. The compound also contains an acetamide functional group, which may play a role in its interaction with biological targets. Its stereochemistry, indicated by the (2R,5S) configuration, suggests specific spatial arrangements that can affect its binding affinity and efficacy. Overall, this compound is of interest in medicinal chemistry, particularly for its potential therapeutic applications, although detailed studies would be necessary to elucidate its specific biological effects and mechanisms of action.
Formula:C27H30ClFN4O3
InChI:InChI=1S/C27H30ClFN4O3/c1-16-13-33(17(2)12-32(16)14-18-6-8-19(29)9-7-18)26(35)21-10-20-22(25(34)27(36)30(3)4)15-31(5)24(20)11-23(21)28/h6-11,15-17H,12-14H2,1-5H3/t16-,17+/m0/s1
InChI key:ZMELOYOKMZBMRB-DLBZAZTESA-N
SMILES:C[C@@H]1CN([C@H](CN1C(=O)C2=C(C=C3C(=C2)C(=CN3C)C(=O)C(=O)N(C)C)Cl)C)CC4=CC=C(C=C4)F
Synonyms:
  • Sd-282
Found 1 products.
  • rac-Talmapimod
    TRC
    + Info

    rac-Talmapimod

    Controlled Product
    CAS:

    Applications rac-Talmapimod is a p38α-selective mitogen-activated protein kinase inhibitor, SD-282, to clinIcally used serum-free culture medium. By reducing interleukin 6 mRNA expression as well as IL-6, -8, granulocyte-macrophage colony-stimulating factor release and preventing β-cell apoptosis improved cultured human pancreatic islet cell recovery in serum-free medium. An α-isoform selective inhibitor for p38 MAP kinase
    References Omori, K., et al.: Pancreas (Hagerstown, MD, United States), 39, 436 (2010); Koppelman, B., et al.: Pharmacology, 81, 204 (2008)

    Formula:C27H30ClFN4O3
    Color and Shape:Neat
    Molecular weight:513.0

    Ref: TR-T005540

    500mg
    9,870.00€