CAS 3546-41-6

Pyrvinium pamoate

Description:

Pyrvinium pamoate is a synthetic compound primarily used as an anthelmintic agent, effective against certain intestinal parasites. It is characterized by its bright red color and is often found in the form of a salt, specifically as a pamoate (or embonate) salt, which enhances its solubility and bioavailability. The compound functions by inhibiting the energy metabolism of parasites, leading to their eventual death. Pyrvinium pamoate is typically administered orally and is known for its relatively low toxicity in humans when used at therapeutic doses. Its mechanism of action involves interference with the parasite's ability to utilize glucose, which is crucial for their survival. Additionally, it has been studied for potential applications beyond parasitic infections, including its effects on certain types of cancer cells. However, its use is primarily focused on treating infections caused by helminths. As with any medication, it is important to consider potential side effects and contraindications when prescribing or using pyrvinium pamoate.

Formula: C₂₆H₂₈N₃C₂₃H₁₄O₆

InChI: InChI=1S/C26H28N3.C23H16O6/c1-19-17-21(20(2)29(19)24-9-7-6-8-10-24)11-13-23-14-12-22-18-25(27(3)4)15-16-26(22)28(23)5;24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29/h6-18H,1-5H3;1-10,24-25H,11H2,(H,26,27)(H,28,29)/q+1;/p-2

InChI key: InChIKey=ZFWFZMYQXOKWIY-UHFFFAOYSA-L

SMILES: C(C=1C2=C(C=C(C([O-])=O)C1O)C=CC=C2)C=3C4=C(C=C(C([O-])=O)C3O)C=CC=C4.CC=1N(C(C)=CC1C=CC2=[N+](C)C3=C(C=C2)C=C(N(C)C)C=C3)C4=CC=CC=C4

Synonyms:

• 2-Naphthalenecarboxylic acid, 4,4′-methylenebis[3-hydroxy-, ion(2-), bis[6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methylquinolinium]
• 2-Naphthoic acid, 4,4′-methylenebis[3-hydroxy-, ion(2-), bis[6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenylpyrrol-3-yl)vinyl]-1-methylquinolinium]
• 6-(dimethylamino)-2-[(E)-2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methylquinolinium 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylate
• 6-Dimethylamino-2-[2-(2,5-dimethyl-1-phenyl-3-pyrryl)vinyl]-1-methylquinolinium salt of 2,2′-dihydroxy-1,1′-dinaphthylmethane-3,3′-dicarboxylic acid
• Alnoxin
• Altolat
• Bis(6-Dimethylamino-2-(2-(2,5-Dimethyl-1-Phenylpyrrol-3-Yl)Vinyl)-1-Methylquinolinium) 3,3-Dihydroxy-4,4-Methylenedi-2-Naphthoate
• Bis[6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenylpyrrol-3-yl)vinyl]-1-methylquinolinium] 4,4′-methylenebis[3-hydroxy-2-naphthoate]
• Molevac
• NSC 223622
• Neo-Oxypaat
• Pamovin
• Poquil
• Povan
• Povanil
• Povanyl
• Pyrcon
• Pyrvinium Embonate
• Quinolinium, 6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methyl-, 4,4′-methylenebis[3-hydroxy-2-naphthalenecarboxylate] (2:1)
• Quinolinium, 6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methyl-, salt with 4,4′-methylenebis[3-hydroxy-2-naphthalenecarboxylic acid] (2:1)
• Quinolinium, 6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenylpyrrol-3-yl)vinyl]-1-methyl-, salt with 4,4′-methylenebis[3-hydroxy-2-naphthoic acid] (2:1)
• Tolapin
• Vanquin
• Vermitibier
• Viprynium Embonate

Pyrvinium pamoate salt hydrate

CAS: 3546-41-6

Formula: C₂₆H₂₈N₃·5C₂₃H₁₄O₆·xH₂O

Purity: ≥ 98.0%

Color and Shape: Red powder

Molecular weight: 575.70 (anhydrous)

Ref: 7W-GL7591

2-(2-(2,5-Dimethyl-1-Phenyl-1H-Pyrrol-3-Yl)Vinyl)-6-(Dimethylamino)-1-Methylquinolin-1-Ium Bis-4,4'-Methylenebis(3-Hydroxy-2-Naphthoate)

CAS: 3546-41-6

2-(2-(2,5-Dimethyl-1-Phenyl-1H-Pyrrol-3-Yl)Vinyl)-6-(Dimethylamino)-1-Methylquinolin-1-Ium Bis-4,4'-Methylenebis(3-Hydroxy-2-Naphthoate)

Purity: 99%

Molecular weight: 1151.39g/mol

Ref: 54-OR1025533

Pyrvinium pamoate

CAS: 3546-41-6

Pyrvinium pamoate

Purity: ≥98%

Molecular weight: 575.71g/mol

Ref: 54-BUP06324

Pyrvinium Pamaote

CAS: 3546-41-6

Formula: C₂₆H₂₈N₃·C₂₃H₁₄O₆

Color and Shape: Red Solid

Molecular weight: 2*382.53 386.36

Ref: 4Z-P-269004

Pyrvinium pamoate

CAS: 3546-41-6

Pyrvinium pamoate (Pyrvinium embonate) is an old anthelminthic medicine for the treatment of enterobiasis , which re-attracts attention as an anti-cancer drug

Formula: C₂₆H₂₈N₃C₂₃H₁₄O₆

Purity: 99.76% - >99.99%

Color and Shape: Solid

Molecular weight: 575.71

Ref: TM-T7333

Pyrvinium Pamoate

Controlled Product

CAS: 3546-41-6

Formula: C₂₆H₂₈N₃·C₂₃H₁₄O₆

Color and Shape: Neat

Molecular weight: 1151.39

Ref: TR-P999010

Pyrvinium Pamoate (DISCONTINUED)

CAS: 3546-41-6

Drugs containing a quinoline or isoquinoline ring-system (whether or not hydrogenated) not further fused

Formula: C₂₆H₂₈N₃C₂₃H₁₄O₆

Color and Shape: Dark Red Powder

Molecular weight: 1151.4

Ref: 45-1592001