CAS 32449-98-2

(3beta,22alpha,25R)-spirosol-5-en-3-yl 4-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside

Description:

The chemical substance known as "(3beta,22alpha,25R)-spirosol-5-en-3-yl 4-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside," with the CAS number 32449-98-2, is a glycoside that features a spirosolane skeleton, which is a type of steroid-like structure. This compound is characterized by the presence of a spiro carbon framework, which contributes to its unique three-dimensional conformation. The molecule contains a sugar moiety, specifically a 6-deoxy-alpha-L-mannopyranosyl group linked to a beta-D-glucopyranoside, indicating that it has both glycosidic and stereochemical complexity. The presence of multiple hydroxyl groups in the sugar components enhances its solubility in polar solvents and may contribute to its biological activity. Such compounds often exhibit various pharmacological properties, including potential anti-inflammatory or antimicrobial effects, making them of interest in medicinal chemistry. The specific stereochemistry at the 3, 22, and 25 positions is crucial for its biological interactions and overall stability.

Formula: C₃₉H₆₃NO₁₁

InChI: InChI=1/C39H63NO11/c1-18-8-13-39(40-16-18)19(2)28-26(51-39)15-25-23-7-6-21-14-22(9-11-37(21,4)24(23)10-12-38(25,28)5)48-36-33(46)31(44)34(27(17-41)49-36)50-35-32(45)30(43)29(42)20(3)47-35/h6,18-20,22-36,40-46H,7-17H2,1-5H3/t18-,19+,20+,22+,23-,24+,25+,26+,27-,28+,29+,30-,31-,32-,33-,34-,35+,36-,37+,38+,39-/m1/s1

InChI key: KRQDMAXNTWLTDZ-HCTICQNOSA-N

SMILES: C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC=C6[C@@]5(CC[C@@H](C6)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O[C@H]8[C@@H]([C@@H]([C@H]([C@@H](O8)C)O)O)O)O)O)C)C)C)NC1

Synonyms:

• beta-D-glucopyranoside, (3beta,22alpha,25R)-spirosol-5-en-3-yl 4-O-(6-deoxy-alpha-L-mannopyranosyl)-
• (3beta,22alpha,25R)-Spirosol-5-en-3-yl 4-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside
• β-D-Glucopyranoside, (3β,22α,25R)-spirosol-5-en-3-yl 4-O-(6-deoxy-α-L-mannopyranosyl)-
• beta2-Solamargine
• Khasianine 32449-98-2
• o-α-L-rhaMnopyranosyl-(1 → 4 glu)-O-(3)-β-D-glucopyranosyl solasadine
• khasianine
• β2-Solamargine
• b-D-Glucopyranoside, (3b,22a,25R)-spirosol-5-en-3-yl 4-O-(6-deoxy-a-L-mannopyranosyl)-
• KHASIANINE;Β2-SOLAMARGINE

Khasianine

CAS: 32449-98-2

Khasianine

Formula: C₃₉H₆₃NO₁₁

Purity: ≥98%

Molecular weight: 721.92

Ref: 54-BUP09314

Khasianine

CAS: 32449-98-2

Formula: C₃₉H₆₃NO₁₁

Molecular weight: 721.93

Ref: 7W-GY3604

Khasianine

CAS: 32449-98-2

Formula: C₃₉H₆₃NO₁₁

Purity: 98%

Color and Shape: Solid

Molecular weight: 721.9176

Ref: IN-DA00CIID

Khasianine (Standard)

CAS: 32449-98-2

Khasianine (Standard) is a reference standard for research and analysis in studies involving Khasianine. Khasianine has strong activity against liver damage induced by CCl4.

Formula: C₃₉H₆₃NO₁₁

Color and Shape: Solid

Molecular weight: 721.9176

Ref: TM-TMSM-2258

Khasianine

CAS: 32449-98-2

Khasianine exhibits strong activity against liver damage induced by CCl4.

Formula: C₃₉H₆₃NO₁₁

Purity: 95%~99%

Molecular weight: 721.929

Ref: BP-BP0830

Khasianine

CAS: 32449-98-2

Khasianine has strong activity against liver damage induced by CCl4.

Formula: C₃₉H₆₃NO₁₁

Purity: 98% - 99.93%

Color and Shape: Solid

Molecular weight: 721.9176

Ref: TM-T4035

Khasianine

CAS: 32449-98-2

Natural alkaloid

Formula: C₃₉H₆₃NO₁₁

Purity: ≥ 95.0 % (HPLC)

Molecular weight: 721.92

Ref: 5G-84230

Khasianine

CAS: 32449-98-2

Formula: C₃₉H₆₃NO₁₁

Molecular weight: 721.9

Ref: BE-RMT21404

Khasianine

Controlled Product

CAS: 32449-98-2

Stability Hygroscopic
Applications Khasianine is a steroidal glycoalkaloid which is obtained from black nightshade (Solanum Nigrum L.) which displays antitumor activity.
References Ding, X. et al.: Food. Chem., 141, 1181 (2013);

Formula: C₂₄H₂₆O₅S

Color and Shape: Neat

Molecular weight: 426.525

Ref: TR-K520000

Khasianine

CAS: 32449-98-2

Khasianine is a diterpenoid alkaloid that has potent inhibitory activity against the growth of cancer cells. Khasianine has been shown to induce apoptosis in MCF-7 cells. It inhibits the synthesis of DNA, RNA, and protein by binding to the hydroxyl group on the 3' position of DNA, which prevents transcription and replication. Khasianine also has significant cytotoxicity in a hydroxyl matrix effect study. This drug is extracted from plants using an extractant such as ethyl acetate or dichloromethane. The chemical structure of khasonine is similar to that of steroidal alkaloids, with a glycosidic bond between two molecules. The molecular weight is 313 Da and it can be identified by its nmr spectra

Formula: C₃₉H₆₃NO₁₁

Purity: Min. 95%

Molecular weight: 721.92 g/mol

Ref: 3D-HBA44998