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CAS 31431-39-7

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Mebendazole

Description:
Mebendazole is a broad-spectrum anthelmintic agent primarily used to treat parasitic worm infections, such as those caused by roundworms, hookworms, and whipworms. It belongs to the benzimidazole class of compounds and functions by inhibiting the polymerization of tubulin, which disrupts the formation of microtubules in the parasite, ultimately leading to its death. Mebendazole is typically administered orally and is poorly absorbed in the gastrointestinal tract, which allows it to exert its effects primarily within the intestines. The compound is characterized by its white to off-white crystalline powder form, with a relatively low solubility in water but higher solubility in organic solvents. Its chemical formula is C16H19N3O3, and it has a molecular weight of approximately 295.34 g/mol. Mebendazole is generally well-tolerated, with side effects being rare and usually mild, such as gastrointestinal disturbances. It is important to note that while effective against many helminths, it is not effective against all types of parasitic infections, and its use should be guided by appropriate medical advice.
Formula:C16H13N3O3
InChI:InChI=1S/C16H13N3O3/c1-22-16(21)19-15-17-12-8-7-11(9-13(12)18-15)14(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,17,18,19,21)
InChI key:InChIKey=OPXLLQIJSORQAM-UHFFFAOYSA-N
SMILES:C(=O)(C=1C=C2C(N=C(NC(OC)=O)N2)=CC1)C3=CC=CC=C3
Synonyms:
  • (5-Benzoyl-1H-benzimidazol-2-yl)carbamic acid methyl ester
  • 2-Benzimidazolecarbamic acid, 5-benzoyl-, methyl ester
  • 5-Benzoyl-2-benzimidazolecarbamic acid methyl ester
  • Bantenol
  • Besantin
  • Carbamic acid, N-(6-benzoyl-1H-benzimidazol-2-yl)-, methyl ester
  • Equivurm Plus
  • Lomper
  • Mebendazol
  • Mebendazole
  • See more synonyms
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