CAS: 405169-16-6 - Dovitinib

Formula: C₂₁H₂₁FN₆O

InChI: InChI=1S/C21H21FN6O/c1-27-7-9-28(10-8-27)12-5-6-14-16(11-12)25-20(24-14)18-19(23)17-13(22)3-2-4-15(17)26-21(18)29/h2-6,11H,7-10H2,1H3,(H,24,25)(H3,23,26,29)

InChI key: InChIKey=PIQCTGMSNWUMAF-UHFFFAOYSA-N

SMILES: O=C1NC=2C=CC=C(F)C2C(N)=C1C3=NC4=CC=C(C=C4N3)N5CCN(C)CC5

Synonyms:

• 2(1H)-Quinolinone, 4-amino-5-fluoro-3-[5-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-
• 2(1H)-Quinolinone, 4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-
• 4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one
• 4-Amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone
• Gfki 258
• Tk-258
• Tki 258

2(1H)-Quinolinone,4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-

CAS: 405169-16-6

• Formula: C₂₁H₂₁FN₆O
• Color and Shape: Solid
• Molecular weight: 392.4294

Dovitinib

CAS: 405169-16-6

• Formula: C₂₁H₂₁FN₆O
• Molecular weight: 392.43

Dovitinib-d8

CAS: 405169-16-6

• Formula: C₂₁H₁₃D₈FN₆O
• Color and Shape: Yellow Solid
• Molecular weight: 400.49

Dovitinib

CAS: 405169-16-6

• Formula: C₂₁H₂₁FN₆O
• Molecular weight: 392.44

Dovitinib

CAS: 405169-16-6

Dovitinib (CHIR-258) (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit, IC50: …

• Formula: C₂₁H₂₁FN₆O
• Purity: 99.78%
• Color and Shape: Solid
• Molecular weight: 392.43

Dovitinib base

CAS: 405169-16-6

Receptor tyrosine kinase inhibitor; anti-angiogenesis; anti-oncogenesis

• Formula: C₂₁H₂₁FN₆O
• Purity: Min. 98 Area-%
• Color and Shape: Powder
• Molecular weight: 392.43 g/mol