CAS 372-48-5

2-Fluoropyridine

Description:

2-Fluoropyridine is a heterocyclic aromatic compound characterized by a pyridine ring with a fluorine atom substituted at the second position. Its molecular formula is C5H4FN, and it has a molecular weight of approximately 99.09 g/mol. This compound is a colorless to pale yellow liquid with a distinctive odor. It is polar and exhibits moderate solubility in water, while being more soluble in organic solvents such as ethanol and ether. 2-Fluoropyridine is known for its role as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, owing to the reactivity of the fluorine atom, which can participate in nucleophilic substitution reactions. Additionally, it can undergo electrophilic aromatic substitution, making it a valuable building block in organic synthesis. Safety considerations include its potential to cause irritation to the skin, eyes, and respiratory system, necessitating appropriate handling and storage measures. Overall, 2-fluoropyridine is an important compound in the field of organic chemistry and medicinal chemistry.

Formula: C₅H₄FN

InChI: InChI=1/C5H4FN/c6-5-3-1-2-4-7-5/h1-4H

InChI key: InChIKey=MTAODLNXWYIKSO-UHFFFAOYSA-N

SMILES: FC1=CC=CC=N1

Synonyms:

• 2-Fluoropyride
• 2-Pyridyl fluoride
• NSC 5077
• Pyridine, 2-fluoro-
• 2-Fluoropyridine
• 2-fluoroppyridine
• 2-CYANOPHENYLBORONIC ACID
• 2-Fluoropyridine,99%
• 2-fluoro-pyridin
• 2-Fluoroypyridine

2-Fluoropyridine

CAS: 372-48-5

Formula: C₅H₄FN

Purity: >98.0%(GC)

Color and Shape: Colorless to Light orange to Yellow clear liquid

Molecular weight: 97.09

Ref: 3B-F0217

2-Fluoropyridine, 99%

CAS: 372-48-5

2-Fluoropyridine is a useful precursor of 2,3-disubstituted pyridines which is made by the possibility of metallation at C-3, together with the ready nucleophilic displacement of the activated fluorine. It can also react with thiophene to get 2-thiophen-2-yl-pyridine. It is used in the synthesis of

Formula: C₅H₄FN

Purity: 99%

Color and Shape: Clear colorless to pale yellow, Liquid

Molecular weight: 97.09

Ref: 02-A11627

2-Fluoropyridine

CAS: 372-48-5

2-Fluoropyridine

Formula: C₅H₄FN

Purity: 99%

Color and Shape: Yellow Liquid

Molecular weight: 97.09036

Ref: 54-PC4200

2-Fluoropyridine

CAS: 372-48-5

Formula: C₅H₄FN

Purity: 98%

Color and Shape: Liquid

Molecular weight: 97.0904

Ref: IN-DA0033BU

2-Fluoropyridine

CAS: 372-48-5

2-Fluoropyridine

Formula: C₅H₄FN

Purity: 97%

Color and Shape: Liquid

Molecular weight: 97.09036

Ref: 54-PC57491

2-Fluoropyridine

CAS: 372-48-5

Formula: C₅H₄FN

Molecular weight: 97.09

Ref: 7W-GK3520

2-Fluoropyridine

CAS: 372-48-5

Formula: C₅H₄FN

Purity: 98.0%

Color and Shape: Liquid

Molecular weight: 97.092

Ref: 10-F001297

2-Fluoropyridine

CAS: 372-48-5

2-Fluoropyridine

Formula: C₅H₄FN

Purity: 98%

Molecular weight: 97.09

Ref: IN-DG33442

2-Fluoropyridine

CAS: 372-48-5

2-Fluoropyridine is an organic compound with the chemical formula CHF. It is a colorless liquid that has a strong odor and burns easily. The compound has been used in the synthesis of pharmaceutical drugs, pesticides, and dyestuff intermediates. 2-Fluoropyridine is synthesized by reacting anhydrous sodium or chlorine with amines or ammonia in the presence of hydrogen gas. The reaction mechanism for this reaction involves nucleophilic attack on the carbon atom adjacent to the fluorine atom followed by displacement of chlorine. Asymmetric synthesis can also be performed by using chiral auxiliaries to generate one enantiomer of 2-fluoropyridine from an equimolar mixture of reactants.

Formula: C₅H₄FN

Purity: Min. 95%

Color and Shape: Colorless Clear Liquid

Molecular weight: 97.09 g/mol

Ref: 3D-FF45043

2-Fluoropyridine

Controlled Product

CAS: 372-48-5

Applications 2-Fluoropyridine acts as a reagent in the synthesis of aminopyrimidines with antimicrobial and antifungal properties.
References Hedidi, M., et al.: Eur. J. Org. Chem., 39, 5903 (2017)

Formula: C₅H₄FN

Color and Shape: Neat

Molecular weight: 97.09

Ref: TR-F596295